Ready, Set,
May 29, 2019 | 2.0
Dear Colleagues,

We are very excited about our first research retreat taking place this Thursday, May 30th from 2:00 PM to 8:00 PM in the Hale 3rd floor conference room. This will be an opportunity for our scientists and physicians to mingle and explore the groundbreaking and interesting research taking place within our Department. Food, drinks, posters, along with short presentations should make for a fun afternoon and evening. Even if you can’t make the entire event, I encourage you to stop by and catch some of the action.

This month was also extraordinarily successful with a number of awards– see below. Congratulations to the investigators for their hard work and dedication getting these prestigious foundation awards. Some were re-submissions, showing that perseverance pays off.

We are also planning grand rounds with a focus on research education and training, starting in July. Topics will include database research, study design, promotion, IRB, and navigating an academic career. More info to follow in the next newsletter.

Best

Danny
Awards & Grants
Mieke Soens - Foundation of Anesthesia Education and Research (FAER) mentored research training grant (MRTG) for her work entitled “ The Role of Specialized Pro-resolving Mediators in the Development of Persistent Post-Surgical Pain. ” Her mentoring team is comprised of Drs. Serhan (primary) and Rathmell and Schreiber.
Vesela Kovacheva - Foundation of Anesthesia Education and Research (FAER) mentored research training grant (MRTG) for her work entitled “Genome Wide Association Study of Patients with History of Postpartum Hemorrhage." Her mentors are Richa Saxena, PhD, Brian Bateman, MD, MSc, and Kathryn Gray, MD, PhD.
Naida Cole - 2019 BWH Faculty Career Development Award for her project entitled “ Second-line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial. ”
Sara Seifert - 2019 Society of Obstetric Anesthesia and Perinatology (SOAP) Young Investigator Grant for her project entitled “ Tranexamic Acid Administered After Delivery: Maternal Pharmacokinetics, Pharmacodynamics, and Coagulation Status. ” Her mentorship team consists of Drs. Michaela Farber, Brian Bateman, and Danni Carusi as well as Susan Goobie from Children's Hospital.
Ethan Brovman - SCA Early career investigator award for his presentation entitled “ Risk Factors for Post-operative Reintubation after CABG: a bi-institutional study. ”
Danny Muehlschlegel - Society of Cardiovascular Anesthesiologists (SCA) Kaplan Leadership Development Award
‌
Research Retreat
Date: Thursday May 30th, 2019
Time: 2:00 PM to 8:00 PM
Location:  60 Fenwood Road, Hale 3 Large Conference Room

For more event details, including the full agenda, and to RSVP click here .
Agenda

2:00 PM
Welcome from Dr. Danny Muehlschlegel,  MD, MMSc, FAHA

2:15 - 2:35 PM
iHub Innovations talk with  Chris Coburn  and  Dan Castro

2:40 - 3:00 PM
Biobank talk:  Elizabeth Karlson , Co-Investigator for the Biobank  |Director of the Rheumatic Disease Epidemiology Section of Clinical Sciences, BWH |Professor of medicine at Harvard Medical School

3:00 - 3:30 PM
Keynote talk:  Stuart Forman  | Professor of Anesthesia, Dept. of Anesthesia, Critical Care & Pain Medicine, MGH

3:35 - 3:55 PM
LabArchives , electronic lab notebook talk: Lynn Simpson and Christine Lilian

4:00 - 4:20 PM
Ethics talk: Jessica Ripton, Partners IRB Director

4:30 - 5:30 PM
PI’s give lab/project overviews (Ignite - 5mins/10slides, 12 Presenters)

5:35 - 6:00 PM
Posters session and socializing

6:00 - 7:45 PM
Speed dating hackathon

7:50 PM
Closing remarks
Is your investigator profile featured on our research website ?
If not, please send a recent headshot, along with any relevant information you would like to include in your profile to Andie McHardy-Blaser . Please look at the investigator profiles that are already on the site to give you an idea of the work you may want to highlight.
Featured Investigator
We're looking to feature a new investigator for each edition of this newsletter. This will be a good way to get to know our talented team of researchers and learn a little bit about what they're working on.
Dr. Deborah Culley

