New York News in Research: May  2017
Highlights
Weill Cornell Medicine Team Creates Self-Renewing Hematopoietic Stem Cells for Transplantation


Researchers at Weill Cornell Medicine have discovered an innovative method to make an unlimited supply of healthy blood cells from the readily available cells that line blood vessels. This achievement marks the first time that any research group has generated such blood-forming stem cells. The research was partially funded by the New York State Stem Cell Science program, known as NYSTEM.   Take a closer look.

Cancer
NYU Langone Research Leads to Accelerated Approval of Bladder Cancer Immunotherapy Drug

Findings from a clinical trial led by a researcher at NYU Langone's Perlmutter Cancer Center helped pave the way for the recent, accelerated approval by the United States Food and Drug Administration (FDA) of a highly effective immunotherapy as a first-line treatment for patients with advanced bladder cancer who are not eligible for treatment with standard chemotherapy.  Take a closer look.
  
Albert Einstein College of Medicine Research Leads to New Drug for Hard-to-Treat Lymphomas

Japan has become the first country to approve a lymphoma drug developed through research at Albert Einstein College of Medicine. This also marks the first time that an Einstein-licensed drug has been approved for patient use.  Take a closer look.
  
Cardiology
University of Rochester Medical Center Researchers Lead First Worldwide Trial to Test Defibrillators in Diabetes Patients

Individuals with diabetes have a high incidence of heart problems, including sudden cardiac death. A study led by researchers at URMC will determine if a subcutaneous implantable cardiac defibrillator (S-ICD) increases survival in this growing group of patients Take a closer look.
  
NYIT College of Osteopathic Medicine Researchers Find Simpler Way to Link Atherosclerosis to Heart Disease

New research from NYIT has found that by examining the health of peripheral arteries, providers could better predict the risk of patients developing ischemic cardiovascular disease Take a closer look.
  
Columbia University Medical Center: Smoking-Related Heart Disease Tied to Effects of a Single Gene

Researchers have found a genetic explanation for how smoking can lead to coronary heart disease (CHD). Many people have a protective gene type that reduces levels of an enzyme connected to artery-clogging fatty plaques and CHD. However, in people carrying this gene, smoking counteracts the protective effect Take a closer look.
  
Neurology
University of Rochester Medical Center: Retraining the Brain to See After Stroke

Patients who went partially blind after suffering a stroke regained large swaths of rudimentary sight after undergoing visual training designed by researchers at the University of Rochester Medical Center's Flaum Eye Institute.  Take a closer look.
  
Icahn School of Medicine at Mount Sinai Study Reveals How Learning in the Present Shapes Future Learning

Neurons in the prefrontal cortex "teach" neurons in the hippocampus to "learn" rules that distinguish memory-based predictions in otherwise identical situations, suggesting that learning in the present helps guide learning in the future, according to research published in the journal Neuron Take a closer look.
  
Columbia University Medical Center: Schizophrenia Signs in Mice Linked to Uncoordinated Firing of Brain Cells, Says Study

Researchers at Columbia University have discovered that a small group of neurons fired haphazardly in mice with signs of schizophrenia. The findings suggest that a breakdown in the synchronized behavior of these brain cells could produce the classic disordered thinking and perceptions associated with the disease.   Take a closer look.
  
University at Buffalo Jacobs School of Medicine and Biomedical Sciences: Study of Those Who Survive With HIV, Without Medicine, Could Yield Medicine for Those Who Do Not

A small percentage of the world's population ­- about 1 percent - can be infected with the HIV virus but not progress to AIDS, and researchers do not know why.   Take a closer look.
  
Weill Cornell Medicine: New Study Finds Endoscopic Sleeve Gastroplasty an Effective Treatment for Some Obese Patients

A new weight loss procedure that reduces the size of the stomach without the need for surgery known as endoscopic sleeve gastroplasty (ESG) is safe and effective way for the treatment obesity and obesity-related comorbidities such as diabetes, high blood pressure and fatty liver, according to a new study by NewYork-Presbyterian and Weill Cornell Medicine researchers.   Take a closer look.
  
SUNY Upstate Medical University Researchers Say Biomarker Found in Saliva Can Identify Concussion, Predict Length of Recovery

Researchers at SUNY Upstate Medical University and Penn State University have identified a novel and accurate biomarker that both identifies concussion in children, and predicts the length of recovery.   Take a closer look.
  
