The RNA Transcript, April 4, 2022 |
|
Once again, thank you for attending the hybrid 6th Annual RNA Symposium. We were thrilled to host 150 in-person and 250 virtual attendees - from 18 different countries!
Feedback is a gift, please share yours below:
|
|
U-M Biological Chemistry Seminar |
|
|
|
Incorporation and molecular level consequences of uridine mRNA modifications
Tuesday, April 5, 2022
12:00 pm - 1:00 pm
5330 MS I
|
|
U-M Center for Cell Plasticity and Organ Design (CPOD) Cross Talk |
|
|
|
Genetic mechanisms of pediatric renovascular hypertension
Tuesday, April 5, 2022
4:00 pm - 5:00 pm
BSRB, ABC Seminar rooms ( hybrid) |
|
|
|
Wednesday, April 6, 2022
1:15 pm - 5:30 pm
Forum Hall, Palmer Commons
|
|
----Wednesday, April 6, 2022
----4:00 pm - 5:00 pm
|
|
“NERD-seq: A novel approach of Nanopore direct RNA sequencing that expands representation of non-coding RNAs”
"Dissecting the role of SINE non-coding RNAs in brain health and disease"
|
|
|
|
|
Chaperoning Protein Folding with RNA, and Fun with Foldit
Friday, April 8, 2022
12:00 pm - 1:00 pm
1640 Chemistry Dow Lab
|
|
U-M RNA Innovation Seminar |
|
|
|
Alternative structures of the SARS-CoV-2 RNA genome control gene expression and offer therapeutic strategies
Monday, April 11, 2022
4:00 pm - 5:00 pm
|
|
The International Non-coding RNA Journal Webinar |
|
|
|
RNA: The Epicentre of Genetic Information
Monday, April 11, 2022
8:00 pm - 9:00 pm
|
|
Arrowhead Pharmaceuticals / Virtual Info Session and 1:1 Interviews |
|
|
|
Arrowhead is an RNAi company looking for a Senior Analytical Development Scientist, a Senior Scientist in Discovery Chemistry, and a Senior Process Chemist CMC RSVP by April 13th
Wednesday, April 20, 2022
11:00 am Virtual Info Session
12:00 pm 1:1 Interviews
|
|
Immediate postdoc opening to incubate a CRISPR-based nucleic acid detection technology in Dr. Ailong Ke's laboratory at Cornell University |
|
There is a postdoctoral opening in Dr. Ailong Ke's laboratory at Cornell University to commercialize a CRISPR-based nucleic acid detection technology. The qualified candidate will work with Dr. Ke to secure funding through the Cornell Ignite Postdoc for Ventures program. This newly established program provides two-years of salary, research, and mentorship support to train postdocs with entrepreneurial outlooks to start technology ventures. The successful candidate will report to Dr. Ke during the first year to identify the market needs and to generate the necessary data to support product development. The candidate will then report to the director of the McGovern Incubator to bring the product to the market. Interested candidates should send your CV and names of three references through email to ak425@cornell.edu for further consideration. |
|
Multiple new postdoctoral positions in Dr. Rebecca Schulman's group at Johns Hopkins University |
|
The Schulman group at Johns Hopkins University is looking for multiple postdoctoral scholars to create new adaptive and dynamic materials and self-assembled machines by combining programmable, dynamic DNA assembly and disassembly and dynamic DNA circuits. The projects are open-ended. Work in the lab is likely to span design, quantitative modeling, and experimental characterization and analysis. Experimental techniques could include time-lapse fluorescence microscopy, TEM, and fluorescence spectroscopy. Interest in developing and making use of experimental automation for high-throughput characterization is a plus. Interested candidates can email rschulm3@jhu.edu to discuss the projects, the research group or to submit an application (please include a cover letter and CV). |
|
Pfizer is seeking proposals for the advancement of RNA therapeutics and the development of the next generation of RNA medicines |
|
Submissions invited for novel target concepts and therapeutic strategies amenable to RNA based approaches (mRNA, circular RNA, gene editing), in the following areas of interest:
- Cellular reprogramming:
- Cancer vaccines
- Infectious Disease Vaccines
- Chronic or Rare Kidney Disease (Focal Segmental Glomerulosclerosis, IgA Nephropathy, Alport Syndrome, or Autosomal Dominant Polycystic Kidney Disease)
- Rare Liver Diseases and Rare Neuromuscular Diseases
- Repeat Expansion Diseases (e.g. Huntington’s disease, Friedreich’s ataxia, ALS, myotonic dystrophy)
- Preference given to targets not amenable to small or large molecule intervention
|
|
|
|
Our members' publications are available through Altmetrics. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation. Below are recent highlights.
|
|
RNA sequencing reveals perivascular adipose tissue plasticity in response to angiotensin II, Z. Wang, H. Lu, M. Garcia-Barrio, Y. Guo, J. Zhang, Y. E. Chen, L. Chang (2022) Pharmacological Research 178. 10.1016/j.phrs.2022.106183
Keywords: RNA sequencing, Perivascular adipose tissue, Angiotensin II, MitoNEET
|
|
Joint dimension reduction and clustering analysis of single-cell RNA-seq and spatial transcriptomics data, W. Liu, X. Liao, Y. Yang, H. Lin, J. Yeong, X. Zhou, X. Shi, J. Liu (2022) Nucleic Acids Research . 10.1093/nar/gkac219
DR-SC outperforms existing clustering and spatial clustering methods: it extracts more biologically relevant features than conventional dimension reduction methods, improves clustering performance, and offers improved trajectory inference and visualization for downstream trajectory inference analyses.
|
|
THANK YOU GIVING BLUEDAY DONORS |
|
The Center for RNA Biomedicine would like to extend a huge “thank you” for your support on Giving BlueDay! Your partnership represents a commitment to creating a bright future for RNA research. Thank you! |
|
|
|
|
|
|