Dr. Culley is living the dream. When asked what research she would want to conduct if there were no financial or time restrictions; Dr. Culley responded that she was already doing it. As an innovative leader in the study of post-operative delirium and post-operative cognitive impairment Dr. Culley has worked with national experts to develop new guidelines for preoperative cognitive screening of older patients undergoing elective surgery, something we have already implemented at BWH. Her pioneering research extends from the bench to the bedside and back again; utilizing animal models and clinical studies, Dr. Culley works with Dr. Crosby to investigate how pre-existing cognitive impairment impacts cognition post-operatively. Her passion extends not only to research and clinical care but also to education and service. She is a Director of the American Board of Anesthesiology, an Executive Editor for Anesthesiology, past president of the Society for Neuroscience in Anesthesiology and Critical Care, chair of the Academic Anesthesiology Committee of the American Society of Anesthesiologists, former chair of the Committee on Continuing Certification (3C) of the American Board of Medical Specialities and is included as a “Best Doctor” in national rankings. Asked how she did it all and raised a family, she responded that it was her children that helped her to find the balance and keep her head in the moment. Now that her two children have grown up she looks forward to spending time with her two grandchildren Joshua aged 10 years and 20 month old LIam as well as making some time for boating at their family vacation home on Squam Lake in NH.
2019 BWH Research
Appreciation Celebration
Date/time : Wednesday, June 26, from 5 – 6:30 PM
Location : the Hale Café Atrium 

All researchers in the department/division of Anesthesia, are invited to the 2019 BWH Research Appreciation Celebration!

Dr. Betsy Nabel, members of the ORC, and the BRI Executive Committee will be in attendance to recognize BWH's exceptional researchers as well as make several exciting announcements that you won’t want to miss!

There will be snacks, drinks, festive games, swag, prizes and more! 

Finding Funding
Featured Opportunities
Anesthesiology Department Seed funding
Deadline: Rolling
Funding: up to $10,000 
Eligibility: Lecturer, Instructor, Assistant, or Associate Professor at the time of award funding
•   Goal: Support clinical, translational, or basic science research and project development
•   Prerequisites: 
–   Grantee should have a mentoring plan (senior mentor or mentoring team in area of proposed investigation)
–   Grantee should have a career development plan
Up to 5 seed grants will be awarded in 2019. Grant recipients are required to present their work to the Research Leadership Committee before the start of the project and to the Department at the conclusion of their grant.
Research Development
Grand Rounds
Upcoming dates:

July 24, 2019
August 21, 2019

More details to follow in our June newsletter.
Publications
Cognitive impairment and postoperative outcomes in patients undergoing primary total hip arthroplasty: A systematic review.
Viramontes O, Luan Erfe BM, Erfe JM, Brovman EY , Boehme J, Bader AM, Urman RD.
J Clin Anesth. 2019 Sep;56:65-76. doi: 10.1016/j.jclinane.2019.01.024. Epub 2019 Jan 28. Review.

Incidence, risk factors, and consequences of residual neuromuscular block in the United States: The prospective, observational, multicenter RECITE-US study.
Saager L, Maiese EM, Bash LD, Meyer TA, Minkowitz H, Groudine S, Philip BK , Tanaka P, Gan TJ, Rodriguez-Blanco Y, Soto R, Heisel O.
J Clin Anesth. 2019 Aug;55:33-41. doi: 10.1016/j.jclinane.2018.12.042. Epub 2018 Dec 27.

Kovacheva VP, Brovman EY, Greenberg P, Song E, Palanisamy A, Urman RD.
Anesth Analg. 2019 Jun;128(6):1199-1207. doi: 10.1213/ANE.0000000000003395

Maintenance of Certification: Comment.
Cole DJ, Culley DJ , Fahy BG, Warner DO.
Anesthesiology. 2019 Jun;130(6):1091-1092. doi: 10.1097/ALN.0000000000002723. No abstract available

Wanderer JP, Rathmell JP .
Anesthesiology. 2019 Jun;130(6):A17. doi: 10.1097/ALN.0000000000002768. No abstract available. 

