Ready, Set,
November 27, 2019 | 6.0
Dear Colleagues,

It’s been another exciting and successful month since the last update. Check out what Department investigators have accomplished, from Shark Tanks to Young investigator Awards to Honorary Life Awards to BCRISP and much more! 

Best,

Danny
Awards & Grants
Charles Serhan first discovered Resolvin E1, the active agent in TP-317. Thetis Pharmaceuticals recently received funding from the Crohn's & Colitis Foundation's IBD Ventures program to support development of TP-317, a first-in-class, oral therapy for inflammatory bowel disease (IBD).

Learn more: bit.ly/2rnY4Jb
Wei Tao was awarded the Behrakis Heart and Vascular Center Junior Faculty Award from Brigham Health for $200,000 over two years. The mission of this award is to provide the brightest, most promising young physician–researchers the support needed to conduct pilot studies and collect the critical data needed to pursue funding from the NIH and other agencies.
Scott Segal and Chris Connor’s research proposal titled “ Development of machine learning algorithms to predict difficult airway management ” was selected by the Anesthesia Patient Safety Foundation (APSF) Scientific Evaluation Committee for the APSF/Medtronic Research Award .
Chris Connor and Jason Yong were finalists in the fall Shark Tank competition .

Chris's project was titled "Imaging opioid effects, tolerance and addiction in C. elegans"

Jason Yong's project was titled "Smart Pill Dispenser to Enhance Opioid Compliance and Patient Outcomes"
Dirk Varelmann was selected as a BCRISP finalist for his project on “Preventing Cardiac Surgery Readmission with Patient Activity Tracking Technology,” and will receive funding for FY20.
Sungwhan Oh received the Eicosanoid Research Foundation Young Investigator Award at the 16th International Conference on Bioactive Lipids in Cancer, Inflammation, and Related Diseases .
St. Petersburg, FL, October 20-23, 2019

Sungwhan's group also received an investigator-initiated research award from Department of defense (DOD-IIRA) entitled ‘Gut Symbiotic Lipid A Family: Structures and Immunomodulation in IBD’. This award supports a 3-year, multi-PI project (collaborator: Dr. Dennis Kasper at Harvard Medical School), investigating structural and chemical variety of lipid A molecules originated from gut symbiotic microbial species.
September 2019
Charlotte Jouvene received the Research Excellence Award at Discover Brigham 2019. She presented her work titled " Resolvin D4 Attenuates the Severity of Pathological Deep Vein Thrombosis in Mice."
November 2019
Society for Leukocyte Biology 52nd Annual Meeting Award Recipients
Boston, November 15-18, 2019
Charles Serhan received the S ociety for Leukocyte Biology Honorary Life Award at their 52nd Annual Meeting in Boston.
Jouvene CC, Libreros S, de la Rosa X, Norris PC, Serhan CN. Resolvin D4: biosynthesis and actions in mice vasculature (#100).
Charlotte Jouvene, Junior Faculty/Postdocs Presidential Award Finalist.
 
Sansbury BE, Li X, Wong B, Patsalos A, Giannakis N, Nagy L, Spite M. Resolvin D1 Engages Myeloid Cell-Dependent Revascularization During Ischemia via Its Receptor, ALX/FPR2 (#107).
1st Place, Poster Flash Talk.
 
Bruggeman TR, Krishnamoorthy N, Duvall MG, Abdulnour RE, Filippakis H, Levy BD. Phospholipid Phosphatase 6 Regulates Phagocyte Function and Immune Responses (#LB01).
Poster Award.
 
Tavares L, Bruggeman TR, Rezende RM, Machado MG, Abdulnour RE, Norris P, Kilic A, Garcia CC, Serhan CN, Teixeira MM, Levy BD. Maresin Conjugates in Tissue Regeneration (MCTRs) Improve Post-influenza Pneumococcal Pneumonia by Modulation of Macrophage Phenotype (#LB02).
Poster Award.
 
Walker KH, Krishnamoorthy N, Brüggeman TR, Norris PC, Serhan CN, Levy BD. Protectin D1 and Protectin Conjugate for Tissue Regeneration 1 Regulate Lung Inflammation and Viral Load During Respiratory Syncytial Virus Infection (#LB08).
Poster Award.
"Our Scientists are Working on It"
I deas Requested!
As you may have seen on the rotating flat screens throughout the hospital, Brigham Health has been executing a new research campaign since January of 2019. They are looking for new and exciting material to use for their “ Our Scientists are Working on It ” series.  

