November/December 2020 Newsletter
In This Issue:
  • President's Message
  • Board of Director's Update
  • R&E Foundation Update
  • Education - We Need Your Ideas
  • Congratulations to the Kansas City Veteran Affairs Primary Care Clinical Pharmacy Program
  • Public Policy Update
  • Pharmacist Continuing Education Articles
  • Alternative Therapies for the Treatment of Psychiatric Disorders
  • Therapeutic Challenges to Treating Sodium Disorders: A Review of Hyponatremia and Hypernatremia 
  • Featured Clinical Topic: Infectious Disease/Vaccines
  • Core Elements of Hospital Antimicrobial Stewardship Programs: Updates from the 2019 CDC ASP Report  
  • Update on New Antibiotics with Activity Against Multi-Drug Resistant Organisms
  • A Comparison of Three Recent Human Coronavirus Strains: SARS-CoV, MERS-CoV, and SARS-CoV-2
  • A Vaccine to End a Pandemic?
  • Clinical Features, HIV Management, and Outcomes of Patients Coinfected with HIV and SARS-CoV-2
  • Affiliate Chapter News and Events
  • Upcoming Newsletter Info
President's Message
By Davina Dell-Steinbeck, PharmD, BCPS; SSM Health St. Mary’s Hospital
“Life can only be understood backwards; but it must be lived forwards.” - Søren Kierkegaard

At the end of each year, I feel it is important to reflect on what I have accomplished. In reflecting on this year, MSHP has accomplished so much despite the restraints of the pandemic and should be proud. Here is a list of some of what we accomplished during our 50th year:

  • MSHP Operating Policies and Procedures updated and approved
  • Developed Tech-Check-Tech guidance document
  • Revamped Communications and Website committees and merged them into the Website and Social Media committee and ...
Board of Director's Update
By Christina Stafford, PharmD, BCPS- MSHP President- Elect; CoxHealth, Springfield 

September
  • Strategic Planning session set for October 2nd. Main strategic goals will be advocacy, education, and membership.
  • ASHP asked MSHP to sign on to a letter of support of USPS medication delivery to Congress. Presidents and Secretary voted to sign on due to short timeline
  • The Board voted to approve Website/Social Media Committee members administrative access to the MSHP social media platforms.
  • P1 students will have SSHP membership fees waived this year
  • New ASHP Section of Community Pharmacy Practitioners. Davina requested that names of candidates be sent to her.

October
  • Davina recognized the STLCOP and UMKC SSHP chapters for their official recognition as ASHP-SSHP chapters.
  • Discussed Strategic Plan. Will vote to finalize at November meeting.
  • Approved 20% membership discounts for new and renewing members during Pharmacy Week and through the end of October
  • House of Delegates- call for nominations to be sent out
  • Planning for Pharmacy Week- social media posts promoting Pharmacy Week, two contests for prizes
  • Discussed email from ASHP regarding how MSHP is addressing diversity/inclusion/equity in our organization and healthcare. Planning to add to the Strategic Plan.
  • Presidential Officers Retreat will be done virtually next month. Davina, Alex and Christina to attend.
R&E Foundation Update
By: Jackie A. Harris, PharmD, BCPS; Executive Director, MSHP Research & Education Foundation; Christian Hospital
Best Practices Award Winner – A Pharmacist-Driven Penicillin Allergy Overhaul 

Becca Nolen, Infectious Diseases and Antimicrobial Stewardship Pharmacist at SSM Health-St. Mary’s Hospital received the Best Practices Award during the Virtual KCHP/MSHP Spring Meeting for her project entitled “A Pharmacist-Driven Penicillin Allergy Overhaul.”



MSHP R&E Call for Award Nominations 

MSHP R&E Foundation is currently accepting submissions and nominees for several awards.

Education - Your Ideas Count!
We are looking for your ideas and thoughts about additional educational sessions that we can do for you. Please take a minute and provide us one idea that we can get content for to present to our members.

