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The CCTS Investigator
Advancing Today's Discoveries To Improve Health For All
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What's New in Translational Science? | |
NIH Gene Therapy Team Reveals Its Path to FDA Orphan Drug and Rare Pediatric Disease Designations | |
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When NCATS received an Orphan Drug Designation (ODD) from the U.S. Food and Drug Administration (FDA), it marked a key accomplishment for researchers in the NIH's Platform Vector Gene Therapy (PaVe-GT) project. NCATS received the ODD for PaVe-GT's AAV9-hPCCA (NCATS-BL0746) investigational gene therapy [external link] to treat a form of propionic acidemia, a rare metabolic disorder.
Read More [external link]
Image Courtesy of NCATS
Image description: Winding road with multi-colored capsules that have graphics of DNA. Light blue background with NCATS logo in bottom right corner.
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Call for Abstracts!
Appalachian Translational Research Network Annual Health Summit
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The 13th Annual Appalachian Translational Research Network (ATRN) Health Summit.
October 5-6, 2023
Hosted by West Virginia University, Morgantown, WV
General Guidelines for Abstract Submission
The ATRN is most interested in research, programs and community efforts that focus on priority health topics impacting Appalachian communities.
Abstracts may include basic laboratory research, clinical and translational research, community-based research, epidemiological and/or populations studies, dissemination and implementation practices, outcomes research, health services research, evidence-based programs, program evaluations or best practices in community organizations or clinical settings.
Call for Abstracts Due: July 17, 2023
More Information and Submit Abstract [Word Doc]
Image description: Dashed circle that transitions from light green to teal. Inside of the circle following the curve in blue reads "Appalachian Translational Research Network." Below that is a graphic of mountain and then below that is "ATRN" in blue text.
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Traumatic Brain Injury and Psychological Health Research Program | |
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The Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) has released five funding announcements [external link] for FY23. The TBIPHRP anticipates funding approximately 70 awards ranging from $500k total direct costs up to $5M total direct costs. Research topics included are:
- Traumatic brain injury (TBI) (including associated sequelae)
- Blast
- TBI biomarkers
- Treatments (including rehabilitation) that can be applied in the acute, post-acute and chronic phase
- Psychological health (post-traumatic stress disorder, adjustment disorders, acute stress reaction, depression)
- Psychological health trajectories associated with trauma
- Crosscutting prevention approaches to prevent adverse outcomes such as suicide, violence or substance use
- Suicide prevention
- Sexual harassment and sexual assault prevention, perpetration, victimization and response
- Mobile health/telemedicine
- Health services research (including comparative effectiveness and implementation science)
- Community-based participatory research
Access Currently Open Funding Announcements [external link]
Contact Help@eBRAP.org [email] or call 301-682-5507 with questions.
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CCTS Trainees Attend Translational Science Conference in Washington, DC | |
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CCTS TL1 postdoctoral trainees Laura Beth Kalvas and Kristen Fox were among several trainees who attended the Translational Science Conference in Washington, DC, April 18 - 20.
In addition to poster presentations and scientific talks, the conference included a Mock Study Section, Speed Mentoring, a trainee luncheon and the opportunity to talk to Congressional staff members about the value of biomedical research. Drs. Kalvas and Fox are pictured here on Capitol Hill.
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The National Institutes of Health Office of Intramural Training and Education is offering their "Becoming a Resilient Scientist Series" in a virtual format of four webinars beginning June 8. The program is designed to help graduate and professional students develop the confidence and resilience they need to navigate challenging situations in school, work and life.
The series includes four (summer) webinars, each followed by a small-group discussion. These sessions focus on strategies for academic success, thriving in research and healthcare careers, building resilience, overcoming obstacles and mentoring. Attending the entire series is recommended as concepts and themes will be developed progressively, allowing you to integrate and refine the information.
Previous participants reported increased resilience, improved stress management and highly recommended the series.
First session is June 8! Enroll today.