They need short, punchy, eye-catching one-liners about BWH research, highlighting the translational impact of their work .

Ex. " Can viruses be used to treat brain cancer? Our scientists are working on it "

Every suggestion posted will highlight the specific investigators working on the issue, so this is nice opportunity to promote our research faculty and the transformative work they are doing .

Please reach out to Claire O'Brien with any questions you may have!
Please save the date for Saturday, April 11 2020 for our annual Research Retreat. Details are subject to change. More to come!
Featured Investigator
Phillip Lirk
Dr. Lirk is an Associate Professor of Anesthesia at Harvard Medical School and has an almost insatiable appetite for research and adventure. He grew up and attended Elementary and High School in a small village in the mountains of Austria, Saalfelden. His interest in scientific research was peaked at the age of 15. As a language student in Cambridge he became fascinated by the excitement of academic life. A city in which everything was so focused on academics and knowledge was unlike anything he had seen before. After completing a year as a conscript in the Austrian Army he subsequently went on to do medical school in Innsbruck, Austria, finishing in the Spring of 2002. Later, when he was working as an Anatomy Tutor it was time to spring into action. Next to student courses, Tutors also helped in cadaver courses for different specialties, among them Anesthesia. During one of these courses, participants and teachers were arguing whether the ligamentum flavum may have gaps that can theoretically make the Loss-of-Resistance less perceptible. When he read up after the course, he did not find a good study on this subject, so together with an Anatomist, they did the study. The result was a series of three manuscripts on the ligaments and the loss of resistance.  

His manuscripts on Loss-of-Resistance did not go unnoticed by his Chair and later when there was a search for a resident to go to Milwaukee to do Pain and Regional Anesthesia research, Dr. Lirk was asked to go. He had a wonderful time in the beautiful Midwest in the lab of Quinn Hogan, a BWH alum as well as Peter Gerner. Now 16 years ago, these were his first Brigham contacts. Never had he imagined he would one day work here too. He returned to Innsbruck from Milwaukee to finish residency in 2010. After residency, he completed a peculiar degree which only survives in Austria, Germany, Switzerland, France and Poland called “Habilitation”. It formally qualifies physicians and scientists to hold their own lectures, take exams and perform independent research at a public University. There is not a real corresponding degree in the US, but for Middle Europe it is a big deal and coincidentally his first son was born just a few weeks before the ceremony. In the summer of the same year he was asked to come work at the University of Amsterdam. Both he and his wife thought that this would be a great adventure and they emigrated shortly after, living in Amsterdam for six and a half years. There they had two more sons and he enrolled in a Ph.D. program which he finished in 2014. Amsterdam was a wonderful city to live in, so international just how they had hoped it would be. The only thing to top that would be the United States. Then in 2016 the discussion first arose about the possibility of joining this great Department at BWH, it did not take long to decide to move to Boston for good. Now they are here and very happy. Recently, two wonderful babies and a puppy joined the family and the older kids have taken up basketball and baseball so there are always things to do and kids with plans.  

In the bigger academic picture, Dr. Lirk hopes to contribute to a better understanding of phenomena we encounter in clinical practice, such as “why is the loss of resistance sometimes a little odd?” or “why do nerve blocks last longer in diabetic neuropathic nerves” or “how do local anesthetics sometimes cause nerve damage”. Outside of the Brigham, Dr. Lirk enjoys spending time with family (95%), friends (5%) and his resolution for the new year is to play more sports. 
Department-Wide Research Education Initiative Grand Rounds
Finding Funding
Are you considering submitting a grant?
Please reach out to Rachel Abrams for a list of required documents and to get the process started.
Featured Opportunities
Spring 2020 BRI Health & Technology Innovation Fund 
Letter of Intent Deadline Monday, January 13, 2020. 11:00 pm
Funding : $50,000
Eligibility : BWH 
Brigham & Women’s Hospital will host its bi-annual Shark Tank in May 2020 to fund innovative and high-risk/high-impact projects in the basic, clinical, digital and translational realms through its Health & Technology Innovation Awards. Sponsored by the Brigham Research Institute (BRI) and the BWH Health & Technology Subcommittee, these awards aim to advance projects that have the potential to make an impact in one or more of the following domains – biomedical research, healthcare delivery, the generation of new companies/products/services, cost savings, care quality and provider burnout.
Anesthesiology Department Seed funding
Deadline : Rolling
Funding : up to $10,000 
Eligibility : Lecturer, Instructor, Assistant, or Associate Professor at the time of award funding
•   Goal: Support clinical, translational, or basic science research and project development
•   Prerequisites: 
–   Grantee should have a mentoring plan (senior mentor or mentoring team in area of proposed investigation)
–   Grantee should have a career development plan
Up to 5 seed grants will be awarded in 2019. Grant recipients are required to present their work to the Research Leadership Committee before the start of the project and to the Department at the conclusion of their grant.

