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Your monthly news & updates
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ECTS Announcements and Events
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Thank you for contributing to the success of the ECTS 2019 congress in Budapest! Check out the congress photo gallery
here
- ECTS Webinar: Bone-muscle cross-talk under pathological conditions. 27th of June 2019 4 pm CET by Maria Luisa Bianchi, 27 June 2019 4 pm CEST - Register here
- AMGEN competitive grant program in bone research to improve outcomes of osteoporotic patients. Deadline: 28 June 2019 (11:59 pm PT) Details here
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ECTS PhD Training Course 2019, 8-10 September 2019, Bologna, Italy -
More information
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ECTS-Mellanby-SVGO Training Course on Diagnostic Tests for Osteoporosis "Bone Turnover Markers",
12 September 2019, Basel, Switzerland -
More information
Other Announcements and Events
- Free Webinar: Connective Tissue-Specific Stem and Progenitor Cells: from Biology to the Clinic, Challenges and Advances. June 18, 2019 12pm ET- Register here
- Bisphosphonates' 50th anniversary meeting, Sheffield, UK 15-17 July 2019 - More information
- The 5th International meeting on Bone Marrow Adiposity, SDU, Odense, Denmark, 21-23 August 2019, Early bird and Abstract Submission Deadline 15 June 2019. More information
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ECTS 2019: Another success
By Roberta Mugnai and Anna Teti
Thanks to the effort of the organisers, the scientific programme committee, the ECTS Board members and the delegates, the ECTS 2019 congress held in Budapest, Hungary, 10-14 May 2019, turned out to be another very successful event: over 1170 registrations, more then 250 delegates attending the pre-congress day, over 60 oral presentations, 11 working groups, joint sessions with ICCBH, ASBMR, IFMRS, KSO, KSBMR, JSBMR and CSBMR, 3 educational symposia, 3 industry symposia, 10 meet the expert sessions and a rich ECTS Academy programme including Next Generation Synergy, New Investigator (NI) mentorship, NI seminar, Poster Forum and Charity event. Last but not least, 5 excellence awards, 2 fellowships, over 40 awards based on abstract score, and 10 clinical scholarship grants were presented at ECTS 2019. We wish to thank all delegates, sponsors, supporters and exhibitors who contributed to make this dream come true.
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ECTS Academy experience during Budapest 2019
By Annegreet Veldhuis-Vlug
During the annual meeting of the ECTS, the ECTS Academy organises special events for new investigators and this year in Budapest, these attracted a lot of attention!
We started of with the 'Next Generation Synergy' session on Friday afternoon to introduce an array of European and Eastern young investigator societies. Representatives from the MuSKitYr (Germany), BRS (UK), EMEUNET (EULAR rheumatology), KSBMR and KOS (South-Korea), CSOBMR (China) and JBMRS (Japan) explained how young investigators from their respective countries organise themselves and work together to promote their research and clinical activities and hearing about each others societies inspired new ideas and initiatives. Certainly this will lead to new future collaborations! The session ended with an update on the most interesting articles published by members of the Academy both in basic science presented by Abbas Jafari and in clinical science presented by Daniela Merlotti. This overview nicely showed the outstanding research during the last year (and sometimes even multiple years!) by our academy members.
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In fulfillment of the ECTS mission to foster excellence in bone and musculoskeletal research, during the 2019 Congress in Budapest several major prizes were awarded: the Steven Boonen Clinical Research Award, Mike Horton Basic/Translational Award, Iain T Boyle Award, Philippe Bordier Clinical Award, ECTS Excellence in Research Award. If you want to know who the awardees were, and why they won these prestigious prizes, click on the "read more" link below.
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The resting zone stem cells
By Marco Ponzetti.
The idea that cartilage, including the growth plate, contains pluripotent stem cells and oligopotent progenitors has been around for several years now. However, thanks to new lineage tracing methods and talented investigators who have been using them in a clever way, this has been now proposed. Two recent papers, which were published almost synchronously on Nature (Links below) by Noriaki Ono's and Andrei Chagin's groups, propose that the resting zone of the growth plate contains a population of parathyroid hormone related peptide-positive self-renewing cells (according to Ono's group), each of which gives rise to a single column of chondrocytes. These eventually undergo hypertrophy and are thought to become active osteoblasts (or bone marrow reticular stromal cells), allowing bone elongation. In fact, postnatal ablation of these cells was able to disrupt growth plate morphology, tightening the proliferating zone and inducing premature chondrocyte hypertrophy, which could result in deformities and impaired growth. The group of Andrei Chagin, who held a very nice talk at the ECTS 2019 congress in Budapest, took the concept a step further, going deeply into the clonal dynamics of the resting zone stem cells. They proved that during the early phases of development (foetal and neonatal), chondroprogenitors are gradually depleted during bone growth, and lack typical features of stem cells. However, with the formation of the secondary ossification center, the resting zone stem cell arises from non-stem progenitors (one of very few examples in the whole organism), following activation of the mTORC1 pathway. These two reports brought to light this novel and peculiar stem cell, which was hiding undetected in all of our growth plates...until now.
Enjoy the reading!
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ECTS Announcements and Events
-
Thank you for contributing to the success of the ECTS 2019 congress in Budapest! Check out the congress photo gallery
here
- ECTS Webinar: Bone-muscle cross-talk under pathological conditions. 27th of June 2019 4 pm CET by Maria Luisa Bianchi, 27 June 2019 4 pm CEST - Register here
- AMGEN competitive grant program in bone research to improve outcomes of osteoporotic patients. Deadline: 28 June 2019 (11:59 pm PT) Details here
-
ECTS PhD Training Course 2019, 8-10 September 2019, Bologna, Italy -
More information
-
ECTS-Mellanby-SVGO Training Course on Diagnostic Tests for Osteoporosis "Bone Turnover Markers",
12 September 2019, Basel, Switzerland -
More information
Other Announcements and Events
- Free Webinar: Connective Tissue-Specific Stem and Progenitor Cells: from Biology to the Clinic, Challenges and Advances. June 18, 2019 12pm ET- Register here
- Bisphosphonates' 50th anniversary meeting, Sheffield, UK 15-17 July 2019 - More information
- The 5th International meeting on Bone Marrow Adiposity, SDU, Odense, Denmark, 21-23 August 2019, Early bird and Abstract Submission Deadline 15 June 2019. More information
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ECTS is thankful to its Corporate Members and other companies that have supported ECTS activities through unrestricted educational grants. These sponsors have in no way contributed to or influenced the content.
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Editor in chief: Teun De Vries (Amsterdam, The Netherlands)
Co-editors: Carmen Huesa (Edinburgh, UK), Cristiana Cipriani (Rome, Italy)
Marco Ponzetti (L'Aquila, Italy)
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