More Information and Register for Becoming a Resilient Scientist Series [external link]
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Steps to Request IT Resources for Research | |
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Researchers interested in using IT resources must submit all IT requests through the Research Shareholder Group (RSG). Requests must include the following before being reviewed by the RSG:
- The Ohio State University Wexner Medical Center Risk Assessment
- IRB approval status
- Funding status
- Security status
- Specific technology request
IT requests may be delayed if all of the above information is not included in the RSG request. RSG requests should be submitted here under the tab Requesting an IT Project. [external link]
*Please note that an Ohio State Wexner Medical Center Risk Assessment must be completed before submitting a request to add a software system for research. It is important to start the Risk Assessment process early as it will take additional time.
Click here for the Risk Assessment request link [external link]
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Attention researchers! Are you recruiting for a study and not sure where to start? Use StudySearch to list your study!
StudySearch is a resource for researchers to list their studies. StudySearch allows researchers to share information about their clinical trials for people to volunteer and help find new safe and effective treatments.
Visit StudySearch [external link] to list your IRB approved study today!
Questions? Contact Clara Kalis at Clara.Kalis@osumc.edu [email] for more information!
Image description: Study Search logo in gray with both "S"'s in scarlet.
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ResearchMatch is a complimentary tool for researchers to connect directly with individuals interested in participating in clinical trials.
Researchers, if you are interested in learning how you can use ResearchMatch, a complimentary recruitment method, to help you recruit participants for your study, please email the recruitment and retention manager, Mary Becker [email], and the recruitment and retention coordinator, Clara Kalis [email], at the CCTS for more information on how to get started.
If you are interested in having someone from the CCTS Recruitment and Retention program speak at your staff and/or departmental meetings about our services and how we can help you meet your clinical trial recruitment goals, please contact Mary Becker [email].
Explore ResearchMatch [external link]
Image description: Green megaphone with orange callout with text in the center saying "Calling All Researchers" in all capital black letters. Below is the ResearchMatch logo in green and orange.
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The CCTS Recruitment and Retention Program
They have numerous events coming up to communicate the importance about participating in clinical trials.
Recruitment and Retention is also seeing increased success in recruiting for clinical trials on Facebook.
Read More About the Upcoming Events and a Facebook Ad Testimonial from Rosie Bauder [external link]
Image Description: Recruitment and Retention Manager, Mary Becker, and Coordinator, Clara Kalis, at the 2022 Healthy Community Day
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The CCTS Funding Opportunities and Events | |
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Tuesday, June 6, 2023, 11 a.m.- noon
Part 1: Introduction to financial management tools for your grants and contracts
Do you know where to find the financials for your grants and contracts managed by the Office of Sponsored Programs? Do you know what all the numbers mean? Join us for this session introducing tools available to researchers to understand how much you can spend, what you’ve spent, what you’ve committed to spending and other useful information for managing your awards.
Tuesday, June 13, 2023, 11 a.m. - noon
Part 2: Using financial management tools to manage your grants and contracts
Once you know how to access and understand the information in the financial management tools and reports it’s time to use them to manage your grants and contracts. Learn how to think about your award’s financials in a proactive way, spot problems and research them and what kind of information is not available in the tools.
More Information and Register [external link]
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Ian C. Davis, PhD, and Anda Young, DVM, both of The Ohio State University College of Veterinary Medicine, used client-owned dogs admitted to the small animal ICU at the Ohio State Veterinary Medical Center as a "real-world" model to test the repurposing of an old drug, citicoline, as a treatment for hypoxemic acute respiratory failure. Citicoline was developed for neurologic conditions but Dr. Davis had found that it worked to treat respiratory failure in mice.
Come to learn about how they came to use this model and their results.
When: June 14, 2023, noon - 1 p.m.
Where: Online
More Information and Register [external link]
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This Recruitment Cafe will leverage the experiences of study teams as they attempt to navigate the recruitment and retention landscape and will include a short presentation and open discussion among attendees sharing their collective knowledge. It is our hope that this opportunity helps develop best practices and a network of resources, specifically related to recruiting and marketing research.
