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Your monthly news & updates
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ECTS Announcements and Events
Reminder: ECTS 2020 abstract submission
deadline
approaching:
13 January 2020
Submit here
your Abstracts & Clinical Cases
- Become an active ECTS member, part of a dynamic community - Join or renew your membership now
- ECTS Webinar: Bone Fragility in CKD. 16 January 2020 4pm CET by Martine Cohen-Solal - Register here
- ECTS is committed to ensuring that our offerings and services meet the needs and expectations of our members: give us crucial insights into your experiences as a member and your needs. Participate in a Membership Survey - Participate Now - deadline: 17 January 2020
- ECTS Named Awards: help us rewarding our distinguished colleagues who have helped to advance the field by making your nomination today - deadline: 27 January 2020
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ECTS Annual congress, 16-19 May 2020, 15 May Pre-congress day, Marseille, France - More information
Other Announcements and Events
- Paget's Awareness Day 2020 -11th January 2020 - More information
- 1st International Meeting on Endocrine-related OsteoPorosis (EOP), Catania, Italy, 13-14 March 2020 - More information
- Inaugural International Sarcopenia Translational Research Conference (ISTRC), Newcastle Upon Tyne, UK, 11-12 June 2020 - More information
- ICCBH Bone School: Educational Course on Paediatric Bone Disorders and Rare Bone Diseases 29 June - 1 July 2020 - More information
- 14th International Conference on Osteogenesis Imperfecta (OI2020) - abstract submission and registration now open, Sheffield, UK, 5-8 September 2020 - More information
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Basic/Translational research programme at the ECTS 2020 congress in Marseille, France.
About to turn the page into a New Year, I am very happy to share with you the exciting outlooks on what will undoubtedly be one of the most marked ECTS activities in 2020: our annual meeting. The 47
th
European Calcified Tissue Society Congress will be held in just a few months in Marseille, the largest historical port city in southern France, located right at the Mediterranean Sea.
The Scientific Programme Committee for the ECTS 2020 meeting has been preparing an attractive and diverse assembly of sessions directed at clinical researchers, basic and translational scientists, and allied health professionals working in the musculoskeletal field.
As the Basic Science Co-chair for the committee, it is my pleasure to announce the part of the programme outline that has been designed to bring an outstanding set of speakers and exciting topics to the basic and translational researchers in our field. One of the key points of attention will be to offer multiple symposia, workshops and interactive sessions focused on the
newest technology developments.
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2020 and the new ECTS Newsletter team
by
Teun de Vries, Editor in Chief
First of all, the ECTS Newsletter team wishes you a wonderful, scientifically and clinically inspiring 2020. As you have read in the December 2019 issue, two esteemed members of the team who were there right from the beginning, have said farewell. Now, from my side, it is a great pleasure to write a great THANK YOU for Carmen Huesa and Marco Ponzetti. First of all, Carmen, thank you for your continuous involvement, and for your articles on topics that matter! Women in science, Career perspective of post-docs are a few I remember. Secondly, Marco, thank you for your contributions, not only on stressed-out PhD students, but, importantly, on composing the newsletter E V E R Y month! That is a great accomplishment that should not be forgotten.
I am happy to announce that we have found two keen and eager new team members who will try to fill the vacuum left by Carmen and Marco. Below, Antonio Maurizi and Petar Milovanovic will introduce themselves. For 2020, the ECTS NL will continue to cover the relevant topics that should be in it: the news around ECTS and its annual congress, new developments within the bone field, new societal aspects that are relevant for a vivid scientific society such as ours, news the world and of course the portraits of the national bone and mineral societies. There are many countries within Europe to be exposed, this year starts off with Germany in this issue. As a newsletter team, we are privileged to be advised by Roberta Mugnai from the ECTS staff as well as from Anna Teti from the Board of the ECTS. We cannot do without them. We hope to provide you, readers, with the news you are interested in and that you would like to read in an ECTS Newsletter. Feel free, of course, to suggest to me, at [email protected] any omission that you would like to be covered.
