February 1, 2020
While we wait for Phil's forecast, let's talk about kidney health - (riveting, right?)
This week at Wondrous Roots: Gentleman with diabetes, high blood pressure and subsequent declining kidney function. Doctor states, rather matter-of-factly, "You have 5-8 years." Really? I say different. Big deal. Science says different. That is, if you bother taking a look below the surface and beyond the AMA so called "standard of care."
Restoring Glutathione as a Therapeutic Strategy in Chronic Kidney Disease
Nephrol Dial Transplant (2004) 19: 1951–1955
DOI: 10.1093/ndt/gfh266

Conclusion:
The reality of oxidative stress, defined as a rupture
between pro-oxidant and anti-oxidant systems, has been established in chronic renal insufficiency patients.

To date, it is considered a major player in uraemia associated morbidity and mortality. Therapeutic
approaches aimed at an upregulation of intracellular thiol concentration , which controls key molecular mechanisms of cell life, have already led to the demonstration of promising beneficial effects in terms of cardiovascular complications and anaemia correction.
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They deserve to be further validated in both
predialysis and dialysis patients.
And... this brings us straight back to the importance of sulfur - "thiol" - gluta "thio"ne... starting to make sense?
Sulforaphane - here we are, if you've been paying attention over the last few weeks... BACK to broccoli sprouts !
A New Weapon Found To Fight The Effects Of Chronic Kidney Disease And Diabetes

"People with Chronic Kidney Disease (CKD) and Diabetes are five times more likely to die from a Cardiovascular (Heart) event than those without these diseases. However, some vegetables may protect and even reverse the damaging effects of CKD and Diabetes on the heart. Broccoli is one of those vegetables." 
The role of melatonin treatment in chronic kidney disease...
Front Biosci (Landmark Ed), 17, 2644-56 2012 Jun 1

Abstract
The pineal hormone melatonin plays a major role in circadian sleep-wake rhythm. Patients with Chronic Kidney Disease (CKD), especially those who are on hemodialysis, frequently suffer from sleep disturbances. In this review an overview is given of the classification of stages of chronic kidney disease, followed by a presentation of the circadian rhythm disorders in renal disease involving sleep disturbances in relation to melatonin deficiency. The therapeutic benefit of melatonin treatment in sleep disorders related to chronic kidney disease including the controlled trials solving this topic, is described. Furthermore, the beneficial effect of melatonin on blood pressure alterations in CKD states and the protection of melatonin in oxidative stress and inflammation in renal disorders are explored. Finally a hypothetic model is described for the relation between circadian rhythm disorders and CKD.
Anti-Inflammatory Effects of Melatonin in Obesity and Hypertension
Curr Hypertens Rep, 20 (5), 45   2018 May 9
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"Melatonin reduces blood pressure and adipose tissue dysfunction by multiple anti-inflammatory/antioxidant actions and provides potent protection against mitochondria-mediated injury in hypertension and obesity. This inexpensive and multitarget molecule has great therapeutic potential against both epidemic diseases."
Other important players
Food Guidance for Kidney Support



Renal Diet Foods List and Eating Plan for Kidney Disease

A Wondrous Roots sample protocol for chronic kidney disease...(but all these things are good for a bazillion "things!")

SAMPLE PROTOCOL CHRONIC KIDNEY DISEASE

WHEN GETTING READY FOR THE DAY:

           COQ10 PLUS PATCH – 1 patch apply to skin as directed mitochondrial energy shown to support kidney health – info provided separately

IN THE MORNING (mix together in about 2-3 oz water/juice and drink):       

           SULFORAPHANE POWDER – ΒΌ tsp to start, work up to 1 tsp daily  source of sulfur for kidney health

           MSM POWDER – 1/8 tsp to start, work up to 1 teaspoon daily source of sulfur -these are all in the glutathione family which is huge for kidney health and more

WHEN CONVENIENT DURING THE DAY: 
           BENFOTIAMINE 300 MG – 1 capsule prevent glycation damage from diabetes which damages nerves and kidneys; hopefully will help with existing neuropathy and prevent further progression

           S-ACETYL-L-GLUTATHIONE 300 MG – 1 capsule glutathione is terribly low in diabetics and in people with kidney disease, also for overall health, cancer prevention, cardiovascular, more, and prostate 

           THORNE BASIC NUTRIENTS 2/DAY – 2 capsules overall health support, trace minerals, etc. Works with the other things.  

WITH SUPPER: 
           BENFOTIAMINE 300 MG – 1 capsule as above
           MELATONIN POWDER – 1 scoop take with a bite of food or put on tongue and chase with water.  High-dose for diabetes, cardiovascular, kidney
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