When: June 27, 2023, 9 - 10 a.m.
Where: Online
Register [external link]
Image description: Illustration of four people sitting at desks with multi-colored chat bubbles to illustrate them collaborating.
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REDCap Grand Rounds
This is a Best Practices session for Grand Rounds. Registration is required.
When: June 13, 11am - noon
Where: Online
Register for Grand Rounds [external link]
eConsent in REDCap
This level of training is appropriate for projects that have questions about collecting Electronic Informed Consent. We will be discussing the current eSignature rules and regulations, the new workflow for requesting the eConsent Extension (fee for service) and the future implementation of eConsent Extension DIY. Registration required.
When: June 28, noon - 1 p.m. EST
Where: Online
Register for eConsent in RECap [external link]
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700 Children's® – A Blog by Pediatric Experts
Nationwide Children's Hospital
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Scoliosis [external link] is defined as curvature in the spine greater than 10 degrees. Scoliosis is a relatively common condition that causes the spine to curve and rotate into a C or S shape instead of a straight line. Curves greater than 10 degrees are seen in approximately 3% of the population. Curves that progress to greater than 30 degrees are more rare (0.3%). Many times what parents think is scoliosis turns out to be spinal asymmetry (a slightly curved spine) or uneven limb lengths, but for a small number of children, the severity of the curve in their spine may require treatment.
Read More About Scoliosis in Children [external link]
Image Description: Black female doctor holding a curved spine, explaining something to a young Black female in a doctor's office. Below, Nationwide Children's Hospital logo with white, yellow, orange and blue butterflies.
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External Funding Opportunities and Events | |
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REDCap Office Hours via Zoom
When: Every Monday, 11 a.m. - 1 p.m.
Every Wednesday, 1 - 3 p.m.
Zoom Link for Office Hours [external link]
REDCap Training Resuming
The CCTS, in coordination with the Department of Research Information Technology (RIT), conducts monthly training sessions via Microsoft Teams.
There are four modules of training based on the role(s) a user will have within REDCap. Registration for each session opens two weeks prior to the session.
This level of training is appropriate for projects that have questions about collecting Electronic Informed Consent. We will be discussing the current eSignature rules and regulations, the new workflow for requesting the eConsent Extension (fee for service) and the implementation of eConsent Extension DIY.
Great for people who cannot attend the Grand Rounds session.
When: Last Wednesday of each month, noon - 1 p.m. EST
Learn More [external link]
Image Description: REDCap logo, black R wearing a red cap.
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This month's topic is REDCap Creative Uses 2.0
The monthly topics will be posted on the REDCap blog. [external link]
Advance registration is requested.
When: Second Tuesday of each month, 11 a.m. - noon
Where: Zoom
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Read about the latest translational science news, opportunities and announcements in the latest edition of the NCATS e-Newsletter and the NIH's Weekly Funding Notice.
NCATS News [external link]
NIH Funding Notice [external link]
Image Description: NIH logo. White "NIH" in gray background with blue arrow, gray text below reads "National Institutes of Health."
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Learn more about PCORI through their blog, video room, news releases and other resources.
Latest News [external link]
Image Description: pcori logo. Blue text with green and blue wisp.
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Visit our website [external link] or click on the social media icons below to be directed to our social pages (Facebook, Twitter, Youtube).
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Image Description: CCTS logo with scarlet block O above and gray text. RIT logo in black text with scarlet brackets on either side. | |
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Publications supported by the CCTS are required to cite The Ohio State University Center for Clinical and Translational Science.
Learn More [external link]
Image Description: Cite and Submit. Text below reads "Publications supported by the OSU CCTS must cite the CTSA grant number (UL1TR002733) and by law, be submitted to PubMed Center. For instructions, review the NIH Public Access Policy on the CCTS website." Below in gray text is the grant number: UL1TR002733
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