The bottleneck that is the purification of oligos, peptides, mAbs and other therapeutics has been removed with YMC’s Contichrom continuous chromatography platform. Both bench jockeys and production people now have a proven means to significantly reduce time to market, resin cost and solvent / buffer consumption. Multiple GMP production sites have already employed YMC’s Contichrom systems to save million$ and accelerate product while reducing space – time for you to look into what multi-column technology can do for you.
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BioPharmGuy
Good news - if you're reading this you survived St. Patrick's Day. Well done. Bye bye winter, hello allergies.
Just realized we list about 10 companies working on Nitric Oxide therapies. It's an important chemical for vascular health and is common in the human body, but at the same time, you can't patent a chemical containing two atoms. It's worth doing basic research on the subject for public health purposes, but as a commercial enterprise it seems unrealistic. #notmymoney
Addition & Attrition
15 companies added, 44 removed this week. Cleared out a bunch of companies whose websites have been down forever. Summary on the downloads page.
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Moderna
They've begun testing a version of their vaccine in children 6 months to 12 years. (They had already begun a trial for 12-18 year-olds). All children will be monitored for a year. Interestingly, adult trial participants are being followed for two years. Not clear why there's such a difference.
FDA has a much higher bar for anything to do with children, so unless the virus starts running wild and affecting children significantly, do not expect a fast emergency authorization for the little ones - probably be another masked up school year in the fall.
Harmony Biosciences
This company was certified as a "Great Place to Work" for the third straight year. Wow, how improbable that a company who paid someone to survey their own employees ended up getting the result they wanted. Amazing!
Think Again
Hey hey, we found some more self-described "thought leaders" here. True visionaries, no doubt.
NovAccess
Initially this looked like any old crappy penny stock, but when we clicked on 'Science & Technology' we were treated with this amazing statement:
"Our Cutting-Edge Approach: Utilization of blockchain-powered AI to collect and analyze data mined through state-of-the-art bio-sensing technologies"
Wow, talk about an opportunistic, jargon-filled piece of nothing. Blockchain is a secure way of recording information - why in the world would you use blockchain to discover drugs? Easy - you wouldn't. Such an inane buzzword statement smacks of desperation.
Team Roast
Scroll down and you will see NuTech told their employees to submit a picture of themselves with their loved ones. Let's go ahead and assume the one guy didn't get the memo.
By the way, their website states that they sell something and they ship it and have a quality policy, but they never explain what they sell. You can see some product names, but no accompanying information. They also mention having "resources available to answer your questions about any of our products", but no links to said resources. What is this, some kind of spinal surgeon speakeasy?
Novaremed
This group is targeting an indication called "painful diabetic neuropathic pain". As opposed to a painless diabetic neuropathic pain?
Lia Diagnostics
Screenwriters may soon have to rely on some other plot device to allow characters to discover secret pregnancies - Lia Diagnostics is now offering flushable pregnancy tests. At $7 each, they're pricier than the sticks, but given time maybe they'll come to be the new standard.
Per their FAQ, simply pee on the pad and get results. They suggest you may flush it, compost it or scrapbook it. First option sounds best, but hey, you do you.
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Eat Your Greens
Can you believe that eating leafy greens is better for you than eating sugar? Shocking that the quality of your plant-based diet is important when determining if it will improve your health. Some amazing insight there. Moral: Plant-based is not a synonym for healthy.
Listen to Your Heart
Researchers out of the University of Washington have used a smart speaker to monitor heart rate, contact-free. They were able to do so by turning the speakers into a short-range active sonar system. "Alexa, am I having a panic attack?"
Lose Weight
But this. This is a tube connecting your stomach to the outside world, aka a stomach-emptying port. It does seem to be a medical improvement on the classic stomach-emptying port known as the esophagus, but since the patient's eating habits aren't really changing, it's more like a highly-invasive, temporary treatment than a solution.
Drug companies are also working feverishly on all manner of pills for weight loss. It's partially plausible to picture popping a pill in perpetuity. Straining a stomach stoma ceaselessly sorta seems psychotic.
Taking pills and draining stomachs - none of it is ideal, but let's face it, for many it is simply too difficult to lose weight and keep it off. Finding answers to this problem could improve a tremendous number of peoples' lives dramatically, and will make others rich in the process. Thus the search will continue.
Take Your Medicine
We warned a while back about the attribution of every ailment under the sun to vaccines. People get sick all the time, so of course some are going to get sick soon after getting a vaccine. That does not mean they got sick because of the vaccine.
On Twitter, Colin the Warrior Monkey did us a service by going through 63 pages of self-reported side effects from the AstraZeneca vaccine and compiled his list of favorites. Highlights are the four people who tried to pin their genital herpes on the vaccine and five others who were bitten or stung by bugs and somehow attributed that to getting a vaccine.
Moral #2: People are crazy.
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