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Spotlight on: Dr. Jeffrey Gerber
Dr. Gerber Receives Clinically Innovative Research Award

Jeffrey Gerber, MD, PhD, MSCE, CPCE Associate Director for Inpatient Research Activities, and colleagues will receive the Pediatric Infectious Disease Society (PIDS) Education and Research Foundation’s 2016 Caroline B. Hall Clinically Innovative Research Award for their article, “Variation in Antibiotic Prescribing Across a Pediatric Primary Care Network” published in the Journal of the Pediatric Infectious Diseases Society in December 2015.

The Caroline B. Hall Clinically Innovative Research Award was established to celebrate the contributions of Dr. Hall to the field of pediatric infectious diseases and will be presented annually to a first-authored faculty member of a paper that best illustrates Dr. Hall’s innovation through clinical teaching and research.  Click here to learn more about the award.
Upcoming Events

Pediatric Grand Rounds
Date: Wednesday, September 7, 2016
Time: 8-9 am
Location: Stokes Auditorium
David Rubin, MD, MSCE will present a lecture titled "The Changing Health Care Landscape: Ensuring Coverage and Access to Services for Children". Upon completion of this live activity, participants will be able to: 1. Discuss the risks to low- and moderate-income families in the insurance market. 2. Explain the importance of the Affordable Care Act, Medicaid and CHIP for children and families. 3. Identify ways to protect families and strengthen coverage and access to care for children

Physician Headshot Photo Shoot
Date: Tuesday September 20, 2016
Location: Stokes Auditorium
Attending physicians can get a free headshots every two years. Fellows, residents and other clinical staff can participate for $75, which may be paid through their cost center. To schedule your 15 minute appointment, or to ask questions, contact Denise Ambron .

Philadelphia Research Community Conference
Date: Wednesday September 21, 2016
Time: 2-6 pm
Location: To be determined 
The conference is an opportunity to engage and network with the research community around the topic of engaging with the public. It is a free event that is hosted by the Recruitment Enhancement Core in partnership with the Prosper Planning committee and PENN.

CHOP’s Global Health Conference
Dates: September 30 - October 1, 2016
The 2016 CHOP Global Health Conference will explore the ingredients of successful pediatric global health partnerships through a diverse range of perspectives. Participants will be challenged to collaborate to build stronger networks in pediatric global health. Register online by September 16, 2016.

3rd Annual Penn/CHOP Microbiome Symposium 
Date: Thursday October 27, 2016
Time: 8 am - 7 pm
Location: Biomedical Research Building II/III Auditorium
Speakers Include: Jillian Banfield, Sarah Cherry, Michael Fischbach, Ivaylo Ivanov,  Christopher Mason, Susan Lynch, Forest Rohwer, Boris Striepen. Symposium registrants may submit 40” x 60” posters. Four abstracts will be chosen for presentation during the symposium as well as a $250 cash prize. Poster abstracts (500 words max.) must be submitted to April Weakley by October 7, 2016. Register for the symposium by October 14, 2016.

CPCE in
the News!
Recent Publications
This methods paper by Marcl Drees, Jeffrey Gerber, Daniel Morgan, and Grace Lee presents key considerations for using administrative and surveillance data in healthcare epidemiology and antimicrobial stewardship (HE&AS), including types of data available and potential use, data limitations, and the importance of validation. 

Supportive care utilization and treatment toxicity in children with Down syndrome and acute lymphoid leukaemia at free-standing paediatric hospitals in the United States
Although inferior outcomes of children with Down syndrome (DS) and acute lymphoid leukaemia (ALL) are established, national supportive care patterns for these patients are unknown. A validated retrospective cohort of paediatric patients diagnosed with ALL from 1999 to 2011 was assembled from the US Pediatric Health Information System (PHIS) database to examine organ toxicity, sepsis, and resource utilization in children with and without DS. 

Safety of Automatic End Dates for Antimicrobial Orders to Facilitate Stewardship
Following implementation of automatic end dates for antimicrobial orders to facilitate antimicrobial stewardship at a large, academic children's hospital, no differences were observed in patient mortality, length of stay, or readmission rates, even among patients with documented bacteremia. 