Family Care Travel Award
Deadline : Rolling
Funding : up to $750 (lifetime limit of 2 awards will apply to each applicant)
The Center for Diversity & Inclusion, with the support of the Brigham and Women’s Physician’s Organization and the Biomedical Research Institute, is pleased to announce the Family Care Travel Award to assist faculty who are caring for a dependent family member at home. The Award will provide financial support to defray some of the costs of traveling with dependents, or extra care at home, while traveling for professional meetings critical to promoting the advancement of early career scholars with familial obligations. 
Helpful Resources
For guidance and advice on the research process and resources, contact Sarah Corey.

For a Department of Anesthesiology Biostatistical consult, please follow this link or send an email to Kara Fields.
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Publications
Addressing Racial and Ethnic Disparities in Pain Management in the Midst of the Opioid Crisis.  Bateman BT , Carvalho B.
Obstet Gynecol. 2019 Nov 4. doi: 10.1097/AOG.0000000000003590. [Epub ahead of print] No abstract available.

Average and time-specific maternal prenatal inflammatory biomarkers and the risk of labor epidural associated fever.
Arce DY , Bellavia A, Cantonwine DE, Napoli OJ, Meeker JD, James-Todd T, McElrath TF, Tsen LC.
PLoS One. 2019 Nov 5;14(11):e0222958. doi: 10.1371/journal.pone.0222958. eCollection 2019.

In Response.
Urman RD , Chung F, Gan TJ.
Anesth Analg. 2019 Oct 31. doi: 10.1213/ANE.0000000000004504. [Epub ahead of print] No abstract available.

Acute Kidney Injury after Surgery: Where Does the Journey Lead?
Gelman S .
Anesthesiology. 2019 Oct 25. doi: 10.1097/ALN.0000000000003027. [Epub ahead of print] No abstract available.

Twenty-Three-Hour-Stay Colectomy Without Increased Readmissions: An Analysis of 1905 Cases from the National Surgical Quality Improvement Program.
Saadat LV, Mahvi DA, Jolissaint JS, Gabriel RA, Urman R , Gold JS, Whang EE.
World J Surg. 2019 Nov 4. doi: 10.1007/s00268-019-05257-8. [Epub ahead of print]

Effects of Low-Fat and High-Fat Meals, with and without Dietary Fiber, on Postprandial Endothelial Function, Triglyceridemia, and Glycemia in Adolescents.
Whisner CM, Angadi SS, Weltman NY , Weltman A, Rodriguez J, Patrie JT, Gaesser GA.
Nutrients. 2019 Nov 2;11(11). pii: E2626. doi: 10.3390/nu11112626.

Mind-Body Therapies for Opioid-Treated Pain: A Systematic Review and Meta-analysis.
Garland EL, Brintz CE, Hanley AW, Roseen EJ, Atchley RM , Gaylord SA, Faurot KR, Yaffe J, Fiander M, Keefe FJ.
JAMA Intern Med. 2019 Nov 4. doi: 10.1001/jamainternmed.2019.4917. [Epub ahead of print]

