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Stan Gerson, MD
Director, Case Comprehensive Cancer Center
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Answering the NCI's Provocative Questions
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The National Cancer Institute (NCI) has for the past nine years tried to encourage attention to unanswered questions in cancer research. Led by Ed Harlow, now under three NCI directors, a series of nationwide caucuses, including one here at the Case Comprehensive Cancer Center a few years back, have helped to identify the questions of the time.
Now, in its next iteration, are a set of nine new provocative questions (PQs). Please, have a look, as there is a question for each of us to tackle. These R level grants have deadlines of April and November, so now is the time to conceive, think and write. Rather than a diversion, think of ways to link your expertise to one of these key questions. The Cancer Center's program leaders will be glad to look over a specific aims page as soon as you generate it. Below you will find the nine questions and a link to the grant RFA.
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PQ1: What are the underlying causes of the unexplained rising incidence in early-onset cancers?
PQ2: How does intermittent fasting affect cancer incidence, treatment response, or outcome?
PQ3: How do selective pressures affect cell competition and cooperation during cancer initiation and development?
PQ4: What mechanisms explain sex differences in cancer incidence, lesion location, or response to therapy?
PQ5: What strategies can block or reverse the emergence of new cell lineage states induced by cancer treatments?
PQ6: How can cancer cachexia be reversed?
PQ7: What methods can be developed to integrate patient-generated health data into electronic health records?
PQ8: What strategies improve and sustain coordination of comprehensive healthcare for underserved cancer patients with comorbidities? For this question, underserved populations include
NIH-designated health disparity populations.
PQ9: What methods can be developed to effectively study small or rare populations relevant to cancer research?
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Webb Hooper appointed as Deputy Director, National Institute on Minority Health and Health Disparities
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The Case Comprehensive Cancer Center thanks
Monica Webb Hooper, PhD for her leadership and dedication to our mission since joining the Center in 2016.
The Cancer Center is pleased to announce that in March, Dr. Webb Hooper will assume the role of Deputy Director of the National Institute on Minority Health and Health Disparities (NIMHD), one of the 27 NIH institutes.
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This is truly a remarkable opportunity for Dr. Webb Hooper. In this role she will direct the nations’ health research efforts in minority health and help to define actionable interventions to improve the well-being of all underserved across the country. We are deeply appreciative of her impact on all of us here, but recognize the unique opportunity that this represents. We have high expectations that her focus and dedication to this mission will result in transformative national response and will “move the needle” in many hard to manage health issues.
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Trapl named Director, Prevention Research Center for Healthy Neighborhoods
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Effective February 1,
Erika Trapl, PhD is serving as Director of the
Prevention Research Center for Healthy Neighborhoods (PRCHN) at Case Western Reserve University. She succeeds PRCHN Founding Director,
Elaine A. Borawski, PhD, whose vision led the center in addressing chronic health issues faced in disadvantaged Greater Cleveland neighborhoods for the past 10 years. Dr. Trapl is an associate professor in the Department of Population & Quantitative Health Sciences and Co-Leader of the
Case CCC's Cancer Prevention, Control & Population Research Program. Please join us in congratulating her on her new role as she continues to champion the PRCHN mission of fostering partnerships within low-resource neighborhoods to develop, test, and implement effective and sustainable strategies and interventions to prevent and reduce the burden of chronic disease.
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Center for Computational Imaging and Personalized Diagnostics Seeking Full- and Part-Time Researchers
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The Center for Computational Imaging and Personalized Diagnostics (CCIPD) at Case Western Reserve University (CWRU) is seeking talented and motivated researchers across all levels (summer students, undergraduate, graduate, and postdoctoral researchers) with interest and expertise in computer science to work on radiomics, artificial intelligence, and machine learning in the fields of medical imaging, radiology, digital pathology, oncology, cardiovascular disease, nephrology and ophthalmology.
Interested candidates should have a background in programming, ideally with both MATLAB and C++. Undergraduate and graduate students will be working on development of image analytic/machine learning algorithms for clinical applications.
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Join Team Case CCC in VeloSano 2020!
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The Case Comprehensive Cancer Center (Case CCC) is honored to make its sixth appearance in
VeloSano, a year-round fundraising initiative and "Bike to Cure" weekend to support lifesaving cancer research. Our continuing goal is to bring sustainable funding to cancer research by enlisting the passion and energy of thousands of people who wish to give back... including
YOU! We raised nearly $94,000 in 2019 and every dollar goes directly toward cancer research. In our six years of participation, more than $1,000,000 of VeloSano fundraising totals have come back to the Case CCC to award researchers as pilot funding for cancer research projects.
