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Manne Research Institute's President's Message
- Investing in Research-Driven Home Healthcare Technologies for Children
Science Showcase
- Faith Summersett Williams Receives NIAAA K23 Grant
News from the Manne Research Institute Pillars
- Most Parents Don't Ask About Firearms in the Homes Their Kids Visit
- Substance Use Emergency Department Visits Among Youth with Chronic Medical Conditions Increased During COVID-19 Pandemic
- Lurie Children’s Study to Link Genetics and Long-Term Cardiorespiratory Outcomes of Children Born Prematurely for More Precise Diagnosis and Treatment
Manne Research Institute in the Media
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Investing in Research-Driven Home Healthcare Technologies for Children
In 2023, Manne Research Institute introduced Health@Home, a research hallmark initiative focused on home healthcare delivery for children. Directed by Carolyn Foster, MD, MS, Health@Home is using research-based evidence to transform how we provide healthcare outside the walls of Lurie Children’s. Health@Home is developing, evaluating, and implementing digital healthcare tools and devices for in-home use, conducting research and clinical trials, and partnering with internal and external collaborators to share expertise and resources. I am excited to share how Carolyn, program manager Leah West, the Health@Home team, and her collaborators leverage digital technology to better support patients with complex medical conditions and their families in the in-home care setting.
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Faith Summersett Williams Receives NIAAA K23 Grant | |
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Faith Summersett Williams, PhD, MS, a behavioral scientist in The Potocsnak Family Division of Adolescent and Young Adult Medicine at Ann & Robert H. Lurie Children’s Hospital of Chicago, received a K23 grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The funds ($750,000 across the award period September 2024–August 2029) will support her research study, Adaptation and Implementation of SBIRT for Adolescents with Chronic Medical Conditions Hospitalized in Pediatric Inpatient Units.
Adolescents with a chronic medical condition have high rates of risky drinking and drug use and account for the majority of pediatric inpatient hospitalizations; however, chronic medical conditions are not routinely screened for alcohol use in pediatric inpatient settings, highlighting a major missed opportunity. Dr. Summersett Williams’s mentored research proposal will facilitate the implementation of Screening, Brief Intervention, and Referral to Treatment (SBIRT) in inpatient units within a large urban pediatric hospital, while providing preliminary data to inform the development of a highly scalable approach that can be used in pediatric hospitals across the country. SBIRT is a public health intervention and treatment approach for people with substance use disorders or those at risk of developing them.
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NEWS FROM THE RESEARCH PILLARS | |
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Parents need to know that asking about firearms is critical to their child’s safety
Over 60 percent of Illinois parents had never asked another parent about an unlocked firearm in their home before allowing their child to visit for a playdate, according to a survey from Ann & Robert H. Lurie Children’s Hospital of Chicago published in Pediatrics. Many parents reported they had not asked about firearms because it never occurred to them to do so, which highlights a critical need to raise awareness of this important safety concern.
Among children 0-14 years old, almost 20 percent of unintentional firearm-related deaths occur at a friend’s home. Furthermore, approximately 40 percent of U.S. households with children have a firearm in the home, yet only 44 percent of these households store firearms locked and unloaded, the most secure possible manner.
“Parents need to approach the topic of firearm safety in the homes their child visits in the same way they would ask other parents about supervision during playdates or similar questions related to their child’s safety,” said lead author Samaa Kemal, MD, MPH, Emergency Medicine physician at Lurie Children’s and Assistant Professor of Pediatrics at Northwestern University Feinberg School of Medicine. “Parents need to ask about the presence of firearms in the home and about secure storage methods. These discussions with other parents are crucial for prevention of children’s injury and death from improperly stored firearms.”
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Pediatric emergency department visits for substance use by youths with or without chronic medical conditions increased during the COVID-19 pandemic, with the largest increase seen in those with chronic conditions, according to a study published in JAMA Network Open. This suggests the need to improve hospital-based substance use care for these patients.
For their original investigation, the researchers sought to learn if youths with a chronic medical condition (this includes chronic conditions and complex chronic conditions) had more emergency department visits for substance use than youths without chronic conditions during the COVID-19 pandemic. The cohort study obtained data from 47 U.S. children’s hospital emergency departments that are part of the Pediatric Health Information System database between March 2018 and March 2022. The cohort included patients aged 10–18. Emergency department visits for substance use among youth increased during COVID-19, especially among youth with chronic conditions. Youths with chronic conditions and youths with complex chronic conditions had 9 times and 4 times more visits to the emergency department for substance use, respectively, than youths without these conditions. “Our findings have important implications for clinical practice and highlight the need for universal substance use screening and intervention in pediatric emergency department settings and potentially other pediatric health care settings where youths, particularly those with chronic medical conditions, seek care,” said study lead author Faith Summersett Williams, PhD, a behavioral scientist in The Potocsnak Family Division of Adolescent and Young Adult Medicine at Ann & Robert H. Lurie Children’s Hospital of Chicago and Assistant Professor of Pediatrics at Northwestern University Feinberg School of Medicine.
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NIH-funded study will use AI to identify disease subtypes
Infants born more than three months prematurely are at high risk for lung disease – called bronchopulmonary dysplasia (BPD) – that often persists through childhood, manifesting as wheezing or abnormalities in lung or heart function. Currently this imprecise diagnosis is based solely on clinical features, and it is impossible to predict how the disease will evolve in the long term, which limits opportunities for early intervention. To improve diagnosis and treatment, a new study at Ann & Robert H. Lurie Children’s Hospital of Chicago, funded by $7.6 million from the National Institutes of Health (NIH), will use AI/machine learning to identify disease subtypes that are based on genetic data and associated outcomes.
“Our study will investigate genetic influence on long-term cardiac and respiratory outcomes of premature infants, in order to identify genetic pathways that correspond to high likelihood for specific outcomes, such as asthma or cardiac dysfunction,” said Principal Investigator Aaron Hamvas, MD, Division Head of Neonatology at Lurie Children’s and Professor of Pediatrics at Northwestern University Feinberg School of Medicine. “We hope that our results will lead to genetic testing in the neonatal intensive care unit and allow earlier interventions according to the disease subtype. This advance may transform the trajectory of lung disease in premature infants.”
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MANNE RESEARCH INSTITUTE IN THE MEDIA | | | | |