CLINICAL PRACTICE GUIDELINES FOR THE PERIOPERATIVE NUTRITION, METABOLIC, AND NONSURGICAL SUPPORT OF PATIENTS UNDERGOING BARIATRIC PROCEDURES - 2019 UPDATE: COSPONSORED BY AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS/AMERICAN COLLEGE OF ENDOCRINOLOGY, THE OBESITY SOCIETY, AMERICAN SOCIETY FOR METABOLIC & BARIATRIC SURGERY, OBESITY MEDICINE ASSOCIATION, AND AMERICAN SOCIETY OF ANESTHESIOLOGISTS.
Mechanick JI, Apovian C, Brethauer S, Garvey WT, Joffe AM, Kim J, Kushner RF, Lindquist R, Pessah-Pollack R, Seger J, Urman R , Adams S, Cleek JB, Correa R, Figaro MK, Flanders K, Grams J, Hurley DL, Kothari S, Seger MV, Still CD.
Endocr Pract. 2019 Nov 4. doi: 10.4158/GL-2019-0406. [Epub ahead of print]

Resolution metabolomes activated by hypoxic environment.
Norris PC , Libreros S , Serhan CN .
Sci Adv. 2019 Oct 23;5(10):eaax4895. doi: 10.1126/sciadv.aax4895. eCollection 2019 Oct.

The Impact of Epidural Analgesia on Perioperative Morbidity or Mortality After Open Abdominal Aortic Aneurysm Repair.
Greco KJ, Brovman EY, Nguyen LL, Urman RD .
Ann Vasc Surg. 2019 Oct 28. pii: S0890-5096(19)30901-X. doi: 10.1016/j.avsg.2019.10.054. [Epub ahead of print]

Factors Associated With Optimal Follow-up in Women with BI-RADS 3 Breast Findings.
Lacson R, Wang A, Cochon L, Giess C, Desai S , Eappen S , Khorasani R.
J Am Coll Radiol. 2019 Oct 26. pii: S1546-1440(19)31191-3. doi: 10.1016/j.jacr.2019.10.003. [Epub ahead of print]

Concordance in advance care preferences among high-risk surgical patients and surrogate health care decision makers in the perioperative setting.
Udelsman BV, Govea N, Cooper Z, Chang DC, Bader A , Meyer MJ.
Surgery. 2019 Oct 23. pii: S0039-6060(19)30620-8. doi: 10.1016/j.surg.2019.08.013. [Epub ahead of print]

The Association Between Potential Opioid-Related Adverse Drug Events and Outcomes in Total Knee Arthroplasty: A Retrospective Study.
Jones MR, Kramer ME , Beutler SS , Kaye AD, Rao N, Brovman EY , Urman RD .
Adv Ther. 2019 Oct 29. doi: 10.1007/s12325-019-01122-1. [Epub ahead of print]

The Promise and Perils of Big Data in the Clinical Neurosciences.
Glezerson BA , Flexman AM.
J Neurosurg Anesthesiol. 2019 Oct 23. doi: 10.1097/ANA.0000000000000659. [Epub ahead of print] No abstract available.

The demographics of persistent opioid consumption following limb amputation.
Steen T , Lirk PB , Sigurdsson MI.
Acta Anaesthesiol Scand. 2019 Oct 24. doi: 10.1111/aas.13497. [Epub ahead of print]

Comparing Outcomes and Costs of Surgical Patients Treated at Major Teaching and Nonteaching Hospitals: A National Matched Analysis.
Silber JH, Rosenbaum PR, Niknam BA, Ross RN, Reiter JG, Hill AS, Hochman LL, Brown SE, Arriaga AF , Kelz RR, Fleisher LA.
Ann Surg. 2019 Oct 15. doi: 10.1097/SLA.0000000000003602. [Epub ahead of print]

In Response.
Urman RD , Rajan N, Belani K, Gayer S, Joshi GP.
Anesth Analg. 2019 Oct 15. doi: 10.1213/ANE.0000000000004449. [Epub ahead of print] No abstract available.

Safe Sedation Re-examined: Comparing the Respiratory Effects of Dexmedetomidine and Propofol.
Wanderer JP , Rathmell JP .
Anesthesiology. 2019 Nov;131(5):A19. doi: 10.1097/ALN.0000000000003008. No abstract available.

The American Board of Anesthesiology's Staged Examination System and Performance on the Written Certification Examination After Residency.
Zhou Y, Sun H, Macario A, Martin DE, Rathmell JP , Warner DO.
Anesth Analg. 2019 Nov;129(5):e159-e162. doi: 10.1213/ANE.0000000000004250 .