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The Case CCC will provide complimentary registration fees and jerseys again this year. Contact team captains
Caroline El Sanadi or
Mary Wright for the registration fee waiver code to sign up! While registration is complimentary, all riders are responsible for meeting the minimum fundraising commitment associated with the
distance they ride. Fundraising can begin as soon as you register to ride and continues through October 1, 2020.
Registration is open now and information about volunteering for our cheer station and supporting our team through sponsorship will be available soon!
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Mon, Feb 10
Shared Resources Directors Meeting
12p WRB 1-422D
Case CCC Junior Faculty Meeting
"IP & Technology Transfer"
1:30p WRB 1-422D
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Weds, Feb 12
Breast Cancer Update
11:45a Embassy Suites Independence
Disparities SPORE Meeting
Natalie Joseph, MD and Fred Schumacher, PhD
5-7p WRB 2-136
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Thurs, Feb 13
D
evelopmental Therapeutics Journal Club
9a NE6-218
Immuno-Oncology Seminar Series
Tyler Curiel, MD, MPH
11a NC1-202
Synthego CRISPR Seminar
11:30a WRB 2-136
Immunology Journal Club
12p WRB 5-136
Molecular Biology and Microbiology Seminar
1p SOM W203
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Fri, Feb 14
Taussig Cancer Institute Grand Rounds
8a CA5-120
UH Seidman Cancer Center Grand Rounds
8a Wearn 137
Cancer Center Seminar Series
Jan Grimm, PhD
12p WRB Auditorium
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Mon, Feb 17
Wolstein Research Building Faculty Meetings with Stan Gerson
3:30p WRB
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Tues, Feb 18
Cancer Drug Discovery and Resistance
3p WRB 1-422D
Pavey Family Designated Professorship Ceremony
Mark Griswold, PhD
4:30p WRB
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Weds, Feb 19
Biomedical Innovation and Entrepreneur Club
4-6p BRB 932
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Thurs, Feb 20
D
evelopmental Therapeutics Journal Club
9a NE6-218
Molecular Biology and Microbiology Seminar
1p SOM W203
Reception Celebrating Monica Webb Hooper, PhD
4-6p WRB Lobby
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Fri, Feb 21
Taussig Cancer Institute Grand Rounds
8a CA5-120
Cancer Center Seminar Series
David Chambers, DPhil
12p WRB Auditorium
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Cancer Center Seminar Series
February 7, 12p
WRB Auditorium
Our weekly seminar series features
Quintin Pan, PhD at noon today in the auditorium of the Wolstein Research Building.
Dr. Pan is Deputy Director for Research and the Dr. Lester E. Coleman, Jr. chair in Cancer Research and Therapeutics at University Hospitals Seidman Cancer Center. He is also a professor of otolaryngology at the Case Western Reserve University School of Medicine and Co-Leader of the Case CCC's Molecular Oncology Program. In addition to his administrative roles, he maintains a vibrant research program on novel target discovery and drug development in head and neck cancer.
He will present, "Novel Biomarker and Drug Discovery Platforms for HPV+ Head and Neck Cancer" on behalf of the Molecular Oncology Program.
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Cancer Center Seminar Series
February 14, 12p
WRB Auditorium
Next week's cancer center seminar will be presented by
Jan Grimm, MD, PhD on behalf of the Cancer Imaging Program.
Dr. Grimm is Associate Attending at Memorial Hospital, Associate Professor, Cornell Radiology and Gerstner Graduate School of Biomedical Sciences, and Associate Member of the Molecular Pharmacology Program at Memorial Sloan Kettering Cancer Center.
He will present, "Imaging with the Speed of Sound and Light" at noon in the WRB Auditorium.
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Bring the Power of CRISPR to Your Research
February 13, 11:30a-1p
WRB 2-136
Join Synthego to learn more about the easiest way to start using CRISPR in your research. See how your lab can use genome engineering to drive your research forward and accelerate discoveries.
Register for this seminar to learn how you can best utilize Engineered Cells and CRISPRevolution Kits in your research with new, affordable, and guaranteed solutions from Synthego. Join the Synthego team to learn about:
- How to design, edit, and analyze your CRISPR experiment
- Easy solutions to generate cell lines
- Fastest path to use CRISPR in your research
Space is limited. Lunch will be provided.
