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At the close of this extraordinary year, we reflect with gratitude on the generous support we have received to continue our urgent work.

Even in this difficult environment, you are enabling us to expand our research initiatives and introduce new programs to assist patients and families. We will continue to push forward aggressively until we find a cure.

There is still time to join with us in 2020 by making your tax-deductible donation.
Gastric Cancer Registry Prepares to Launch Innovative Data Portal
The Gastric Cancer Registry is the first comprehensive repository of clinical and genomic data pertaining to stomach cancer. Its chief aims are to enhance understanding of gastric cancer and to serve as a resource for developing novel prevention, early detection, and treatment strategies. Created in 2011 through a collaboration between the Gastric Cancer Foundation and investigators at the Stanford University School of Medicine, the Registry has grown into a rich resource for biomedical research. The Registry has benefited from the expertise of researchers in cancer biology, molecular technology, genomics, and bioinformatics.

For the past few years, the Registry team has collected archival sample of gastric tumor tissue and associated clinical records. With next generation sequencing and deep computational analysis, the Registry has generated valuable datasets on the unique mutations, microbiome, and immune cell populations in the gastric tumor microenvironment. The principal investigator, Dr. Hanlee Ji, has pledged to make these data available to the scientific community with the aim of catalyzing revolutionary gastric cancer research.
Dr. Hanlee Ji
"The Genome Explorer is a powerful platform for researchers to investigate the molecular complexities of gastric cancer."

-Dr. Hanlee Ji
Hearty Mushrooms for Health

Foundation board member and "Chef without a Stomach," Hans Rueffert, Foundation Board Member and "Chef without a Stomach," Hans Rueffert, shares another one-pot-wonder that is nutrient rich and hearty.

Have you tried one of Hans's recipes? Share it with us! Find more episodes at the Gesundheit Kitchen on gastriccancer.org.
Research Roundup
Despite the challenges raised by the pandemic, researchers continued to make progress in their efforts to combat gastric cancer in 2020. Here are some recent accomplishments:

Five Prime Therapeutics’ FGFR2b-targeted drug combined with chemotherapy improved survival in a phase 2 trial in front-line gastric and gastroesophageal junction cancer. The company is discussing next steps with global drug regulators.

British researchers discovered that a blood test could identify gastric cancer patients who might respond well to EGFR-inhibiting drugs. The study, published in the journal Gut, suggested that some patients could benefit from a single EGFR-targeted drug, avoiding the side effects of harsh chemotherapy. 

Researchers in Taiwan identified two biomarkers that contribute to the growth and spread of gastric cancer and suggested that a blood cancer drug that’s already on the market, midostaurin, could be used to treat patients with high levels of the proteins. They made the discovery using big data to study 30,000 genes from 300 gastric cancer patients.
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