Author Correction: Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease.
Krashia P, Cordella A, Nobili A, La Barbera L, Federici M, Leuti A, Campanelli F, Natale G, Marino G, Calabrese V, Vedele F, Ghiglieri V, Picconi B, Di Lazzaro G, Schirinzi T, Sancesario G, Casadei N, Riess O, Bernardini S, Pisani A, Calabresi P, Viscomi MT, Serhan CN , Chiurchiù V , D'Amelio M, Mercuri NB.
Nat Commun. 2019 Oct 14;10(1):4725. doi: 10.1038/s41467-019-12538-2.

Potential opioid-related adverse events following spine surgery in elderly patients.
Jones MR, Brovman EY , Novitch MB, Rao N, Urman RD .
Clin Neurol Neurosurg. 2019 Nov;186:105550. doi: 10.1016/j.clineuro.2019.105550. Epub 2019 Oct 3.

Clinical Practice Improvement: Mind the Gap or Fall into the Chasm.
Schwann NM, Engstrom RH, Shernan SK , Bollen BA.
J Cardiothorac Vasc Anesth. 2019 Nov;33(11):2900-2901. doi: 10.1053/j.jvca.2019.06.019. No abstract available.

Iatrogenic common carotid pseudoaneurysm in a neonate.
Qiu Y, Yao D .
Paediatr Anaesth. 2019 Oct;29(10):1067-1068. doi: 10.1111/pan.13733. No abstract available.

Corrigendum to 'State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018' (Br J Anaesth 2019; 123: 464-478).
Mahanna-Gabrielli E, Schenning KJ, Eriksson LI, Browndyke JN, Wright CB, Culley DJ , Evered L, Scott DA, Wang NY, Brown CH 4th, Oh E, Purdon P, Inouye S, Berger M, Whittington RA, Price CC, Deiner S.
Br J Anaesth. 2019 Oct 4. pii: S0007-0912(19)30689-0. doi: 10.1016/j.bja.2019.09.014. [Epub ahead of print] No abstract available.

Biosynthetic metabolomes of cysteinyl-containing immunoresolvents.
Jouvene CC , Shay AE , Soens MA , Norris PC , Haeggström JZ, Serhan CN .
FASEB J. 2019 Oct 5:fj201902003R. doi: 10.1096/fj.201902003R. [Epub ahead of print]

A tribute to Gerald Weissmann (1930-2019).
Abramson SB, Anderson PJ, Buyon JP, Cronstein BN, Pederson T, Philips MR, Serhan CN .
J Clin Invest. 2019 Nov 1;129(11):4553-4555. doi: 10.1172/JCI133490. No abstract available.

Patient Satisfaction: Measuring the Association Between Anesthetic Management and Patient Experience.
Urman RD , Gan TJ.
Anesth Analg. 2019 Oct;129(4):918-920. doi: 10.1213/ANE.0000000000004361. No abstract available.

Does bedtime matter among patients with chronic pain? A longitudinal comparison study.
McHugh RK, Edwards RR , Ross EL , Jamison RN .
Pain Rep. 2019 May 9;4(3):e747. doi: 10.1097/PR9.0000000000000747. eCollection 2019 May-Jun.

Screening and Diagnosing Frailty in the Cardiac and Noncardiac Surgical Patient to Improve Safety and Outcomes.
Acosta A , Garzon MP, Urman RD .
Int Anesthesiol Clin. 2019 Summer;57(3):111-122. doi: 10.1097/AIA.0000000000000239. No abstract available.

The role of the American Society of anesthesiologists physical status classification in predicting trauma mortality and outcomes.
Kuza CM, Matsushima K, Mack WJ, Pham C, Hourany T, Lee J, Tran TD, Dudaryk R, Mulder MB, Escanelle MA, Ogunnaike B, Ahmed MI, Luo X, Eastman A, Imran JB, Melikman E, Minhajuddin A, Feeler A, Urman RD , Salim A, Spencer D, Gabriel V, Ramakrishnan D, Nahmias JT.
Am J Surg. 2019 Sep 24. pii: S0002-9610(19)30254-5. doi: 10.1016/j.amjsurg.2019.09.019. [Epub ahead of print]

A Chronology for the Identification and Disclosure of Adverse Effects of Succinylcholine.
Huang L, Sang CN , Desai MS.
J Anesth Hist. 2019 Jul;5(3):65-84. doi: 10.1016/j.janh.2018.07.003. Epub 2018 Jul 29.