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Pavey Family Designated Professorship Ceremony
February 18, 4:30p
Wolstein Research Building
Join President Barbara R. Snyder to celebrate the generosity of the Pavey Family and the appointment of
Mark Griswold, PhD as the Pavey Family Designated Professor of Innovative Imaging - Revolutionizing the Worlds of Education and Medicine.
A ceremony will take place on Tuesday, February 18 at 4:30 pm in the Iris S. and Bert L. Wolstein Research Building with a reception to follow. Dress is business attire and complimentary valet parking will be available off of Circle Drive.
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4 Weeks Away: 4th Annual Cancer Disparities Symposium
March 6, 2020
Tinkham Veale University Center, CWRU
The
4th Annual Cancer Disparities Symposium
: Cultivating Science and Community Engagement to Address Cancer Health Disparities is less than one month away! Don't miss the opportunity to join researchers, physicians, and community leaders as we share cutting edge science and innovations in community engagement.
The
symposium agenda is now posted and features sessions on Cancer Disparities and Underserved Populations, such as sexual and gender minorities, Amish, and muslim women, Community Engagement and Support Programs, and Cancer Disparities Research and Community Engagement, plus invited presentations selected from standout abstract submissions. The final session of the day will be a multidisciplinary and thought-provoking panel discussion that will crystallize the energy and inspire us to continue toward the ultimate goal of health equity.
Robert T. Croyle, PhD of the National Cancer Institute will deliver the day's Plenary Address and and
Lucio Miele, MD, PhD from Louisiana State University is this year's Distinguished Scientific Keynote speaker.
Attendees are eligible to receive six (6) continuing research education credits (CRECs) or six (6) continuing education contact hours (CECH) units of advanced level training in health education. Meals, materials, refreshments and parking will be provided.
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Research ShowCASE 2020
April 17, 9a-3p
Veale Convocation Center
CWRU faculty, staff and students by presenting your work at
Research ShowCASE 2020. The event will provide an opportunity for CWRU researchers to display your research in a traditional scientific poster or other creative means. We encourage University Hospitals, Cleveland Clinic, MetroHealth Medical Center and the Louis Stokes Cleveland VA Medical Center researchers to participate.
In addition to the opportunity to display and share your work, undergraduate and graduate students, professional students and postdoctoral scholars are encouraged to participate in the research competition, which will include having your presentation evaluated and feedback provided. Cash prizes will be awarded to winning entries.
In order to display your work at
Research ShowCASE, you will need to submit an online abstract describing your research. If you are a student or post-doc, your faculty adviser will need to approve your submission.
Abstract Deadlines:
Graduate and professional students, post-docs, faculty, staff and affiliates: February 16, 2020
Undergraduate and high school students: March 20, 2020
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Save The Date: Cancer Stem Cell Conference 2020
August 4-6, 2020
Tinkham Veale University Center
The Case Comprehensive Cancer Center and the National Center for Regenerative Medicine invite you to save the date for CSC 2020!
Now in its fourth year, CSC 2020 will feature renowned thought leaders in the field of cancer stem cell research. This conference is guaranteed to offer cutting-edge keynote presentations from a variety of niches within the field. Join world-class investigators for this three-day summit and network with scientists and clinicians advancing cancer stem cell research and therapeutic applications.
Registration will open in February.
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Save The Date: Great Lakes Breast Cancer Symposium 2020
October 4-6, 2020
Tinkham Veale University Center, CWRU
As host site for the 2020 Great Lakes Breast Cancer Symposium, the Case Comprehensive Cancer Center encourages you to mark your calendar for the symposium taking place October 4-6, 2020.
The symposium highlights ongoing basic, translational, clinical and population studies addressing the biological mechanisms, management and prevention of breast cancer. Researchers from participating institutions will share their exciting work with a goal to develop cross-institutional collaborations.
This year's event features two keynote speakers:
- Carlos Arteaga, MD, Director of the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center
- Helen Piwnica-Worms, PhD, Professor of Experimental Radiation Oncology at the University of Texas MD Anderson Cancer Center
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Additional Upcoming Events
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Breast Cancer Update: Review of Breast Cancer Symposia
February 12, 2020 11:45a-4:15p
Embassy Suites, Independence
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This review course will summarize highlights from the national breast cancer meetings, with a focus on the clinical implications of the new information presented at these meetings. Medical oncologists, breast surgeons, radiation oncologists, women’s health, nurses, nurse practitioners, physician assistants, residents and fellows and other health care providers with an interest in the management of patients with breast cancer should attend this course.