Arriaga AF , Sweeney RE, Clapp JT, Muralidharan M, Burson RC 2nd, Gordon EKB, Falk SA, Baranov DY, Fleisher LA.
Anesthesiology. 2019 Jun;130(6):1039-1048. doi: 10.1097/ALN.0000000000002649.

In Search of Answers and Technology to Better Identify the Bleeding and the Hypercoagulable Patient Phenotype-The Need for Improved Assessment of Deranged Coagulation Beyond Our Current Coagulation Tests.
Frendl G .
Crit Care Med. 2019 Jun;47(6):876-877. doi: 10.1097/CCM.0000000000003754. No abstract available. 

Nanoparticle-biomolecular corona: A new approach for the early detection of non-small-cell lung cancer.
Di Domenico M, Pozzi D, Palchetti S, Digiacomo L, Iorio R, Astarita C, Fiorelli A, Pierdiluca M, Santini M, Barbarino M, Giordano A, Di Carlo A, Frati L, Mahmoudi M , Caracciolo G.
J Cell Physiol. 2019 Jun;234(6):9378-9386. doi: 10.1002/jcp.27622. Epub 2018 Dec 5.

Investigation of intraoperative dosing patterns of neuromuscular blocking agents.
Palsen S, Wu A, Beutler SS, Gimlich R, Yang HK, Urman RD .
J Clin Monit Comput. 2019 Jun;33(3):455-462. doi: 10.1007/s10877-018-0186-4. Epub 2018 Aug 9.

Connor CW.
J Clin Monit Comput. 2019 Jun;33(3):445-454. doi: 10.1007/s10877-018-0169-5. Epub 2018 Jun 21.

Ramirez JL, Gasper WJ, Khetani SA, Zahner GJ, Hills NK, Mitchell PT, Sansbury BE , Conte MS, Spite M , Grenon SM.
J Surg Res. 2019 Jun;238:164-174. doi: 10.1016/j.jss.2019.01.038. Epub 2019 Feb 13.

Giannakis N, Sansbury BE , Patsalos A, Hays TT, Riley CO , Han X, Spite M , Nagy L.
Nat Immunol. 2019 Jun;20(6):765-767. doi: 10.1038/s41590-019-0401-6.

Birnbach DJ, Bateman BT .
Obstet Gynecol Clin North Am. 2019 Jun;46(2):329-337. doi: 10.1016/j.ogc.2019.01.015. Review.

Tu Y, Jung M, Gollub RL, Napadow V, Gerber J, Ortiz A, Lang C, Mawla I, Shen W, Chan ST, Wasan AD, Edwards RR , Kaptchuk TJ, Rosen B, Kong J.
Pain. 2019 Jun;160(6):1308-1318. doi: 10.1097/j.pain.0000000000001507.

Blevins Peratikos M, Weeks HL, Pisansky AJB, Yong RJ, Stringer EA.
Pain Med. 2019 May 23. pii: pnz083. doi: 10.1093/pm/pnz083. [Epub ahead of print]

Toomer KA, Yu M, Fulmer D, Guo L, Moore KS, Moore R, Drayton KD, Glover J, Peterson N, Ramos-Ortiz S, Drohan A, Catching BJ, Stairley R, Wessels A, Lipschutz JH, Delling FN, Jeunemaitre X, Dina C, Collins RL, Brand H, Talkowski ME, Del Monte F, Mukherjee R, Awgulewitsch A, Body S , Hardiman G, Hazard ES, da Silveira WA, Wang B, Leyne M, Durst R, Markwald RR, Le Scouarnec S, Hagege A, Le Tourneau T, Kohl P, Rog-Zielinska EA, Ellinor PT, Levine RA, Milan DJ, Schott JJ, Bouatia-Naji N, Slaugenhaupt SA, Norris RA.
Sci Transl Med. 2019 May 22;11(493). pii: eaax0290. doi: 10.1126/scitranslmed.aax0290.

