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Revised Common Rule Cooperative Research Provision Compliance Date is January 20, 2020

As of January 20, 2020, According to the Revised Common Rule’s Cooperative Research Provision (45 CFR 46.114), all institutions located in the United States that are engaged in cooperative research conducted or supported by a Common Rule department or agency must rely upon approval by a Single IRB for the portion of the research conducted in the United States.

As of January 20, 2020, if your UK research project is: federally funded (federal agency list); is considered cooperative (involves more than 1 site/institution); and is non-exempt research, it will most likely fall under this provision and must rely on a Single IRB for review and oversight.

While there are limited exceptions to the requirement, this final provision of the revised Common Rule regulation is intended to streamline research oversight. The Office of Research Integrity (ORI) Reliance Team will help you navigate this new paradigm for Federally-Funded Collaborative Human Research.   Please contact ORI’s Reliance Team at irbreliance@uky.edu or 859-218-1501 if you think your research may fall under this new Cooperative Research Provision requiring Single IRB review.  See the ORI Single IRB Reliance Website for additional information and resources.