From Dr. Josh Siegle, who worked with New Scale to develop the MPM System:
"The Allen Institute for Brain Science has performed an extensive characterization of the response properties of cells in individual visual areas using 2-photon imaging of genetically encoded calcium sensors. But to understand how the visual system achieves dynamic coordination between brain regions, it is necessary to monitor the activity of multiple areas simultaneously with single-spike temporal resolution.
To study this, we built a rig capable of targeting arrays of extracellular electrodes to retinotopically matched regions of mouse cortical visual areas, including AM, PM, RL, LM, and V1. Using miniature 3-axis linear stages from New Scale Technologies, we are able to align up to six 384-channel Neuropixels probes to area maps... "
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