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20 years "Dachverband Osteologie" 1999 - 2019
by Andreas Kurth, chairman of the DVO and Peyman Hadji, vice chairman of the DVO
The "Dachverband Osteologie" (DVO -
http://www.dv-osteologie.org) is a tri-national umbrella association of currently 21 medical and scientific societies from Austria, Germany and Switzerland. The DVO covers the whole breadth of the field of bone diseases. Over the last 20 years, the DVO has established a concept for quality care regarding diagnostics and treatment for patients with bone disorders. Hereby, the widespread disease of osteoporosis with 6-7 million patients affected in Germany, plays a central role, but other bone disorders as well, such as Paget's disease, bone metastases, primary benign and malignant bone tumors, and rare bone diseases, are addressed.
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New Paget's from ancient bones and Paget's awareness Day 2020
Intro by Petar Milovanovic
In a recent study on medieval skeletons from England (PNAS, 2019), Shaw et al. analyzed the skeletons with atypical and extensive pathological changes morphologically resembling contemporary Paget's disease of bone (PDB) but with some important differences. These differences included extensive disease (75% of bones in some affected skeletons), low age-at-death (most individuals affected were younger than 50 years), and high disease prevalence in the adult sample (16%), but little evidence of bone deformities. Macroscopic and radiographic analysis combined with characteristic pathological changes and molecular signatures supported a retrospective diagnosis of an atypical form of PDB. By paleoproteomic analysis they identified sequestosome 1 (SQSTM1) or p62, a protein central to the pathological milieu of PDB, as one of the few noncollagenous human sequences preserved in skeletal samples, including teeth. A very interesting aspect of the study, is that proteins could be identified, even after many centuries! Targeted proteomic analysis detected >60% of the ancient p62 primary sequence, with Western blotting indicating p62 abnormalities. Direct sequencing of ancient DNA excluded contemporary PDB-associated SQSTM1 mutations. The researchers suggested that the ancient p62 protein is likely modified within its C-terminal ubiquitin-associated domain. This study highlights the new possibilities to diagnose atypical PDB in ancient skeletal populations and contributes to the understanding of the history/evolution of PDB.
We are happy to support Paget's Awareness Day 2020 (11th January 2020). To promote the Awareness Day the Paget's Association has produced a documentary describing the story behind the cited recent research on a form of PDB that affected people in the UK in medieval times. The trailer (available now) and full documentary (to be released on 11th January at 11:00 GMT) can be accessed at
https://paget.org.uk/pagets-awareness-day
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ECTS Announcements and Events
Reminder: ECTS 2020 abstract submission
deadline
approaching:
13 January 2020
Submit here
your Abstracts & Clinical Cases
- Become an active ECTS member, part of a dynamic community - Join or renew your membership now
- ECTS Webinar: Bone Fragility in CKD. 16 January 2020 4pm CET by Martine Cohen-Solal - Register here
- ECTS is committed to ensuring that our offerings and services meet the needs and expectations of our members: give us crucial insights into your experiences as a member and your needs. Participate in a Membership Survey - Participate Now - deadline: 17 January 2020
- ECTS Named Awards: help us rewarding our distinguished colleagues who have helped to advance the field by making your nomination today - deadline: 27 January 2020
-
- ECTS Annual congress, 16-19 May 2020, 15 May Pre-congress day, Marseille, France - More information
Other Announcements and Events
- Paget's Awareness Day 2020 -11th January 2020 - More information
- 1st International Meeting on Endocrine-related OsteoPorosis (EOP), Catania, Italy, 13-14 March 2020 - More information
- Inaugural International Sarcopenia Translational Research Conference (ISTRC), Newcastle Upon Tyne, UK, 11-12 June 2020 - More information
- ICCBH Bone School: Educational Course on Paediatric Bone Disorders and Rare Bone Diseases 29 June - 1 July 2020 - More information
- 14th International Conference on Osteogenesis Imperfecta (OI2020) - abstract submission and registration now open, Sheffield, UK, 5-8 September 2020 - More information
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ECTS is thankful to its Corporate Members and other companies that have supported ECTS activities through unrestricted educational grants. These sponsors have in no way contributed to or influenced the content.
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Editor in chief: Teun De Vries (Amsterdam, The Netherlands)
Co-editors: Petar Milovanovic (Belgrade, Serbia), Cristiana Cipriani (Rome, Italy)
Antonio Maurizi (L'Aquila, Italy)
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