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6PPD & 6PPD-quinone Guidance Now Available!

This new ITRC document provides information about 6PPD and 6PPD-q that can help inform future policies and regulations regarding these chemicals. The guide provides:

An introduction to 6PPD and 6PPD-q

Current knowledge of effects, toxicity, and physical/chemical properties of 6PPD and 6PPD-q

The occurrence, fate, and transport of 6PPD and 6PPD-q in the environment

An overview of measuring, mapping, and modeling techniques for these chemicals

Discussion of mitigation measures, solutions, policies, regulations, and laws

An overview of information gaps and research needs.

6PPD-quinone (6PPD-q) is a contaminant of emerging concern and is a transformation product of 6PPD, an antiozonant used in tires. Currently, 6PPD is used in all tires and can contaminate stormwater and surface water anywhere tires are used.


6PPD-q was identified as a chemical fatal to coho salmon in 2020. Since that time, it has been documented as acutely toxic to multiple trout species found throughout the United States. 6PPD and 6PPD-q have been found in

waterways, aquatic organisms, soils, air, and humans.


Click here to access the 6PPD Guidance Document
ITRC is a program of the Environmental Research Institute of the States (ERIS). ERIS is a 501(c)(3) organization incorporated in the District of Columbia and managed by the Environmental Council of the States (ECOS).