Dear AJPM Reader,

This year marks 40 years since AIDS was first reported in a U.S. CDC Morbidity and Mortality Weekly Report describing opportunistic pneumonia in five previously healthy young gay men living in Los Angeles. Though much progress has been made toward understanding, preventing, and treating HIV in the intervening decades, tens of thousands of new cases still occur in the U.S. each year.
 
Our latest supplement, The Evidence Base for Initial Intervention Strategies for Ending the HIV Epidemic in the U.S., from the Centers for Disease Control and Prevention's Division of HIV Prevention, includes research and commentary across the 4 key "pillars" for ending the HIV epidemic in the U.S: Diagnose, Treat, Prevent, and Respond.
 
Four articles in the supplement examine how to increase diagnosis of previously undiagnosed HIV cases. One study, for example, examined the feasibility of mail-out HVI and STI tests in Washington, DC, during the COVID-19 pandemic, finding that uptake was high.
 
Three other articles in the supplement address HIV treatment. In diverse contexts - from a citywide program in San Francisco to maximize ART initiation to using HIV telehealth in Georgia to train local health workers in providing comprehensive care - researchers found solutions to reaching those already diagnosed with HIV to ensure treatment.
 
With six articles, the largest section of the supplement emphasizes HIV prevention research. Many of these studies focus on expanding the use of PrEP among different populations, including rural Iowans and Black and Hispanic/Latino individuals throughout the U.S.
 
The final four articles in the issue discuss responses to HIV outbreaks. Through a review of the public health and medical response in West Virginia, Philadelphia, and Seattle, these articles provide examples as a guide for other jurisdictions.
 
The first mention of HIV/AIDS in AJPM was in 1986, the year after the journal's founding. In the years since, we have published more than 100 papers specifically about HIV and many others that touch on the topic. We are proud to publish research contributing to the end of  the HIV epidemic in the U.S. in what would represent an inestimable victory for public health in the 21st century.
 
We hope you find this supplement issue, as well as our November 2021 articles, to be timely, topical and informative.

Yours in prevention and health,