Risk of Major Complications After Perioperative Norepinephrine Infusion Through Peripheral Intravenous Lines in a Multicenter Study.
Pancaro C, Shah N, Pasma W, Saager L, Cassidy R, van Klei W, Kooij F, Vittali D, Hollmann MW, Kheterpal S, Lirk P .
Anesth Analg. 2019 Sep 27. doi: 10.1213/ANE.0000000000004445. [Epub ahead of print]

A Tale of Different Populations: Disparities in Obstetric Anesthesia.
Wanderer JP, Rathmell JP .
Anesthesiology. 2019 Oct;131(4):A23. doi: 10.1097/ALN.0000000000002979. No abstract available.

Trends in Postpartum Hemorrhage in the United States From 2010 to 2014.
Reale SC , Easter SR, Xu X, Bateman BT , Farber MK .
Anesth Analg. 2019 Sep 18. doi: 10.1213/ANE.0000000000004424. [Epub ahead of print]

Understanding Debriefing: A Qualitative Study of Event Reconstruction at an Academic Medical Center.
Sweeney RE, Clapp JT, Arriaga AF , Muralidharan M, Burson RC 2nd, Gordon EKB, Falk SA, Baranov DY, Fleisher LA.
Acad Med. 2019 Sep 17. doi: 10.1097/ACM.0000000000002999. [Epub ahead of print]

Immunoresolvent Resolvin D1 Maintains the Health of the Ocular Surface.
Dartt DA, Hodges RR, Serhan CN .
Adv Exp Med Biol. 2019;1161:13-25. doi: 10.1007/978-3-030-21735-8_3. Review.

Disparities in Acute Pain Treatment by Cognitive Status in Older Adults with Hip Fracture.
Chang AK, Edwards RR , Morrison RS, Argoff C, Ata A, Holt C, Bijur PE.
J Gerontol A Biol Sci Med Sci. 2019 Sep 27. pii: glz216. doi: 10.1093/gerona/glz216. [Epub ahead of print]

The Association Between Potential Opioid-Related Adverse Drug Events and Outcomes in Colorectal Surgery.
Homsi J , Brovman EY , Rao N, Whang EE, Urman RD .
J Laparoendosc Adv Surg Tech A. 2019 Sep 26. doi: 10.1089/lap.2019.0408. [Epub ahead of print]

Endogenous Specialized Proresolving Mediator Profiles in a Novel Experimental Model of Lymphatic Obstruction and Intestinal Inflammation in African Green Monkeys.
Becker F, Romero E, Goetzmann J, Hasselschwert DL, Dray B, Vanchiere J, Fontenot J, Yun JW, Norris PC , White L, Musso M, Serhan CN , Alexander JS, Gavins FNE.
Am J Pathol. 2019 Oct;189(10):1953-1972. doi: 10.1016/j.ajpath.2019.05.013.

The Impact of a Daily Yoga Program for Women with Fibromyalgia.
Lazaridou A , Koulouris A , Dorado K , Chai P, Edwards RR , Schreiber KL .
Int J Yoga. 2019 Sep-Dec;12(3):206-217. doi: 10.4103/ijoy.IJOY_72_18.

The relationship between patient factors and the refusal of analgesics in adult Emergency Department patients with extremity injuries, a case-control study.
Ridderikhof ML, Lodder DV, Van Dieren S, Lirk P , Goddijn H, Goslings JC, Hollmann MW.
Scand J Pain. 2019 Sep 19. pii: /j/sjpain.ahead-of-print/sjpain-2019-0077/sjpain-2019-0077.xml. doi: 10.1515/sjpain-2019-0077. [Epub ahead of print]

Adipocytes promote ovarian cancer chemoresistance.
Yang J, Zaman MM, Vlasakov I , Roy R, Huang L, Martin CR, Freedman SD, Serhan CN , Moses MA.
Sci Rep. 2019 Sep 16;9(1):13316. doi: 10.1038/s41598-019-49649-1.