Here are just a few that we have been thinking about:

  • Pediatric topics
  • Panel on medical cannabis
  • Panel for students on how to apply and match for residency
  • Late breaking trials in CVD, COVID19, transplant, etc in regards to implications on acute care and transitions of care.
  • A panel discussing successes (or areas for improvement) in pharmacy management in the setting of COVID19​ that you could use as a list for potential submissions.

Additionally, we are open to all topic ideas for webinars.
Congratulations to the Kansas City Veteran Affairs Primary Care Clinical Pharmacy Program!
The Kansas City Veteran Affairs (VA) Primary Care Clinical Pharmacy Program received the VA Clinical Pharmacy Patient Aligned Care Team Platinum Practice Designation! This distinguished National designation recognizes the program as a shining example of exceptional team based care and what it can do to improve Veteran access and quality of care. The Kansas City VA program is one of two programs that have received the designation! The dedication and commitment of Kansas City VA Primary Care Clinical Pharmacy Specialists is an excellent example of Veteran centric care!
Public Policy Update
Focus on the Possible 

By Nathan Hanson, PharmD, MS, BCPS, Health Trust Supply Chain
As we push for provider status and other new possibilities, let’s focus on actually doing the things that we are already allowed to do! 

Productive Dissatisfaction
It is good that we are not satisfied with the status quo because that fuels us to continue to create new possibilities. It reminds us that our patients need the services that we can provide, so we need to keep pushing for the ability to provide them. However, as we knock on the doors of new possibilities we may be missing out on the possibilities already available to us!
Alternative Therapies for the Treatment of Psychiatric Disorders

By: Jennifer Tran, PharmD; PGY1 Pharmacy Resident

Mentor: Lisa Sterling, PharmD, BCPS, BCGP; Residency Program Director/Clinical Pharmacy Specialist, Mercy Hospital – Springfield, MO
Psychiatric disorders affect 450 million people across the world.1 According to the World Health Organization (WHO), one in four people will have one or more mental disorders in their lifetime.1 Listed in Table 1 are common risk factors for psychiatric disorders.

Medications used to treat a variety of major psychiatric disorders include antipsychotics, antidepressants, mood stabilizers, and anti-anxiety, however the efficacy of these medications varies and many of them have significant adverse effects.

Program Number: 2020-11-03
Approval Dates: December 1, 2020 to May 1, 2021
Approved Contact Hours: 1 hour
Therapeutic Challenges to Treating Sodium Disorders: A Review of Hyponatremia and Hypernatremia 

By: Gadison Quick, PharmD; PGY1 Pharmacy Resident

Mentor: Kerry Yamada, PharmD, BCPS; PGY-1 Pharmacy Residency Coordinator, Truman Medical Center – Kansas City, MO
Electrolyte disorders like hyponatremia or hypernatremia are not diseases, but rather a pathophysiologic process indicating a disturbance in water homeostasis. Sodium is abundantly used throughout every major body system to maintain homeostasis. One of sodium’s many vital roles is to help maintain normal fluid volumes throughout various intracellular and extracellular compartments. Sodium and blood osmolarity are highly dependent upon each other, hence the phrase “where goes water, goes salt”. Physiologically, we see if the serum sodium concentrations (SNa) are elevated (>145mEq/L), fluid will move into plasma to dilute the high sodium concentration.

Program Number: 2020-11-01
Approval Dates: December 1, 2020 to May 1, 2021
Approved Contact Hours: 1 hour
Featured Clinical Topic: Infectious Disease/Vaccines
Core Elements of Hospital Antimicrobial Stewardship Programs: Updates from the 2019 CDC ASP Report  

By: Rexhian Brisku, PharmD Candidate 2021, St. Louis College of Pharmacy at the University of Health Sciences and Pharmacy in St. Louis; Elizabeth Neuner, PharmD, BCPS, BCIDP, Barnes-Jewish Hospital – St. Louis
In 2014, the Centers for Disease Control and Prevention (CDC) released the Core Elements of Hospital Antimicrobial Stewardship Programs (Core Elements) to provide guidance and structure for antimicrobial stewardship programs (ASPs). Regulatory bodies including Centers for Medicare and Medicaid Services and The Joint Commission have since incorporated the Core Elements into accreditation standards. Despite advancements in stewardship, antibiotic resistance is still increasing and remains a public health hazard. The updated 2019 Antibiotic Resistance Threats Report by the CDC estimates 2.8 million cases of resistant infections lead to 35,000 deaths each year.
Update on New Antibiotics with Activity Against Multi-Drug Resistant Organisms

