The RNA Transcript, February 13th 2023 | |
U-M RNA Innovation Seminar | | |
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Why did the RNA Cross the Nanotube? Many questions and (some) answers on tunnelling-nantoube medicated RNA transfer between mammalian cells
Gal Haimovich, Ph.D.
Assistant Staff Scientist
Department of Molecular Genetics
Weizmann Institute of Science
TODAY, February 13, 2023
12:00 - 1:00 PM
Virtual Only, Zoom
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The Landscape of Mitochrondrial Translation in Health and Human Disease
James Marks, Ph.D.
Postdoctoral Fellow
RNA Molecular Biology Laboratory
National Institute of Health
TODAY, February 13, 2023
12:00 PM
BSB 1010
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Targeting Cancer with CRISPR and the Development of M-RNA Therapeutics
Mats Ljungman, Ph.D
Professor of Radiation Oncology
University of Michigan
Wednesday, February 15, 2023
12:00 - 1:00 PM
ABC Seminar Rooms BSRB
RSVP Required: Contact Stephanie Shimko sshimko@med.umich.edu
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RNA Collaborative Seminar | | |
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Tropomyosin 1-I/C co-ordinates kinesin-1 and dynein motors during oskar mRNA transport
Speaker: Simone Heber, Ph.D
Postdoctoral Fellow
The structural basis of intron branch site recognition by the human spliceosome
Speaker: Jonas Tholen, Ph.D
Postdoctoral Fellow
Moderator: Wojtek Galej, Ph.D
Wednesday, February 15, 2023.
10:00 AM
Zoom.
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U-M RNA Innovation Seminar | | |
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A Complicated Family: Conserved and Distinct Functions of tRNA Methyltransferases from Yeast to Humans
Jane Jackman, Ph.D.
Professor of Chemistry & Biochemistry
The Ohio State University
Monday, February 27, 2023
4:00 - 5:00 PM
BSRB ABC Seminars
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RNA Society Research Presentation Fellowship | | |
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The RNA Society is pleased to announce the RNA Society Research Presentation Fellowship program for 2023. This program aims to increase participation at our Annual Meeting and provides full meeting registration waivers for qualifying researchers who would otherwise be unable to attend RNA 2023 due to financial considerations.
RNA Society Research Presentation Fellowships are available to current RNA Society members presenting either an oral or poster presentation at RNA 2023 (as first or senior author). Applications will be assessed based on career stage, financial need, past meeting support, and expected total meeting costs. The Research Presentation Fellowship Selection Committee may prioritize awards according to geographical location to offset travel-associated expenses and/or to encourage participation of underrepresented scientists. Please note that submission of an application does not guarantee funding and only one Research Presentation Fellowship will be awarded per research group/lab.
Application guidelines:
- RNA Society Research Presentation Fellowships are restricted to current RNA Society members. To renew your membership, please visit the RNA Society membership page here.
- Applications require a brief Statement of Benefit, a Letter of Recommendation, an abbreviated CV, and a scientific abstract for oral or poster presentation.
- Applications for a 2023 RNA Society Research Presentation Fellowship must be submitted by February 18th, 2023 in order to be evaluated and awarded prior to the RNA 2023 oral abstract submission deadline of March 3rd, 2023. Additional applications will be accepted up until March 5th, 2023 and will be considered if allocated funds remain available; applicants will be notified by March 14th, 2023, ahead of the poster abstract submission deadlines of March 31st, 2023.
Upon notification, RNA Society Research Presentation Fellowship winners will receive complimentary registration for RNA 2023 in the form of a registration waiver code to be used at time of completing your meeting registration. We ask applicants to wait for the notification of award decisions before completing registration and paying registration fees (so as to prevent the need to refund payment).
Additional information on the RNA Society Research Presentation Fellowship program can be found on the RNA 2023 meeting website here. If you wish to apply for a fellowship, please complete the application here.
We look forward to seeing you in Singapore for RNA 2023 in May!
Best wishes,
Benoit Chabot, Chair, RNA Society Meetings Committee
Kristian Baker, CEO RNA Society
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Public Relations Specialist
We are actively looking for a candidate that is a strong writer, communicator, and experienced interviewer. Experience translating complex information for a general audience is especially important. We welcome candidates from diverse backgrounds who share our passion for developing innovative solutions. The job posting closes on 2/16/23.
Please apply here
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CALL For Poster Abstracts - RNA Center Symposium March 24th, 2023 | | |
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Poster Abstract Submission
If you are interested in presenting your most exciting, RNA-related research at the symposium, please download the attached form to a Word Document, fill it out and send it to the registration committee (c/o akintz@umich.edu) by March 3rd, 2023. Please be mindful of the deadline as no abstracts will be accepted after that date.
Registration Ends: Friday March 3rd, 2023.