Engle AM, Chen Y, Marascalchi B, Wilkinson I, Abrams WB, He C , Yao AL, Adekoya P, Cohen ZO, Cohen SP.
Pain Med. 2019 May 17. pii: pnz097. doi: 10.1093/pm/pnz097. [Epub ahead of print]

Harris MJ, Brovman EY, Urman RD.
J Clin Anesth. 2019 May 14;58:61-71. doi: 10.1016/j.jclinane.2019.05.010. [Epub ahead of print]

Mhyre JM, Bateman BT
Anesthesiology. 2019 May 13. doi: 10.1097/ALN.0000000000002794. [Epub ahead of print] No abstract available. 

Use of real-world evidence from healthcare utilization data to evaluate drug safety during pregnancy.
Huybrechts KF, Bateman BT , Hernández-Díaz S.
Pharmacoepidemiol Drug Saf. 2019 May 10. doi: 10.1002/pds.4789. [Epub ahead of print] Review.

Recent Progress on Discovery of Sirt2 Inhibitors for the Treatment of Various Cancers.
Wang T, Xu Z, Lu Y, Qi B , Bai L, Liu W, Zhang C, Jiang Z.
Curr Top Med Chem. 2019 May 9. doi: 10.2174/1568026619666190510103416. [Epub ahead of print]

Quality, cost and teamwork: Adding the human element to perioperative services. Proceedings of the Association of Anesthesia Clinical Directors (AACD) Annual Perioperative Summit, 2019.
Serdiuk AA, Urman RD .
J Clin Anesth. 2019 May 9;58:55-56. doi: 10.1016/j.jclinane.2019.04.028. [Epub ahead of print] No abstract available. 

Peptide-Based Autophagic Gene and Cisplatin Co-delivery Systems Enable Improved Chemotherapy Resistance.
Lin YX, Wang Y , An HW, Qi B , Wang J , Wang L, Shi J , Mei L, Wang H.
Nano Lett. 2019 May 8;19(5):2968-2978. doi: 10.1021/acs.nanolett.9b00083. Epub 2019 Apr 3.

Sex differences in negative affect and postoperative pain in patients undergoing total knee arthroplasty.
Nandi M, Schreiber KL, Martel MO, Cornelius M , Campbell CM, Haythornthwaite JA, Smith MT Jr, Wright J, Aglio LS, Strichartz G, Edwards RR.
Biol Sex Differ. 2019 May 6;10(1):23. doi: 10.1186/s13293-019-0237-7.

Toxic Ingestion of Acetaminophen and Acetylsalicylic Acid in a Parturient at 33 Weeks Gestation: A Case Report.
Reale SC , Gray KJ, Boyer EW, Arce DY, Farber MK .
A A Pract. 2019 May 1;12(9):302-304. doi: 10.1213/XAA.0000000000000915.

Lumbar Spinal Stenosis Severity by CT or MRI Does Not Predict Response to Epidural Corticosteroid versus Lidocaine Injections.
Perez FA, Quinet S, Jarvik JG, Nguyen QT, Aghayev E, Jitjai D, Hwang WD, Jarvik ER, Nedeljkovic SS , Avins AL, Schwalb JM, Diehn FE, Standaert CJ, Nerenz DR, Annaswamy T, Bauer Z, Haynor D, Heagerty PJ, Friedly JL.
AJNR Am J Neuroradiol. 2019 May;40(5):908-915. doi: 10.3174/ajnr.A6050. Epub 2019 May 2.

Concepts for the Development of Anesthesia-Related Patient Decision Aids.
Urman RD , Southerland WA, Shapiro FE, Joshi GP.
Anesth Analg. 2019 May;128(5):1030-1035. doi: 10.1213/ANE.0000000000003804.

Monitoring Cardiac Output: A Big Problem for Little Patients.
Wanderer JP, Rathmell JP .
Anesthesiology. 2019 May;130(5):A19. doi: 10.1097/ALN.0000000000002749. No abstract available. 