By: Jesse Smith, PharmD Candidate 2021, St. Louis College of Pharmacy at the University of Health Sciences and Pharmacy in St. Louis

Mentor: Bryan Lizza, PharmD, MS, BCCCP, Barnes-Jewish Hospital – St. Louis
In the United States, more than 2.8 million antibiotic-resistant infections occur annually, leading to more than 35,000 deaths. Despite recent initiatives in infection prevention and antibiotic conservation, multi-drug resistant organisms (MDROs) continue to be a global health crisis as mortality and morbidity from MDROs continue to rise. As a result of this need for new antibiotic therapy, advancements in antimicrobial development have led to several recently approved antibiotics. Pharmacists will play a vital role in ensuring appropriate use of these new novel agents as well as understanding their mechanisms of action and their important clinical features. The purpose of this article is to describe new antibiotics with activity towards MDROs and summarize important studies that led to their FDA approval.
A Comparison of Three Recent Human Coronavirus Strains: SARS-CoV, MERS-CoV, and SARS-CoV-2

By: Abbey Jin, Ashley Jose, and Miriam Bisada, PharmD Candidates Class of 2021; St. Louis College of Pharmacy at University of Health Sciences and Pharmacy in St. Louis

Mentor: Yvonne Burnett, PharmD, BCIDP; Assistant Professor, St. Louis College of Pharmacy at University of Health Sciences and Pharmacy in St. Louis; Infectious Diseases Clinical Pharmacist, Missouri Baptist Medical Center
Coronaviridae are a diverse family of single-stranded RNA viruses that typically infect mammalian and avian hosts. Structurally, coronaviridae are spherical in nature with protruding spikes on the surface, resembling clubs. First discovered in humans in the 1960s, the coronavirus family has since rapidly mutated to include seven different human coronaviruses (hCoV), which can be broken down into four sub-groups: alpha, beta, gamma, and delta, alpha and beta being the most common. Notably in the 21st century, three life-threatening coronavirus infections have emerged: Middle East Respiratory Syndrome (MERS), Severe Acute Respiratory Syndrome (SARS), and Coronavirus Disease 2019 (COVID-19).
A Vaccine to End a Pandemic?

By: Annalisa Torres, PharmD Candidate 2021; St. Louis College of Pharmacy at the University of Health Sciences and Pharmacy in St. Louis

Mentor: Paul Juang, PharmD, BCPS, BCCP, FASHP, FCCM; Professor, Department of Pharmacy Practice, St. Louis College of Pharmacy at the University of Health Sciences and Pharmacy in St. Louis
As 2019 drew to a close, the world saw the emergence of a novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease known as Coronavirus-2019 (COVID-19). This highly pathogenic coronavirus was originally identified in Wuhan, China and would eventually spread to the rest of the global population resulting in a modern worldwide pandemic. The increased morbidity and mortality associated with COVID-19 resulted in the need for both the rapid manufacturing and global distribution of a safe and effective vaccine that is unparalleled.1 Due to its highly infectious nature that has resulted in numerous mortalities along with the global economic impact, understanding how SARS-CoV-2 enters the cell is an important factor in vaccine development.
Clinical Features, HIV Management, and Outcomes of Patients Coinfected with HIV and SARS-CoV-2

By: Abbey Jin, PharmD Candidate 2021, St. Louis College of Pharmacy at University of Health Sciences and Pharmacy in St. Louis

