Preparedness Pulsepoints | Monitoring USG action on readiness and response
Published by the Johns Hopkins Center for Health Security
Sanjana Ravi, MPH, Editor
March 20, 2018

We're grateful to report that 2017 was a year of exciting new opportunities for the Center and promise for the future of the health security field. In our work we endeavor to study the most pressing problems in the field, to build national and international networks of concerned scientists and health experts, and to share what we discover with policymakers and practitioners in ways that bring about constructive changes. We are inspired by the many possibilities to collaborate with partners around the country and the world on issues at the heart of our mission.

Public Health & Healthcare Preparedness
NEWS
NBAF Update: Little Would Change if USDA Were to Take Over Facility. The NBAF will be a leading bio and agro-defense research facility offering comprehensive research on diseases impacting livestock. Construction remains on track to finish in 2020 and the facility is scheduled to be fully commissioned by 2021. USDA expects to meet the goal of having the building fully operational by December 2022. (The Mercury, 3/18/18)
REPORT
Implementing the Global Health Security Agenda: Progress and Impact from US Government Investments. The information contained in this second annual report, which focuses on activities during the third year of the five-year US Government GHSA commitment, highlights how improved capacities have contributed to demonstrated impact in rapidly detecting and stopping outbreaks at their source. (CDC, 3/16/18)

See also:
PRESS RELEASE
CDC Warns of Deadly Outbreak of Yellow Fever in Brazil. CDC recommends that people who are unable to get yellow fever vaccine or aren't recommended to get it should avoid traveling to areas of Brazil where yellow fever vaccination is recommended. Travelers going to areas with ongoing outbreaks may consider getting a booster dose of yellow fever vaccine if it has been 10 or more years since they were vaccinated. (CDC, 3/16/18)
REPORT
Vaccine-Derived Poliovirus Outbreaks and Events - Three Provinces, Democratic Republic of the Congo, 2017. Longstanding circumstances within Haut Lomami, Maniema, Tanganyika, and other eastern provinces, including insufficient human resources, insecurity, poor roads, lack of transport and cold chain equipment, riverine and other difficult-to-reach communities, and communities historically refusing vaccination have posed challenges to routine immunization, SIA implementation, and AFP surveillance and have resulted in susceptibility to the emergence of VDPV. (CDC, 3/16/18)
NEWS
AIDS Researcher Favored to Be Next CDC Chief. Robert Redfield, an HIV/AIDS expert at the University of Maryland Medical Center, is being vetted by the Trump administration to run the CDC. Redfield emerged this week as the favored choice to replace former CDC Director Brenda Fitzgerald, who resigned in late January after POLITICO reported she had traded tobacco, drug and food stocks while heading the public health agency.  (Politico, 3/16/18)
BLOG
A Somber Centennial - US Health Diplomacy Aims to Prevent Repeat of Catastrophic Flu Pandemics. This year seems on track as a particularly difficult flu season in the United States, with outbreaks across the country. The past reminds us that we have come far in the fight against the influenza virus, but vigilant we must remain. (Department of State, 3/15/18)
PRESS RELEASE
USDA Announces Regionalization Agreement with South Korea to Help Protect US Trade During HPAI Detections. The United States Department of Agriculture today announced an agreement with the government of South Korea that significantly reduces negative impacts on trade should another detection of highly pathogenic avian influenza (HPAI) occur in the United States. The agreement will allow for trade restrictions at the state level instead of the country level during any future HPAI detection.  (USDA, 3/15/18)
PRESS RELEASE
H7N9 Influenza Vaccine Clinical Trials Begin. The Phase 2 studies, sponsored by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, will test different dosages of the inactivated influenza vaccine candidate (called 2017 H7N9 IIV) as well as different vaccination schedules. (NIH, 3/15/18)
SOLICITATION
Business Intelligence for Influenza Vaccine Supply Chain Analytics. The Department of Health and Human Services Biomedical Advanced Research and Development Authority is conducting market research on all qualified vendors of business intelligence software for influenza vaccine supply chain analytics. (Global Biodefense, 3/15/18)
NEWS
"Right-to-Try" Bill Rejected by House in Major Blow to GOP Efforts.  The controversial "right-to-try" bill would offer a pathway for patients with a terminal disease to get around Food and Drug Administration rules to request an experimental treatment from a drug maker before the agency has approved it. (STAT News, 3/13/18)
PRESS RELEASE
NIH Scientists Describe Potential Antibody Approach for Treating Multidrug-Resistant Klebsiella pneumoniae. Researchers are developing a promising alternative to antibiotic treatment for infections caused by Klebsiella pneumoniae bacteria resistant to carbapenem antibiotics. The approach uses antibodies to target the K. pneumoniae protective capsule polysaccharide, allowing immune system cells called neutrophils to attack and kill the bacteria.  (NIAID, 3/13/18)
WEBINAR
The US and Global Health Security at a Time of Transition. On Monday, March 12 the Kaiser Family Foundation held an event to explore these and other questions on the future of US global health security efforts with a panel of leading experts. Jen Kates, Vice President and Director of Global Health and HIV Policy, provided opening remarks, and Anne Schuchat, Acting Director, Centers for Disease Control and Prevention, gave a keynote address on US global health security efforts.  (Kaiser Family Foundation, 3/12/18)
BLOG
Shouting in the Dark: Emergency Communication in USVI After Irma and Maria. USVI Department of Health staff had to be creative and resourceful after the storms because the typical means of communication were down. The best ways to share information immediately after the storms was through paper flyers, radio, and in-person outreach. CDC and the US Postal Service assisted with printing and distributing a flyer on key health tips to every mailbox on all four islands. (CDC, 3/12/18)