Perioperative Quality Initiative consensus statement on preoperative blood pressure, risk and outcomes for elective surgery.
Sanders RD, Hughes F, Shaw A, Thompson A, Bader A , Hoeft A, Williams DA, Grocott MPW, Mythen MG, Miller TE, Edwards MR; Perioperative Quality Initiative-3 Workgroup; POQI chairs; Physiology group; Preoperative blood pressure group; Intraoperative blood pressure group; Postoperative blood pressure group.
Br J Anaesth. 2019 May;122(5):552-562. doi: 10.1016/j.bja.2019.01.018. Epub 2019 Mar 2.


Point-of-care coagulation testing for obstetric hemorrhage: time for a theranostic approach?
Reale SC , Farber MK .
Int J Obstet Anesth. 2019 May;38:1-3. doi: 10.1016/j.ijoa.2019.04.001. Epub 2019 Apr 5. No abstract available. 

Accidental dural puncture during labor analgesia and obstetric outcomes in nulliparous women.
Shea K, Choi L, Jagannathan D, Elterman K, Robinson J, Kodali B, Huang CC, Palanisamy A.
Int J Obstet Anesth. 2019 May;38:46-51. doi: 10.1016/j.ijoa.2018.12.001. Epub 2018 Dec 12.

Preoperative Psychosocial and Psychophysical Phenotypes as Predictors of Acute Pain Outcomes After Breast Surgery.
Schreiber KL , Zinboonyahgoon N, Xu X , Spivey T, King T, Dominici L, Partridge A, Golshan M, Strichartz G , Edwards RR .
J Pain. 2019 May;20(5):540-556. doi: 10.1016/j.jpain.2018.11.004. Epub 2018 Nov 23.

Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration.
Giannakis N, Sansbury BE , Patsalos A, Hays TT, Riley CO , Han X, Spite M , Nagy L.
Nat Immunol. 2019 May;20(5):626-636. doi: 10.1038/s41590-019-0356-7. Epub 2019 Apr 1. Erratum in: Nat Immunol. 2019 May 2;:. 

The Association Between Daily Physical Activity and Pain Among Patients with Knee Osteoarthritis: The Moderating Role of Pain Catastrophizing.
Lazaridou A, Martel MO, Cornelius M, Franceschelli O, Campbell C, Smith M, Haythornthwaite JA, Wright JR, Edwards RR .
Pain Med. 2019 May 1;20(5):916-924. doi: 10.1093/pm/pny129.

Fast-Track Pancreaticoduodenectomy: Factors Associated with Early Discharge.
Mahvi DA, Pak LM, Bose SK, Urman RD , Gold JS, Whang EE.
World J Surg. 2019 May;43(5):1332-1341. doi: 10.1007/s00268-019-04916-0.

Essential Elements for Enhanced Recovery After Intra-Abdominal Surgery.
Elhassan A, Elhassan I, Elhassan A, Sekar KD, Rubin RE, Urman RD , Cornett EM, Kaye AD.
Curr Pain Headache Rep. 2019 Apr 30;23(5):35. doi: 10.1007/s11916-019-0772-2. Review.

Guest Editorial: Physician Guidance on the Use of Off-Labeled Drugs in Intrathecal Drug Delivery Systems for Chronic Pain.
Deer T, Kim P, Pope JE, Hayek S, McDowell G, Mekhail N, Diwan S, Saulino M, Moeschler S, Schultz D, Gritsenko K, Prager J, Peterson EA, Staats P, Poree L, Fishman MA, Vallejo R, Calodney A, Slavin K, de Leon Cassadala O, Levy R, Buvanendran A, Sitzman BT, Sayed D, Ferrante FM, Kloth D, Gilligan CJ , Kapural L, Kloster DR, Leong M, Rosenow JM, Lamer TJ, Stearns L.
Neuromodulation. 2019 Apr 30. doi: 10.1111/ner.12961. [Epub ahead of print] No abstract available. 