Any additional questions can be addressed to Allison Kintz akintz@umich.edu
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28th Annual Meeting of the RNA Society | | |
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RNA 2023 - the 28th Annual Meeting of the RNA Society - will be held at the Suntec Convention Center in downtown Singapore from May 30th - June 4th.
Registration is now open
Look forward to seeing you there.
Best wishes,
Organizing Committee, RNA 2023
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University of Michigan Center for RNA Biomedicine's 7th Annual RNA Symposium. March 24th, 2023 | | |
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2023 Symposium
7th Annual RNA Symposium, “From Molecules to Medicines”
Friday, March 24, 2022, 8:30am – 4:00pm
A. Alfred Taubman Biomedical Science Research Bldg, Kahn Auditorium
109 Zina Pitcher Pl, Ann Arbor, Michigan
Keynote Speakers:
Steve Henikoff, PhD, Genome-wide Mapping of Protein-DNA Interaction Dynamics
Fred Hutchinson Cancer Research Center
Professor & HHMI Investigator, Basic Science Division
Jody Puglisi, PhD, Talk Title TBA
Stanford University
Professor, Department of Structural Biology
Director, Stanford Magnetic Resonance Laboratory
Geraldine Seydoux, PhD, Talk Title TBA
Johns Hopkins University
Huntington Sheldon Professor in Medical Discovery
Professor of Molecular Biology & Genetics
Amy Gladfelter, PhD, The RNA Code in Condensates
University of North Carolina at Chapel Hill
Associate Professor of Biology
Joe Wedekind, PhD, Redefining Riboswitches: Ribosome-Binding Site Sequestration is Dispensable for Gene Regulation by the Largest Group of preQ, Riboswitches
University of Rochester, Medical School
Professor of Biochemistry & Biophysics
Registration is open
Registration Ends: Friday March 10th, 2023.
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U-M Medical School - Fellowship Application | | |
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The Research Operations, Management & Strategy (ROMS) Fellowship Application
The ROMS Fellowship is a two-year, paid, full-time position at the U-M Medical School designed to transition biomedical trainees from the bench to careers in research operations and administration through a series of unit rotations, hands-on learning experiences, and direct mentorship from leaders in the field.
The application will be open January 1 – February 19, 2023.
Any additional questions can be addressed to ROMS.Fellowship@umich.edu
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OSU Nakanishi Lab - Postdoctoral Position Application | | |
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Postdoctoral Position to Explore “Tiny RNAs” in Humans
An NIH-funded postdoctoral position is available in the laboratory of Dr. Kotaro Nakanishi at The Ohio State University. The Nakanishi group studies the roles of tiny RNAs, 10 - 18 nt non coding RNAs. We recently discovered that specific 3′→5′ exonucleases trim microRNAs to
tiny RNAs. While more than 200,000 papers about microRNAs have been reported, only about 10 articles have described tiny RNAs. The physiological functions of tiny RNAs remain to be studied. My group uses molecular biology, biochemistry, RNA-seq, cell biology (confocal microscope), and structural biology (cryo-EM and crystallography) to investigate tiny RNAs. We are looking for a postdoc who explores this new world together.
Qualifications
Strong candidates are highly motivated individuals with an excellent academic track record, including first-author publication(s). Candidates should have or be in the process of completing a Ph.D. in biochemistry, molecular biology, cell biology, or structural biology. Experience in large-scale protein purification and structure determination in cryo-EM and/or X ray crystallography will be advantageous.
To apply
For more information, please visit HERE.
Questions
If you have any questions, please email nakanishi.9@osu.edu.
Recent publications:
1. Sim GY, Kehling AC, Park MS, Secor J, Divoky C, Zhang H, Malhotra N, Bhagdikar D, Abd El Wahab EW, Nakanishi K. (2022). Proc. Natl. Acad. Sci. USA.
2. Park MS, Sim GY, Kehling AC, Nakanishi K (2020). Proc. Natl. Acad. Sci. USA. 3. Park MS, Araya-Secchi R, Brackbill JA, Phan HD, Kehling AC, Abd El-Wahab EW, Dayeh DM, Sotomayor M., Nakanishi K. (2019). Molecular Cell.
4. Dayeh DM., Cantara WA., Kitzrow J., Musier-Forsyth K., Nakanishi K. (2018). Nucleic Acids
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RNA Structure and Folding Prediction Guided by Innovative Technologies - Funding Opportunities | | |
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IN-PART Discover is running a Request for Proposals (RFP) on behalf of their client, AstraZeneca. As part of their biannual CoSolve Challenge.
Deadline to register: March 10th
Registration Link Here
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6th International Course on "Post-transcriptional Gene Regulation: From Mechanisms to RNA Chemistry & Therapeutics" - Conference | | |
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The 6th international course on “Post-transcriptional gene regulation: from mechanisms to RNA chemistry and therapeutics" will take place on 24-28 April 2023 at Institut Curie in Orsay (Paris area, France).