See also: 
NEWS
USAID and FAO Working Together to Preempt the Next Global Pandemic. "Over the course of this relationship we've learned that there are many mutually beneficial areas of interest between the food and agricultural community and the human health community," said Dennis Carroll, Director of USAID's Global Health Security and Development Unit. (FAO, 3/9/18)
BROAD AGENCY ANNOUNCEMENT
Broad Agency Announcement. Medical countermeasure-related research submissions are encouraged under area 7: Facilitate Development of Medical Countermeasures to Protect Against Threats to US and Global Health Security. Proposers are encouraged to submit white papers by March 30, 2018 for current fiscal year awards. (FedBizOpps, 3/18)
ANNOUNCEMENT
Public Health Emergency Preparedness. CDC has launched a website to help the public health preparedness community raise awareness about the preparedness accomplishments of the PHEP program and its dedicated champions over the past 15 years.  (PHEP Impacts, 3/18)
WEBINAR
Regulatory Considerations for Strategic National Stockpile Products. CDC's Division of Strategic National Stockpile will host a webinar for public health partners from 1:30 to 2:30 p.m., ET, on Wednesday, March 21, to discuss threat-specific medical countermeasures and their anticipated regulatory mechanisms for the use of SNS medicines and supplies. The webinar is open to all federal, state, local, tribal, and territorial public health and emergency response partners. (NACCHO, 3/18)
Homeland Security & Disaster Preparedness
BLOG
Summary: The Department of Homeland Security Authorization Act of 2017. The legislation to authorize DHS has taken three years to hammer out, with considerable difficulty. Much of that difficulty stemmed from the plethora of congressional committees which oversee DHS, a problem which was somewhat resolved in the House early last year through a Memorandum of Understanding between its oversight committees. (Lawfare, 3/19/18)
NEWS
US Accuses Russia of Cyberattacks on Power Grid. The Trump administration announced extensive sanctions against Russia on Thursday morning, which included sanctions on the Internet Research Agency, a Russian troll farm that produced divisive political posts on American social media platforms during the 2016 presidential election. (CNN, 3/16/18)