Consensus clinical scoring for suspected perioperative immediate hypersensitivity reactions.
Hopkins PM, Cooke PJ, Clarke RC, Guttormsen AB, Platt PR, Dewachter P, Ebo DG, Garcez T, Garvey LH, Hepner DL , Khan DA, Kolawole H, Kopac P, Krøigaard M, Laguna JJ, Marshall SD, Mertes PM, Rose MA, Sabato V, Savic LC, Savic S, Takazawa T, Volcheck GW, Voltolini S, Sadleir PHM.
Br J Anaesth. 2019 Apr 24. pii: S0007-0912(19)30191-6. doi: 10.1016/j.bja.2019.02.029. [Epub ahead of print]

The use of drug provocation testing in the investigation of suspected immediate perioperative allergic reactions: current status.
Garvey LH, Ebo DG, Krøigaard M, Savic S, Clarke R, Cooke P, Dewachter P, Garcez T, Guttormsen AB, Hopkins PM, Hepner DL , Khan DA, Kolawole H, Kopac P, Marshall S, Mertes PM, Platt P, Rose M, Sabato V, Sadleir P, Savic L, Scherer K, Takazawa T, Volcheck GW, Voltolini S, Laguna JJ.
Br J Anaesth. 2019 Apr 23. pii: S0007-0912(19)30220-X. doi: 10.1016/j.bja.2019.03.018. [Epub ahead of print]

Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells.
Botten N, Hodges RR, Li D, Bair JA, Shatos MA, Utheim TP, Serhan CN , Dartt DA.
FASEB J. 2019 Apr 23:fj201802467R. doi: 10.1096/fj.201802467R. [Epub ahead of print]

Anesthesiology Control Tower-Feasibility Assessment to Support Translation (ACTFAST): Mixed-Methods Study of a Novel Telemedicine-Based Support System for the Operating Room.
Murray-Torres T, Casarella A, Bollini M, Wallace F , Avidan MS, Politi MC.
JMIR Hum Factors. 2019 Apr 23;6(2):e12155. doi: 10.2196/12155.

Nanobuffering of pH-Responsive Polymers: A Known but Sometimes Overlooked Phenomenon and Its Biological Applications.
Tao W , Wang J , Parak WJ, Farokhzad OC , Shi J .
ACS Nano. 2019 Apr 15. doi: 10.1021/acsnano.9b01696. [Epub ahead of print]

Impact of Automated Time-released Reminders on Patient Preparedness for Colonoscopy.
Nayor J, Feng A , Qazi T, Hurwitz S, Saltzman JR.
J Clin Gastroenterol. 2019 Apr 15. doi: 10.1097/MCG.0000000000001211. [Epub ahead of print]

Inappropriate opioid prescription after surgery.
Neuman MD, Bateman BT , Wunsch H.
Lancet. 2019 Apr 13;393(10180):1547-1557. doi: 10.1016/S0140-6736(19)30428-3. Review.

Optimal postoperative pain management: redefining the role for opioids.
Hollmann MW, Rathmell JP , Lirk P .
Lancet. 2019 Apr 13;393(10180):1483-1485. doi: 10.1016/S0140-6736(19)30854-2. No abstract available. 

Perioperative Pain Management in the Critically Ill Patient.
Czernicki M, Kunnumpurath S, Park W, Kunnumpurath A, Kodumudi G, Tao J, Kodumudi V, Vadivelu N, Urman RD .
Curr Pain Headache Rep. 2019 Apr 11;23(5):34. doi: 10.1007/s11916-019-0771-3. Review.

Metabolic and the Surgical Stress Response Considerations to Improve Postoperative Recovery.
Helander EM, Webb MP, Menard B, Prabhakar A, Helmstetter J, Cornett EM, Urman RD , Nguyen VH, Kaye AD.
Curr Pain Headache Rep. 2019 Apr 11;23(5):33. doi: 10.1007/s11916-019-0770-4. Review.