We would greatly appreciate if you could transfer this information to your team and colleagues.
For more information, please visit the course webpage: https://training.institut-curie.org/courses/post-transcriptional-gene-regulation-2.
Deadline to register: February 17th
Registration is free but mandatory HERE.
Audience: Master and PhD students coming from European laboratories.
Candidates are selected based on their CV & a letter of motivation (mentioning the research theme and the authorization from the PI).
We would greatly appreciate if you could transfer this information to your team and colleagues.
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6th JUNIOR GROUP LEADER POSITION - Institut Curie Research Center (Osray, France) | | |
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The Research unit “Chemistry and Modelling for Biology of Cancer” (CNRS UMR9187 / Inserm U1196) at Institut Curie is recruiting a Junior Group Leader to develop chemical biology approaches related to the studies of fundamental mechanisms of cancer and/or applied to the development of novel diagnostic or therapeutic tools. The recruited group leader will benefit from the expertise of several teams present at the Orsay site of Institut Curie and working on RNA secondary structure targeting, post-transcriptional gene regulation and RNA-protein interactions.
The key criteria for the selection of candidates will be the documented quality of their scientific record, a cutting-edge innovative research project, as well as their capacity to interact with other teams at the Research Centre and Clinical Department of the Institute and beyond, and to drive developments in the field of biomedical research and treatment of cancer as the main mission of Institut Curie.
The Unit (https://institut-curie.org/unit/umr9187-u1196) is located at the Research Centre of Institut Curie in Orsay, south of Paris, and close to the Paris-Saclay research hub. The three current research groups of the Unit focus their activities on the development of small molecules to probe and control the biological activities of key nucleic acid and protein targets involved in cancer. The drug- and probe-discovery activity is sustained by molecular modelling approaches and imaging. The CMBC unit is hosting the proprietary Institut Curie–CNRS chemical library comprised of over 12,000 compounds.
The newly recruited group will benefit from the access to the local state-of-the-art research equipment and Institut Curie’s core facilities (https://institut-curie.org/network/curiecoretech). Appropriate laboratory space for 6–7 people and a start-up package will also be available.
The successful candidate should be committed to apply for third-party funding form national and international agencies, as well as for a permanent position at a French institution (CNRS, INSERM, or Paris Saclay University).
The Deadline for application is March 25, 2023.
For information & applications please contact: call.umr9187@curie.fr
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2023 Bay Area RNA Meeting - SAVE THE DATE | | |
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Hi RNA aficionado
We have identified a new date for the BARC: March 20, save the date and register! If you have already registered, no need to re-register.
Note that there is also an updated abstract submission deadline: March 01. You are free to update your submitted abstract or submit a new one. If you are registered and logged-in, you may submit or revise your speaker/poster presentation abstracts on your "My Account" profile page.
We’ve planned an engaging format with a variety of conference features:
- Back in person, on the UCSF campus
- Career development workshops
- Poster sessions organized by topic
- Option to share slides, posters, and preprints via the website
- Networking coffee and tea mingle
- Limited e-attendance seats via Zoom webinar
- Speaker and Poster Awards
If you'd like to volunteer to help chair sessions, workshops, or provide leadership opportunities, please email the organizers. Let's get the word out-- please circulate this announcement to your peers. We look forward to seeing you there.
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Our members' publications are available through Altmetrics. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.
Below are recent highlights.
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Wang, E. T., Freudenreich, C. H., Gromak, N., Jain, A., Todd, P. K., & Nagai, Y. (2023). What repeat expansion disorders can teach us about the Central Dogma. Molecular cell, 83(3), 324–329. https://doi.org/10.1016/j.molcel.2022.12.017 | |
Stephen V. Carney, Kaushik Banerjee, Anzar Mujeeb, Brandon Zhu, Santiago Haase, Maria Luisa Varela, Padma Kadiyala, Claire E. Tronrud, Ziwen Zhu, Devarshi Mukherji, Preethi Gorla, Yilun Sun, Rebecca Tagett, Felipe J. Núñez, Maowu Luo, Weibo Luo, Mats Ljungman, Yayuan Liu, Ziyun Xia, Anna Schwendeman, Tingting Qin, Maureen A. Sartor, Joseph F. Costello, Daniel P. Cahill, Pedro R. Lowenstein, Maria G. Castro; Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance. Clin Cancer Res 2023; https://doi.org/10.1158/1078-0432.CCR-22-1896 | |
McMillan, M., Gomez, N., Hsieh, C., Bekier, M., Li, X., Miguez, R., Tank, E. M. H., & Barmada, S. J. (2023). RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia. Molecular cell, 83(2), 219–236.e7. https://doi.org/10.1016/j.molcel.2022.12.019 | | | | |