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2020 Multidisciplinary Head and Neck Cancer Update
February 14-15, 2020
Fort Lauderdale, FL
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This course will provide practicing physicians, residents, fellows, and nurses in medical oncology, otolaryngology, radiation oncology, and head and neck surgery with a contemporary update of management strategies of head and neck cancer using a multidisciplinary approach. Lecture and panels will provide a forum for discussion of updated therapies and new treatment innovations.
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Management of Checkpoint Inhibitor-Related Toxicity Conference
March 6, 2020
InterContinental, Cleveland
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Immune checkpoint blockade leads to a new spectrum of dysimmune toxicity requiring collaboration between oncologists, providers, and specialists to improve the understanding of the mechanism, diagnosis, and management of immune-related adverse events (irAEs). The goal of this conference is to bring together a multidisciplinary group of clinicians to share expertise and improve the care of patients receiving immune checkpoint inhibitor therapies.
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NCCN 2020 Annual Conference
March 20-22, 2020
Orlando, FL
The National Comprehensive Cancer Network (NCCN) 2020 Annual Conference agenda includes 30 educational sessions featuring the latest advances in oncology care, including interactive patient case studies. Session topics include: HPV-Associated Cancers, Patient-Reported Outcomes, Clinical Trial Implementation, Value-Based Payment Models, Role of Biosimilars and more.
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AACR Annual Meeting
April 24-29, 2020
San Diego Convention Center
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The American Association for Cancer Research (AACR) Annual Meeting program covers the latest discoveries across the spectrum of cancer research—from population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy—and highlights the work of the best minds in research and medicine from institutions all over the world.
This year's meeting will take place April 24-29, 2020 at the San Diego Convention Center in San Diego, CA.
Final data for clinical abstract placeholders is due Thursday, February 20.
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2020 NIMHD Health Disparities Research Institute
August 3-7, 2020
NIH Campus, Bethesda, MD
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The National Institute on Minority Health and Health Disparities (NIMHD) will host the Health Disparities Research Institute (HDRI) from August 3-7, 2020 at the NIH campus (Natcher, Building 45 conference center rooms). The HDRI aims to support the research career development of promising early-career minority health and health disparities research scientists and stimulate research in disciplines supported by health disparities science. Applications will only be accepted from extramural scientists who meet NIH’s
Early Stage Investigator (ESI) eligibility criteria.
The program will feature lectures, mock grant reviews, seminars, and small group discussions on research relevant to minority health and health disparities. It will also include sessions with NIH scientific staff engaged in related health disparities research across the various institutes and centers.
Extramural scientists, early in their careers with research foci in minority health and health disparities, are encouraged to apply to the institute.
Applications are now open and must be submitted via the HDRI application portal by
Monday, March 9, 2020 at 5pm EST; emailed applications will not be accepted. Applicants are encouraged to apply before the deadline since late submissions will not be accepted. Questions may be directed to
HDRI@nih.gov.
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Deadline: March 31, 2020
The Case Comprehensive Cancer Center is accepting applications for the following opportunities through Tuesday, March 31, 2020. View each RFA below for more information.
- Up to 3 $120,000 awards to be distributed
- Requires teams of 2 Case CCC faculty members, both listed as PI
- Up to 2 $75,000 awards to be distributed
- Open to all junior or independent faculty and Associate Case CCC members
- 1 project, up to $120,000 to be awarded
- Requires teams of 3 or more senior Case CCC members
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Oncology Times - Feb 5, 2020
"As a leader, using your authority to support not just the favored group but also others may be an opportunity to display wisdom as well as real empathy," writes
Brian Bolwell, MD, Chairman of the Cleveland Clinic Taussig Cancer Institute and Deputy Director for Cleveland Clinic at the
Case Comprehensive Cancer Center.
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Weekly NIH Funding Opportunities and Notices
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Notices
Funding Opportunities
AIDS Application Due Dates: July 28, 2020; July 28, 2021; July 28, 2022
AIDS Application Due Dates: July 28, 2020; July 28, 2021; July 28, 2022
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Use the button below to submit all your news, events, announcements and communications requests to the Case CCC Marketing and Communications team!
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