PRESS RELEASE
DHS Working To Enhance School Safety, Increase Preparedness. In the wake of the recent attack in Parkland, Florida, the Department of Homeland Security is stepping up actions to better protect our nation's schools against gun violence, as well as other potential threats.  (Department of Homeland Security, 3/12/18)
NEWS
Mattis: It Would be "Very Unwise" for Syria to Use Weaponized Gas. Defense Secretary James Mattis reportedly warned the Syrian government on Sunday not to use chemical weapons following reports of chlorine attacks in Ghouta, an area surrounding the capital city of Damascus. (The Hill, 3/11/18)
REPORT
2018-2022 Strategic Plan: Federal Emergency Management Agency. This plan seeks to unify and further professionalize emergency management across the Nation and FEMA invites the whole community to join in embracing these priorities. (FEMA, 3/18)
Radiological & Nuclear Disaster Preparedness
GUIDANCE
A Decision Makers Guide: Medical Planning and Response for a Nuclear Detonation. This Manual will assist preparedness efforts and decision making by providing readily accessible information that quickly describes critical scientific and medical aspects of a nuclear incident as well as the response organization and resources anticipated to be required or available during a response. (Department of Health & Human Services, 3/15/18)
BLOG
NNSA Partnerships Advance Global Radiological Security. Radioactive sources can be incredibly dangerous in the hands of terrorist seeking to deploy a radiological dispersal device or "dirty bomb." The good news is that there are alternative technologies available that do not rely on radioactive sources. NNSA plays a major role in encouraging transition to these technologies.  (NNSA, 3/13/18)
BLOG
Lessons from Fukushima: New Guide Provides Answers to Save Lives and Improve Emergency Medical Response. During the response to the Fukushima Daiichi nuclear power plant disaster in Japan over seven years ago, integration of large amounts of complex information and evidence-based guidance into real-time decision making and response was shown to be nearly impossible without direct contact between leaders and subject matter experts. (ASPR, 3/12/18)
Science & Technology Policy
BLOG
Leap of Faith or Smart Investment? Early Integration of Whole Genome Sequencing in Healthcare Systems. Discovery science in genomic medicine has generally enjoyed longstanding large collaborations for data sharing and joint analyses. Synergies among collaborators has accelerated major advances in our understanding of the genetic basis of health and diseases.  (CDC, 3/16/18)
NEWS
NIAID Commits $12M to Form New Genomic Centers for Infectious Diseases. With the new grant, the NIAID is aiming to fund two to three new GCIDs to create large-scale genomic resources, including sequencing and experimental data, that will be made publicly accessible to the infectious disease research community. (GenomeWeb, 3/16/18)
FUNDING OPPORTUNITY
Genomic Centers for Infectious Diseases. The purpose of this initiative is to support Genomic Centers for Infectious Diseases (GCID) to promote broad use and expand the application of genomics technologies and computational analysis to understand infectious diseases, with an emphasis on pathogens, their interaction with the host and microbiome, and to aid in the development of novel genomics-based tools to diagnose, prevent and treat infectious diseases. (Grants.gov, 3/15/18)
NEWS
SEC Charges Theranos and CEO Elizabeth Holmes with Fraud. The Securities and Exchange Commission on Wednesday charged Theranos and CEO Elizabeth Holmes with fraud, capping off a remarkable downfall for a once high-flying company that promised to revolutionize the blood testing industry but instead became a parable for Silicon Valley hype and hubris. (STAT News, 3/14/18)
WORKSHOP
Promoting the Use of Complex Innovative Designs in Clinical Trials. On March 20th, FDA is conducting a public workshop to discuss the use of complex innovative designs (CID) in clinical trials of drugs and biological products to inform regulatory decision making. This meeting will inform development of a guidance document as required by the 21st Century Cures Act (Cures Act) and is being conducted to meet the performance goal of convening a public workshop on CID included in the sixth authorization of the Prescription Drug User Fee Act. (FDA, 3/14/18)
This Week's Hearings
Impacts of the 2017 Wildfires in the United States. US House Committee on Transportation & Infrastructure, Subcommittee on Economic Development, Public Buildings, and Emergency Management. 3/20/18, 10:30 AM. Rayburn 2167. More
Bureaucratic Challenges to Hurricane Recovery in Puerto Rico. US House Committee on Oversight & Government Reform, Subcommittee on National Security. 3/21/18, 2 PM. Rayburn 2154. More
Reviewing Department of Defense Strategy, Policy, and Programs for Countering Weapons of Mass Destruction for Fiscal Year 2019. US House Committee on Armed Services, Subcommittee on Emerging Threats and Capabilities. 3/22/18, 10:30 AM. Rayburn 2212. More
 

 

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