First tell tale signs and symptoms of Parkinson's aren't what you might expect

Muscle stiffness, tremors and balance problems are normally the first signs and symptoms linked to Parkinson's disease. But now, scientists in Lithuania report that that "changes in speech often occur" before the hallmark symptoms, which is why some people with early onset Parkinson's might speak quieter. Click here to learn more.

New study links multiple viral infections to a higher risk of dementia

Researchers from the National Institutes of Health (NIH) have found a correlation between having a viral illness earlier in life and an increased risk of developing neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease. The study appears in the journal Neuron. Click here to learn more.

Researchers uncover physics involved in a key process in Huntington's disease

Researchers from Princeton University have uncovered the physics of a cellular process linked to aggregation diseases, including Huntington's disease, paving the way to a deeper understanding of neurodegenerative disorders at the molecular level. The paper is published in the journal Nature Physics. Click here to learn more.

Eye movement may be a helpful measure of disease severity

Recurrent correlations across many ataxias suggest saccadic eye movements as potentially generic quantitative oculomotor outcome. To delineate the potential of these correlations as measures for clinical trials in ataxia, researchers searched articles reporting on quantitative eye movement recordings. Click here to learn more.

Dosing begins in Phase 1 study of new therapy that blocks enzyme linked to Parkinson's

Dosing has begun in a Phase 1 clinical trial of healthy volunteers to evaluate the safety and pharmacological properties of NEU-723, Neuron23’s oral investigational treatment for Parkinson’s disease. The small molecule candidate therapy is designed to block LRRK2, an enzyme coded by a gene of the same name whose mutations are one of the most common genetic causes of Parkinson’s. Click here to learn more.