Stony Brook Medicine: U.S. Veterans With Heart Disease and Depression Face Difficulties Affording Healthcare

A study of more than 13,000 veterans with heart disease revealed that for those who also had depression, gaining access to and affording healthcare and medications is more difficult than those without depression. Take a closer look.
  
SUNY Downstate Medical Center: Pilot Eye Movements Change Noticeably By Two Hours In-Flight

Pilot fatigue is a major contributor to aviation disasters, but coming up with an objective measure of fatigue has long eluded supervisors in both military and commercial airlines. Standard practice involves a combination of subjective self-report measures by the pilot, and an assessment by commanding officers.   Take a closer look.
  
University of Buffalo Jacobs School of Medicine and Biomedical Sciences: IBS Patients (Can't Get No) Satisfaction

Patient satisfaction is playing an increasingly important role in evaluating the quality of health care and reimbursing physicians for it. Exactly what drives that satisfaction has been difficult to determine.   Take a closer look.
  
Albert Einstein College of Medicine Shares in $2.9 Million Grant to Combat Breast Cancer Metastasis

Researchers at Albert Einstein College of Medicine and three other institutions are sharing a five-year, $2.9 million grant from the National Cancer Institute (NCI) to study how different types of cells influence breast cancer metastasis-the process by which cancer cells spread from the primary tumor to other parts of the body and that causes 90 percent of breast cancer-related deaths.   Take a closer look.
  
New York Medical College: Ashok Kumar, Ph.D., Receives Two Grants from National Institutes of Health 

Ashok Kumar, Ph.D., professor of pathology, New York Medical College, received two grants in the amounts of $615,000 and $370,001 from National Institutes of Health for "Non-coding Variants of Angiotensinogen Gene and Hypertension." The study will evaluate the impact of western diet on molecular mechanisms involved in hypertension and other cardiovascular disease with special emphasis on the  role of renin-angiotensin system. 
  
Icahn School of Medicine at Mount Sinai Researchers Receive Major NIH Award for Autism Genetics Research

Researchers from the Icahn School of Medicine at Mount Sinai, The Broad Institute of MIT and Harvard, University of Pittsburgh School of Medicine, University of California-San Francisco, and Carnegie Mellon University have been awarded $7million from the National Institute of Mental Health to extend the work of the Autism Sequencing Consortium (ASC), an international research consortium established by these institutions in 2010 to collect and share samples and genetic data from individuals diagnosed with autism spectrum disorder (ASD).   Take a closer look.
  
Hofstra Northwell School of Medicine: Renowned Cardiologist Cindy Grines, MD, Joins Hofstra Northwell

Northwell Health announced that Cindy Grines, MD, one of the nation's preeminent cardiologists, has joined Northwell Health and was appointed chair of cardiology at the Hofstra Northwell School of Medicine.   Take a closer look.
  
Weill Cornell Medicine: WorldQuant Initiative for Quantitative Prediction Established

Weill Cornell Medicine today announced a gift made by WorldQuant, LLC ("WorldQuant")  and Igor Tulchinsky that will further realize the promise of precision medicine. The $5 million gift establishes a new initiative that will use predictive tools to enhance Weill Cornell Medicine's capability to diagnose and treat a variety of illnesses, with the goal of improving outcomes for patients.   Take a closer look.
  
Stony Brook Medicine: Two Physicians Recognized for Novel Work in Cancer, Antifungal Research Named to AAP

Stony Brook University School of Medicine physician-scientists Ute Moll, MD, and Maurizio Del Poeta, MD, have been elected into the prestigious Association of American Physicians (APP). The AAP recognizes individuals who have demonstrated outstanding professional achievement in the pursuit of medical knowledge and the advancement of clinical science through experimentation and discovery.   Take a closer look.
  
New York Medical College: The 21st Annual Medical Student Research Forum Boasts Broad Range of Student Scientific Investigations

The 21st Annual Medical Student Research Forum held on March 6 featured a record-breaking number of student submissions. Despite being rescheduled due to a snowstorm, more than 50 poster presentations overflowed from the Medical Education Center lobby and lined the hallway of the Basic Sciences Building, followed by five oral presentations.   Take a closer look.
  

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