Standardized outcomes in reproductive cardiovascular care: The STORCC initiative.
Valente AM, Landzberg MJ, Gauvreau K, Egidy-Assenza G, Barker N, Partington S, Morgan RB, Harmon AJ, Hickey K, Mullen MP, Carabuena JM , O'Gara P, Economy KE; STORCC Investigators.
Am Heart J. 2019 Aug 9;217:112-120. doi: 10.1016/j.ahj.2019.07.015. [Epub ahead of print]

Beyond Anesthesia Toxicity: Anesthetic Considerations to Lessen the Risk of Neonatal Neurological Injury.
McCann ME, Lee JK, Inder T .
Anesth Analg. 2019 Nov;129(5):1354-1364. doi: 10.1213/ANE.0000000000004271.

Academic bullies leave no trace.
Mahmoudi M .
Bioimpacts. 2019;9(3):129-130. doi: 10.15171/bi.2019.17. Epub 2019 May 26.

AAAPT Diagnostic Criteria for Acute Pain Following Breast Surgery.
Schreiber KL , Belfer I, Miaskowski C, Schumacher M, Stacey BR, Van De Ven T.
J Pain. 2019 Sep 5. pii: S1526-5900(19)30790-4. doi: 10.1016/j.jpain.2019.08.008. [Epub ahead of print]

Nanoscale Technologies for Prevention and Treatment of Heart Failure: Challenges and Opportunities.
Hajipour MJ, Mehrani M, Abbasi SH, Amin A, Kassaian SE, Garbern JC, Caracciolo G, Zanganeh S, Chitsazan M, Aghaverdi H , Kamali Shahri SM , Ashkarran A , Raoufi M, Bauser-Heaton H, Zhang J, Muehlschlegel JD , Moore A, Lee RT, Wu JC, Serpooshan V, Mahmoudi M .
Chem Rev. 2019 Sep 6. doi: 10.1021/acs.chemrev.8b00323. [Epub ahead of print]

Online teletherapy for chronic pain: A systematic review.
Mariano TY, Wan L , Edwards RR , Jamison RN .
J Telemed Telecare. 2019 Sep 5:1357633X19871746. doi: 10.1177/1357633X19871746. [Epub ahead of print] No abstract available.

A Multicenter, Randomized Controlled Trial of Perioperative Palliative Care Surrounding Cancer Surgery for Patients and Their Family Members (PERIOP-PC).
Aslakson RA, Chandrashekaran SV, Rickerson E , Fahy BN, Johnston FM, Miller JA, Conca-Cheng A, Wang S, Morris AM, Lorenz K, Temel JS, Smith TJ.
J Palliat Med. 2019 Sep;22(S1):44-57. doi: 10.1089/jpm.2019.0130.

Opioid Prescribing After Surgery in the United States, Canada, and Sweden.
Ladha KS, Neuman MD, Broms G, Bethell J, Bateman BT , Wijeysundera DN, Bell M, Hallqvist L, Svensson T, Newcomb CW, Brensinger CM, Gaskins LJ, Wunsch H.
JAMA Netw Open. 2019 Sep 4;2(9):e1910734. doi: 10.1001/jamanetworkopen.2019.10734.

Office-based anesthesia: an update on safety and outcomes (2017-2019).
Seligson E , Beutler SS , Urman RD .
Curr Opin Anaesthesiol. 2019 Dec;32(6):756-761. doi: 10.1097/ACO.0000000000000789.

Reply to "Postoperative Delirium and EEG Monitoring".
Susano MJ, Crosby G , Culley DJ .
J Neurosurg Anesthesiol. 2019 Oct;31(4):447-448. doi: 10.1097/ANA.0000000000000621. No abstract available.

Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease.
Krashia P, Cordella A, Nobili A, La Barbera L, Federici M, Leuti A, Campanelli F, Natale G, Marino G, Calabrese V, Vedele F, Ghiglieri V, Picconi B, Di Lazzaro G, Schirinzi T, Sancesario G, Casadei N, Riess O, Bernardini S, Pisani A, Calabresi P, Viscomi MT, Serhan CN , Chiurchiù V , D'Amelio M, Mercuri NB.
Nat Commun. 2019 Sep 2;10(1):3945. doi: 10.1038/s41467-019-11928-w. Erratum in: Nat Commun. 2019 Oct 14;10(1):4725.

Overnight call and sleep deprivation - A demand for action.
Tsai MH, Urman RD , Adams DC.
J Clin Anesth. 2019 Aug 29;60:74-75. doi: 10.1016/j.jclinane.2019.08.046. [Epub ahead of print] No abstract available.

