Updates in Pediatrics
Editor: Jack Wolfsdorf, MD, FAAP

header with photos of various children
August 3, 2022 | Volume 13 | Issue 31
Post-COVID-19 conditions among children 90 days after SARS-CoV-2 infection
Post-COVID-19 conditions (PCCs) have been, and continue to be described in adults (often, however, occurring in serologically-negative people!). PCCs in children remain poorly outlined and while early estimates indicated 25-58% of children may experience PCCs after an acute illness (independent of severity) later studies suggest a prevalence of 2-4%.

“A comprehensive understanding of pediatric PCCs is required to inform public health policies and guide the care of high-rick children”.

A prospective multinational cohort of 1,884 SARS-CoV-2 positive (vs. negative) children who visited an Emergency Department (ED) and completed a follow-up survey identified persistent, new or recurrent healthcare problems at 90-day post-infection.

5.8% of SARS-CoV-2 positive children report PCCs at 90 days post-infection. Most commonly reported symptoms include respiratory, fatigue or weakness. Characteristics associated with at least 1 PCC include being hospitalized (particularly with severe symptoms), having >4 symptoms at initial ED visit (e.g., fever, cough, rhinorrhea/congestion) and being 14 years of age or older.
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