Mentor: Alexandria Wilson, Pharm.D., BCPS (AQ-ID); Associate Professor, St. Louis College of Pharmacy at University of Health Sciences and Pharmacy in St. Louis; Clinical Pharmacy Specialist, Infectious Diseases, Washington University Infectious Disease Clinic
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread rapidly across the world since the first known cases arose out of Wuhan, China in late 2019. Coronavirus Disease 2019 (COVID-19) was declared a pandemic on March 11th, 2020. As of the writing of this paper, there have been over 43 million confirmed cases of COVID-19 worldwide, with over 1 million deaths. Patients with underlying health conditions may have different outcomes than patients without comorbidities. In particular, people living with Human Immunodeficiency Virus (PLHIV) have been labelled as a COVID-19 high-risk group due to immunosuppression. In a report from Kanwugu et al., published on July 21st 2020, there have been 378 reported cases of COVID-19 among PLHIV worldwide. This review will summarize the clinical characteristics, HIV management, and outcomes of PLHIV who are infected with SARS-CoV-2.
Greater Kansas City Society of Health-System Pharmacists (GKCSHP) 

President: Ashley Duty, PharmD, MS (ashleymduty@gmail.com)


Mid-Missouri Society of Health-System Pharmacists (MMSHP) 

Like us on Facebook! www.facebook.com/mymmshp/  

President:  Sandy McGraw, PharmD, BCPS (mcgrawa@health.missouri.edu


Saint Louis Society of Health-System Pharmacists (STLSHP) 

President: Gabrielle Gibson, PharmD, BCPS, BCCCP (gabrielle.gibson@bjc.org


Southeast Missouri Society of Health-System Pharmacists (SEMSHP) 


President: Janice Wesbecher, PharmD, BCPS (jbueter@sehealth.org
Upcoming Newsletter Info
Upcoming Featured Clinical Topics 

Jan/Feb 2021 – Endocrinology
Mar/Apr 2021 – Psych/Neuro/Pain
May/June 2021 – CriticalCare/Pulm/EmergencyMed

Submit to: Sarah Cook
Newsletter Submission Deadlines:

Jan/Feb 2021: January 1st
Mar/Apr 2021: February 22nd
May/June 2021: April 26th
Newsletter Submission Guidelines

  • Pharmacists, pharmacy technicians, and pharmacy students in Missouri are eligible to submit content for publication in the MSHP Newsletter. Student submissions need to include pharmacist oversight.

  • Submit content to the current Newsletter Committee Chair on or before the established deadlines.

  • CE and Featured Clinical Topics must be approved by the Newsletter Committee Chair in advance of article submission, to prevent duplicates. Duplicate articles submitted without advanced approval may not be published.

  • Recommended length of submissions for committee, affiliate, college/schools of pharmacy, and student chapter reports is half to one page in length.

  • Recommended length of submissions for featured clinical topics is 1 to 2 pages, without references.

  • Recommended length of CE articles is individualized, based on the amount of CE provided.

  • Recommended length of submission for other categories is 1 to 2 pages.
MSHP Board of Directors & Committee Chairs
2020-2021 Board Members

President:  Davina Dell-Steinbeck

President-Elect: Christina Stafford

Immediate Past President: Alex Oschman

Secretary: Barb Kasper

Treasurer: Elaine Ogden
2020-2021 Committee Chairs

Vendor Relations Board Liaison - Evanna Shopoff

Membership Committee - Kristen Petersen

Public Policy Committee - Nathan Hanson

Newsletter Committee - Sarah Cook

Education and Programming - Rebecca Nolen

Website & Social Media - Bethany Baker
Questions & Comments
If you have any questions, comments, or wish to submit an article to for MSHP Newsletter, please contact the Newsletter Committee Chair (Sarah Cook) or another Newsletter Committee member.

2020-2020 MSHP Newsletter Committee Members
Sarah Cook, PharmD, BCPS (Chair)
Laura Challen, PharmD, MBA, BCPS, BCACP (Vice-Chair)
Yvonne Burnett, PharmD, BCIDP
Gabrielle Gibson, PharmD, BCPS, BCCCP
Rebecca Nolen, PharmD, BCPS, BCIDP, AAHIVP
Hannah Pope, PharmD, BCPS
Emily Shor, PharmD