Your clinical data is compelling and the prospect of launching your first product is becoming quite real. You may have more questions than answers.
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BioPharmGuy
Posted a task on Upwork to automate a one-off data extraction task. Someone responded that it sounded straightforward and they would be able to do it. Followed up to clarify whether this person could automate it - doing it manually would take 40 hours. They said no, but if we would teach them how to do it, they would be willing to learn. (Head explode emoji)
If you're new around here you may not know we have a list of bioscience organizations around the world. If you know of any we're missing, please let us know - we would be happy to add them if they're biotech-focused.
Also, if you know anyone looking for an entry-level job, we add 30-70 new jobs to our entry-level jobs list per week. Let the new college grads in your life know.
Addition & Attrition
11 companies added, four removed. Summary available on downloads page.
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SafeRx Pharmaceuticals
In a time when everyone is researching non-opioid painkillers, SafeRx is taking another route. They're looking to formulate a combination product which will integrate an opioid with an alcohol-deterrent molecule. They claim 22% of opioid overdoses occur alongside alcohol consumption and they believe this product will help address the matter. They're launching a crowdfunding round.
Not a great sign when you're entering a therapeutic field that is such a scary prospect no institutional investors will touch it. We wish them luck, but if opioids have taught us anything throughout history, it's that people are gonna find a way to abuse them. This is a real longshot.
Amgen
The company's product Lumakras was approved by the FDA for certain types of non-small cell lung cancer. The product's target is a KRAS G12C mutation that was previously considered "undruggable" due to its lack of available binding sites.
This approval was for patients with non-small cell lung cancer that have that KRAS G12C mutation and who have had one prior systemic therapy. This specific KRAS mutation is found in about 40% of KRAS-driven NSCLC cases, which is something like 12,000 people per year. Great news for them and their families. Undruggable targets around the world are on notice. Big biotech's comin' for ya, brother...
If it works, it works
Akili Interactive has an FDA-approved, prescription video game for treatment of ADHD. That's probably the most unlikely treatment for ADHD you could have imagined. Akili just raked in another $110M in funding this week, so maybe this time they'll come up with a prescription french fry for people with high cholesterol.
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Featured Academic Program: UNT Health Science Center
If you're interested in advancing your career in Drug Discovery & Development, UNT Health Science Center at Fort Worth has a remote program available through their College of Pharmacy. They're offering an online Certificate program (four courses, two to four semesters) as well as a more traditional master’s degree (11 courses, one to three years) which is 80% remote, 20% in-person capstone project/industry internship in Fort Worth.
Certificate is less than $4400 while the master’s is $10k in-state tuition. It's not uncommon to get a $10k raise switching to your first job after getting a master’s, so you could see a quick payback on the investment.
If you're looking to move your career forward, check them out.
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Salmonella Vaccine
With the strides made against Covid, other vaccines are starting to get a lot more interest. There are the usual suspects like flu, malaria & HIV. But a more intriguing idea is vaccination against salmonella.
Food poisoning is WAY more common than most people realize - there are an estimated 48 million cases per year in the US. That makes sense - we collectively eat about 350 billion meals annually in America, not including 4th meals.
There are a bunch of bacteria and viruses that cause food poisoning, but knocking out one can't hurt. Chicken sashimi anyone?
Free Cicadas
Lot of talk about cicadas, but we haven't heard a single peep from one up here in West Lafayette yet. Newsy outlets are grasping for clicks by publishing articles about cicada recipes as if anyone is really going to eat them. People don't like free stuff that much do they?
Well, yes they do, as Krispy Kreme has shown by giving away 1.5 million free donuts to vaccinated Americans. Is one free donut not enough for your cheap self? Then tomorrow is your lucky day - everyone gets two...TWO free Krispy Kreme donuts. (ah ah ah ah)
By the way, CVS is running a vaccine sweepstakes for those who were vaccinated at a CVS or at a CV-run clinic. One of the prizes is a one week norovirus safari, otherwise known as a cruise. Defeat one virus, face another - it's like a real world video game.
Back to the cicadas - if you decide to partake, the FDA would like you to know that shellfish and cicadas are related and if you're allergic to shrimp or lobster you should avoid eating the bugs. What a bummer.
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ETC.
Imposter Nugget
Kids around the world are all-in on Among Us, but it seems there are more than a few Richie Rich wannabes out there. Bidding on eBay for an Among Us-shaped chicken nugget from McDonald's is going through the roof - almost $100,000 this morning, though some of those bids are definitely "sus". Bidding ends at 3:00 am eastern - Don't wait!
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