Orchestrated biomechanical, structural, and biochemical stimuli for engineering anisotropic meniscus.
Zhang ZZ, Chen YR, Wang SJ, Zhao F, Wang XG, Yang F, Shi JJ , Ge ZG, Ding WY, Yang YC, Zou TQ, Zhang JY, Yu JK, Jiang D.
Sci Transl Med. 2019 Apr 10;11(487). pii: eaao0750. doi: 10.1126/scitranslmed.aao0750.

Drug Delivery Strategies for the Treatment of Metabolic Diseases.
Shi S, Kong N, Feng C, Shajii A, Bejgrowicz C, Tao W, Farokhzad OC.
Adv Healthc Mater. 2019 Apr 8:e1801655. doi: 10.1002/adhm.201801655. [Epub ahead of print] Review.

Preemptive ECMO Cannulation in a Patient with Severe Left Ventricular Systolic Dysfunction Undergoing Cesarean Delivery.
Bui P , Mascaro PG, Henao-Mejia J, Patel S.
Case Rep Anesthesiol. 2019 Apr 8;2019:2623608. doi: 10.1155/2019/2623608. eCollection 2019.

Artificial Intelligence and Machine Learning in Anesthesiology.
Connor CW .
Anesthesiology. 2019 Apr 5. doi: 10.1097/ALN.0000000000002694. [Epub ahead of print]

Assessment of Health Care Utilization and Cost of Targeted Drug Delivery and Conventional Medical Management vs Conventional Medical Management Alone for Patients With Cancer-Related Pain.
Stearns LJ, Narang S , Albright RE Jr, Hammond K, Xia Y, Richter HB, Paramanandam GK, Haagenson KK, Doth AH.
JAMA Netw Open. 2019 Apr 5;2(4):e191549. doi: 10.1001/jamanetworkopen.2019.1549.

Prediction of Discharge Destination Following Major Hepatectomy.
Mahvi DA, Pak LM, Fields AC, Urman RD , Gold JS, Whang EE.
HPB (Oxford). 2019 Apr 4. pii: S1365-182X(19)30475-7. doi: 10.1016/j.hpb.2019.03.354. [Epub ahead of print]

Commentary: At long last-Cerebral oximetry-based goal directed therapy to prevent postoperative cognitive decline is here.
Aglio LS, Gugino LD, Mizuguchi KA.
J Thorac Cardiovasc Surg. 2019 Apr 4. pii: S0022-5223(19)30744-5. doi: 10.1016/j.jtcvs.2019.03.066. [Epub ahead of print] No abstract available. 

In Response.
Markley JC, Farber MK , Perlman NC, Carusi DA.
Anesth Analg. 2019 Apr;128(4):e57-e58. doi: 10.1213/ANE.0000000000004050. No abstract available. 

Benefits of Knowing Your Risks: A Step Toward Shared Surgical Decision-Making and High-Value Care.
Allen MB, Bader AM.
Anesth Analg. 2019 Apr;128(4):607-609. doi: 10.1213/ANE.0000000000003978. No abstract available. 

Stop Interfering! Intraoperative Management of ICDs.
Wanderer JP, Rathmell JP .
Anesthesiology. 2019 Apr;130(4):A15. doi: 10.1097/ALN.0000000000002680. No abstract available. 

The siRNAsome: A Cation-Free and Versatile Nanostructure for siRNA and Drug Co-delivery.
Zheng M, Jiang T, Yang W, Zou Y, Wu H, Liu X, Zhu F, Qian R, Ling D, McDonald K, Shi J, Shi B.
Angew Chem Int Ed Engl. 2019 Apr 1;58(15):4938-4942. doi: 10.1002/anie.201814289. Epub 2019 Mar 3.

Identifying brain regions associated with the neuropathology of chronic low back pain: a resting-state amplitude of low-frequency fluctuation study.
Zhang B, Jung M, Tu Y, Gollub R, Lang C, Ortiz A, Park J, Wilson G, Gerber J, Mawla I, Chan ST, Wasan A, Edwards R , Lee J, Napadow V, Kaptchuk T, Rosen B, Kong J.
Br J Anaesth. 2019 Apr 1. pii: S0007-0912(19)30143-6. doi: 10.1016/j.bja.2019.02.021. [Epub ahead of print]

Opioid-free anaesthesia: Con: it is too early to adopt opioid-free anaesthesia today.
Lirk P, Rathmell JP.
Eur J Anaesthesiol. 2019 Apr;36(4):250-254. doi: 10.1097/EJA.0000000000000965. No abstract available. 

