Control Harvesting, Enter for a T-shirt, and Our Latest News
Introducing: Watershed™
A HUMIDITY CONTROLLED WORKSTATION FOR CRYSTALLOGRAPHY
Crystals being harvested from a 96-well plate using the Watershed™ Flex Directed Nozzle
Comparison of two drops after 10 minutes of being opened to air
Simply Prevent Drops from Drying Out
  • Harvest carefully without skins forming
  • Avoid losing crystals to precipitation & degradation
  • Reduce dehydration and crystal non-isomorphism
  • Controllably dehydrate crystals to improve diffraction
If you have ever tried harvesting protein crystals, you know how challenging it can be to mount crystals before the drop starts to dry out. Exposed drops quickly develop skins, precipitate out, or have the crystals deteriorate right before your eyes. You can now easily avoid these undesired outcomes, that can frustrate researchers and reduce the quality of diffraction data. Don't let hard work setting up all of those plates to get crystals go to waste.

Take control of every aspect of crystal harvesting. Avoid dehydration, increase drop working time, prevent degradation, and harvest more crystals from each drop by using the Watershed™ System. The system utilizes a controlled stream of humidified air that helps protect samples from unwanted evaporation and allows users full control of their harvesting parameters.
Humidity Controlled Harvesting Chamber
Direct Nozzle Workstation
Watershed™ was developed in collaboration with Prof. Douglas Juers (Whitman College).

Reference:
[1] “ Improved reproducibility of unit-cell parameters in macromolecular cryocrystallography by limiting dehydration during crystal mounting ,” Christopher Farley, Geoffry Burks, Thomas Siegert and Douglas H. Juers, Acta Cryst. D70, 2111-2124 (2014).
Free T-shirts?
Come see what's new at the ACA Meeting in Toronto!
We will be giving away a limited number of special ACA 2018 MiTeGen T-shirts during the exhibition. Stop by our booth early to make certain to claim yours!
New Additions: Pucks
You asked for it, we delivered. We are now offering a multi-color option for our Universal (Uni-puck) & Cryo-EM Puck systems.
The CombiPuck™ system enables crystallographers to send crystals stored in SPINE standard  magnetic cryovials  to facilities that require  Uni-pucks for automated sample handling .
We are now a convenient location to obtain the p ucks and related tools for use with Rigaku’s ACTOR sample handling system .
In The News:
Illustration: California NanoSystems Institute at UCLA
" CLA researchers have produced the clearest 3-D images to date of the virus that causes cold sores, herpes simplex virus type 1, or HSV-1. The images enabled them to map the virus’ structure and offered new insights into how HSV-1 works. " ... " The scientists used cryo electron microscopy, or cryoEM, to obtain the first atomic model of the virus particle, which is made up of more than 3,000 protein molecules comprising tens of millions of atoms" - UCLA
Photograph: Rosalind Franklin
Credit: Jewish Chronicle Archive/Heritage-Images
Rosalind Franklin was an English chemist and X-ray crystallographer, who is best know for her work on X-ray diffraction images of DNA in the 1950s. Her work also contributed to understanding the molecular structures of RNA, viruses, coal, and graphite. Her pioneering work on DNA led to dramatic discoveries that are still impacting research today. She unfortunately passed away at the age of 37. This month, we recognize her for the incredible work done in a challenging time for female researchers.
Video: Improve Harvesting
Learn about the impact that loop choice has on crystal cryocooling and diffraction quality
Social Media:
Follow us on Social Media to get real-time updates on news in #crystallography and #cryoEM
Follow MiTeGen on social media!
Twitter ‌ Facebook ‌ LinkedIn ‌ Google+ ‌
MiTeGen |+1-607-266-8877 |info@mitegen.com