September 2021 | IDDRC PI NEWS
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What is Inside: In Our Blog | Featured Announcement | Core News | Meet Your Colleagues | Events |
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This new monthly communication is designed to inform you about the many resources available through your IDDRC membership, current research, upcoming events, PI happenings, and other IDDRC related news. Get to know your world-class colleagues and stay on top of our center's many activities. |
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In Memoriam: Theresa Trapilo |
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It is with deep sadness that we say good-bye to our longtime colleague and friend, Theresa Trapilo, who passed away in early September from an illness diagnosed soon after her retirement. Theresa was a beloved colleague who helped the Neurology Department, its clinical research arm and the IDDRC thrive in countless ways. All who knew her knew of her kindness, helpfulness, sense of humor, and devotion. Although no longer with us, Theresa made her mark on our center and in our hearts and we are forever grateful for having known her. |
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Promising Gene Therapy Pathways for Combating Central Nervous System Diseases by Dr. Zhigang He.
With the advent of experimental models and new technologies, tremendous progress has been made in delineating the molecular mechanisms underlying pediatric and adult neurological diseases. As a result, many new genes/pathways are suggested as potential therapeutic targets. Read more>
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Featured News | Community Outreach |
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New! Neurology Family Council (NFAC)-Research Subcommittee
The patient/family voice adds another dimension or important perspective into research. We are excited to announce that the IDDRC and NFAC have launched the NFAC Research Subcommittee as a platform for supporting 2-way communication between investigators and families. We will be organizing a “Meet the Researcher” series over the course of the year and hope that many IDDRC investigators will agree to present to this group.
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New Equipment in the Cores |
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Zeiss LSM980 with Airyscan 2.0
Coming early Winter 2022
Coming in early Winter 2022, this is the ideal platform for your confocal 4D imaging, optimized for simultaneous spectral detection of multiple weak labels up to 900 nm emission with the highest light efficiency. The Airyscan detector enables near-super resolution detail, and through multiplexing, can achieve over 45 fps for capturing fast, dynamic signals. This microscope will also be equipped for multiphoton imaging using our existing MaiTai 2-photon laser.
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Brain Vision high-density EEG system with MR scanner compatibility and MagPro X100 magnetic stimulator
Coming early Winter 2022
This cutting-edge system for noninvasive neurophysiological research includes high-density (64-128 channel) electroencephalography (EEG) along with stimulus integration software and hardware. The amplifier can be positioned in the bore of the magnetic resonance (MR) scanner, allowing integrated MR/EEG data acquisition. Additionally, the MagPro X100 magnetic stimulator and coil allows for a wide array of stimulation parameters and rates for transcranial magnetic stimulation (TMS) application.
We will update you as soon as it is ready for investigator use.
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Echo655 acoustic liquid handler
Clinical Translational Core
The ECHO 655 represents the next generation in liquid handling, supporting a variety of high throughput microplate experiments, including large-scale dose response curves, combinatorial screening, and creation of assay-ready screening plates| Enables assay miniaturization in a broad range of applications | Transfer from 384-well and 1536-well microplates | Accurate, precise, contact-free acoustic transfer in volumes as low as 2.5 nL | Transfer from Echo Qualified microplates
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Jonathan Lipton, PhD
IDDRC Member since 2017
Dr. Lipton's research centers on the molecular and cellular interfaces between circadian rhythms and neurodevelopmental and neurodegenerative disorders.
Yet he is able to take time to play the piano and do impersonations. Maybe he will tell you who if you ask him.
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April Levin, MD
IDDRC Member since 2019
Dr. Levin’s research focuses on developing biomarkers for autism and related neurodevelopmental disorders in particular in using electroencephalography (EEG).
Did you know that a patient once challenged her to a handstand competition? Guess who won?
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Seminars and Events
Sept 27: Reza Sharif, PhD, "Central and Peripheral Mechanisms of Mechanical Allodynia," McGill Univ
Oct 6: Human Neuron Core | ICCTR Core Webinar Series | Register
Oct 27: Animal Behavior and Physiology | ICCTR Core Webinar Series | Register
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OCTOBER National Awareness Days
Rett Syndrome Awareness Month
Children’s Health Day, 10/4
Mental Illness Awareness Week, 10/5-10/10
Phelan McDermid Awareness, 10/22
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IDDRC Member Happenings and Kudos |
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Congratulations to Dr. Chris Walsh for receiving The Gruber Neuroscience Prize for his groundbreaking work on how genes and molecular mechanisms regulate the development of the human cerebral cortex. The award, along with a $500,000 prize, will be formally presented to Dr. Walsh in November at the annual meeting of the Society for Neuroscience.
Kudos to Dr. Nicole Ullrich for completing the American Academy of Neurology's "Women Leading in Neurology" leadership program.
Congratulations to the BCH Rett Team! Boston Children’s Hospital is one of 15 institutions across the U.S. that has received the International Rett Syndrome Foundation (IRSF)’s Center of Excellence designation. The award recognizes Boston Children’s continued dedication to providing best-in-class clinical care for Rett syndrome, a rare neurological and developmental disorder.
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We want to hear from you
- Interested in submitting a blog article?
- Have any news that you would like to share?
- Have suggestions for other types of information that you would like to see here?
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Remember to Cite the IDDRC or its Cores in your Publications
IDDRC funded by NIH P50 HD105351
Or
We thank the IDDRC's {enter name of core here} funded by NIH P50 HD105351
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