What do you expect? Catastrophizing mediates associations between expectancies and pain-facilitatory processes.
Carriere JS , Martel MO, Meints SM, Cornelius MC, Edwards RR.
Eur J Pain. 2019 Apr;23(4):800-811. doi: 10.1002/ejp.1348. Epub 2019 Jan 9.

Acupuncture for Chronic Low Back Pain: Recommendations to Medicare/Medicaid from the Society for Acupuncture Research.
Mao JJ, Davis RT, Coeytaux R, Hullender-Rubin L, Kong JT , MacPherson H, Napadow V, Schnyer R, Wayne PM, Witt C, Harris R.
J Altern Complement Med. 2019 Apr;25(4):367-369. doi: 10.1089/acm.2019.29067.jjm. Epub 2019 Mar 30. No abstract available. 

The Use of Regional or Local Anesthesia for Carotid Endarterectomies May Reduce Blood Loss and Pulmonary Complications.
Malik OS, Brovman EY, Urman RD .
J Cardiothorac Vasc Anesth. 2019 Apr;33(4):935-942. doi: 10.1053/j.jvca.2018.08.195. Epub 2018 Aug 23.

Understanding Echo Through Embryology.
Burbano N .
J Cardiothorac Vasc Anesth. 2019 Apr;33(4):1048-1049. doi: 10.1053/j.jvca.2018.06.029. Epub 2018 Jul 5. No abstract available. 

Outcomes of intraparenchymal hemorrhage after direct oral anticoagulant or vitamin K antagonist therapy: A systematic review and meta-analysis.
DiRisio AC, Harary M, Muskens IS, Yunusa I, Gormley WB, Aglio LS , Smith TR, Connors JM, Mekary RA, Broekman MLD.
J Clin Neurosci. 2019 Apr;62:188-194. doi: 10.1016/j.jocn.2018.11.032. Epub 2018 Nov 22.

AAPT Diagnostic Criteria for Peripheral Neuropathic Pain: Focal and Segmental Disorders.
Freeman R, Edwards R , Baron R, Bruehl S, Cruccu G, Dworkin RH, Haroutounian S.
J Pain. 2019 Apr;20(4):369-393. doi: 10.1016/j.jpain.2018.10.002. Epub 2018 Dec 5.

A Review of Spinal and Peripheral Neuromodulation and Neuroinflammation: Lessons Learned Thus Far and Future Prospects of Biotype Development.
Chakravarthy KV, Xing F , Bruno K, Kent AR, Raza A, Hurlemann R, Kinfe TM.
Neuromodulation. 2019 Apr;22(3):235-243. doi: 10.1111/ner.12859. Epub 2018 Oct 12. Review.

The relationship between catastrophizing and altered pain sensitivity in patients with chronic low-back pain.
Meints SM , Mawla I, Napadow V, Kong J, Gerber J, Chan ST, Wasan AD, Kaptchuk TJ, McDonnell C, Carriere J , Rosen B, Gollub RL, Edwards RR .
Pain. 2019 Apr;160(4):833-843. doi: 10.1097/j.pain.0000000000001461.

Pain management after laparoscopic hysterectomy: systematic review of literature and PROSPECT recommendations.
Lirk P , Thiry J, Bonnet MP, Joshi GP, Bonnet F; PROSPECT Working Group.
Reg Anesth Pain Med. 2019 Apr;44(4):425-436. doi: 10.1136/rapm-2018-100024. Epub 2019 Feb 3.

Anesthesia considerations and post-operative pain management in pregnant women with chronic opioid use.
Soens MA, He J, Bateman BT.
Semin Perinatol. 2019 Apr;43(3):149-161. doi: 10.1053/j.semperi.2019.01.004. Epub 2019 Jan 14. Review.
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