A Novel 3-Dimensional Approach for the Echocardiographic Evaluation of Mitral Valve Area After Repair for Degenerative Disease.
Karamnov S , Burbano-Vera N , Shook DC , Fox JA , Shernan SK .
Anesth Analg. 2019 Aug 22. doi: 10.1213/ANE.0000000000004379. [Epub ahead of print]

Scanning for Experts: Practical Approaches to Incorporate Ultrasound Use in the ICU and Enhance an Ultrasound Educational Program.
Sternschein RM, Gay EB, Palmer LJ , Hayes MM.
Ann Am Thorac Soc. 2019 Aug 27. doi: 10.1513/AnnalsATS.201904-334PS. [Epub ahead of print] No abstract available.

Potential role of pharmacogenomics testing in the setting of enhanced recovery pathways after surgery.
Awad H, Ahmed A, Urman RD , Stoicea N, Bergese SD.
Pharmgenomics Pers Med. 2019 Jul 26;12:145-154. doi: 10.2147/PGPM.S198224. eCollection 2019.

The Safety and Efficacy of Tranexamic Acid in Adult Spinal Deformity Surgery: A Systematic Review and Meta-Analysis.
Hariharan D, Mammi M, Daniels K, Lamba N, Petrucci K, Cerecedo-Lopez CD, Doucette J, Hulsbergen AFC, Papatheodorou S, Aglio LS , Smith TR, Mekary RA, Zaidi H.
Drugs. 2019 Oct;79(15):1679-1688. doi: 10.1007/s40265-019-01185-y. Review.

Online group pain management for chronic pain: Preliminary results of a novel treatment approach to teletherapy.
Mariano TY, Wan L , Edwards RR , Lazaridou A , Ross EL , Jamison RN .
J Telemed Telecare. 2019 Aug 20:1357633X19870369. doi: 10.1177/1357633X19870369. [Epub ahead of print] No abstract available.

Pulmonary thromboembolism from extracorporeal life support (ECLS) cannula-associated Thrombus.
Elhassan A, Dimitrova GT, Urman RD , Cornett EM, Kaye AD.
J Clin Anesth. 2019 Aug 17;60:6-7. doi: 10.1016/j.jclinane.2019.08.002. [Epub ahead of print] No abstract available.

Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity.
Sharma M, Schlegel M, Brown EJ, Sansbury BE , Weinstock A, Afonso MS, Corr EM, van Solingen C, Shanley LC, Peled D, Ramasamy R, Schmidt AM, Spite M , Fisher EA, Moore KJ.
Immunometabolism. 2019;1(2). pii: e190010. doi: 10.20900/immunometab20190010. Epub 2019 Aug 7.

Anesthetic Management During Electroconvulsive Therapy in Children: A Systematic Review of the Available Literature.
Stein ALS, Sacks SM , Roth JR, Habis M, Saltz SB, Chen C.
Anesth Analg. 2019 Aug 14. doi: 10.1213/ANE.0000000000004337. [Epub ahead of print]

In Response.
Berger M, Angst MS, Culley DJ , Price CE, Scott DA, Whittington RA, Eckenhoff RG; Perioperative Neurotoxicity Working Group.
Anesth Analg. 2019 Sep;129(3):e112-e113. doi: 10.1213/ANE.0000000000004300. No abstract available.

In Response.
Bradley JA, Urman RD , Yao D .
Anesth Analg. 2019 Sep;129(3):e110. doi: 10.1213/ANE.0000000000004286. No abstract available.

Do You Really Mean It? Assessing the Strength, Frequency, and Reliability of Applicant Commitment Statements During the Anesthesiology Residency Match.
Moran KR, Schell RM, Smith KA, Abdel-Rasoul M, Lekowski RW Jr , Rankin DD, DiLorenzo A, McEvoy MD.
Anesth Analg. 2019 Sep;129(3):847-854. doi: 10.1213/ANE.0000000000004136.

Moore DJ, Meints SM, Lazaridou A, Johnson D, Franceschelli O, Cornelius M,
Schreiber K , Edwards RR . The Effect of Induced and Chronic Pain on Attention. J
Pain. 2019 Nov;20(11):1353-1361. doi: 10.1016/j.jpain.2019.05.004. Epub 2019 May
9. PubMed PMID: 31077797.
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