The best way to combat isolation and loneliness is to make time in your caregiving routine to focus on taking care of yourself with some sort of social interaction to build relationships.  Social relationships benefit health with their supportive nature by encouraging health-promoting behaviors and discouraging health-damaging behaviors.  It is important to maintain your sense of self and participate in activities that make you feel renewed.  Respite care can allow a caregiver to focus on their own personal needs without worrying about the safety of their care recipient.  Support groups or online support forums with common ground for caregivers in similar situations is another good way to interact.  When you are lonely, you lose impulse control and become less concerned with interactions and more concerned with self-preservation.  Involvement in your own interests may help you feel connected to your sense of self and help keep you in touch with your friends and loved ones.