Diagnosis of Invasive Fungal Disease in Pediatric Cancer and Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis 
CPCE researchers systematically reviewed and analyzed the available data for galactomannan (GM), beta-D-glucan (BG), and polymerase-chain reaction (PCR)-based assays to detect invasive fungal disease (IFD) in pediatric cancer or hematopoietic stem cell transplantation (HSCT) patients when used as screening tools during immunosuppression or as diagnostic tests in patients presenting with symptoms such as fever during neutropenia (FN). 

See more...

Funding Opportunities

CHOP Cares Community Grants (due September 15th)
The CHOP Cares Community Grants is an innovative initiative in which employees can apply for grants of up to $5,000 to fund projects that fill an identified health care need benefiting children and families in Pennsylvania and New Jersey. CHOP Cares Grants provide employees with the resources they need to become active leaders in their community, advancing children's health by aligning their interests with data derived from the hospital's community health needs assessment. The program is funded by individual donations, Hospital contributions and money raised through the Pennsylvania CHOP Specialty License Plate Program.

CPCE Pilot Grant Program (due Oct 1)
CPCE offers Pilot Grants twice per year to support CHOP investigators in clinical effectiveness studies that will attract external support for larger-scale projects. Investigators from all CHOP departments and divisions, including fellows in their final year of fellowship transitioning to a faculty position at CHOP, are encouraged to apply. Selected proposals will be supported for up to a maximum of $10,000 for one year. Proposals are typically due April 1 and October 1.

Burroughs Wellcome Fund: Career Awards for Medical Scientists (due Oct 3)
The Career Awards for Medical Scientists (CAMS) is a highly competitive program that provides $700,000 awards over five years for physician-scientists, who are committed to an academic career, to bridge advanced postdoctoral/fellowship training and the early years of faculty service. Proposals must be in the area of basic biomedical, disease-oriented, or translational research. Candidates must have received their most recent earned clinical doctorate degree within the last 11 calendar years; Candidates holding K awards are eligible.

Center for Perinatal and Pediatric Health Disparities Research (CPHD) Pilot Grants (due Oct 5)
CPHD offers a Pilot Project Funding Opportunity once a year through its Pilot Grant Program. The purpose of this program is to promote and support health disparities (HD) investigators in research specific to perinatal and pediatric health disparities and health equity. The CPHD Pilot Grant Program aims to engage fellows and junior faculty in HD research and to assist established faculty in developing new lines of research in this area. Investigators from all institutions and disciplines including fellows are encouraged to apply; however, at least one investigator and/or consultant on the project must be from CHOP. The award range is between $2,500 and $10,000 for one year. Projects must be completed within one year. Applications are due October 5. Successful applicants will be notified in November. Awards will have a start date on or around December 1.

American Cancer Society: The Role of Health Policy and Health Insurance in Improving Access to and Performance of Cancer Prevention, Early Detection, and Treatment Services (due Oct 15)
Supports research that evaluates the impact of the many changes now occurring in the healthcare system with a particular focus on cancer prevention, control, and treatment. New health public policy initiatives such as the new federal and state marketplaces that have expanded insurance coverage, as well as Medicaid expansion in some states, create natural experiments ripe for evaluation. Research to be funded by this RFA should focus on the changes in national, state, and/or local policy and the response to these changes by healthcare systems, insurers, payers, communities, practices, and patients.

OnPAR Program for Unfunded NIH Proposals
Last year, the NIH received approximately $30 billion in federal support. In spite of this amount, about 42,500 grants were not funded. To address these unfunded proposals, the NIH has a new Pilot Program that is designed to match researchers with nonprofit disease Foundations or with investments from private companies. Through a new collaboration between the NIH and the private contractor Leidos, researchers can now upload their unfunded NIH Proposals into an online portal at the Online Partnership to Accelerate Research (OnPAR). Foundations and other potential funders can review the NIH scores, and decide whether they might be interested in funding the Projects. Currently, this Pilot Program allows researchers with priority scores better than the 30th percentile to submit their abstracts. Interested Foundations might ask that a researcher send their full NIH Application along with its scores. The consensus opinion is that there are a lot of worthy grants being submitted to the NIH, but there is only so much funding available. OnPAR is one way of trying to match researchers with private Foundations. 

About CPCE
We are a pediatric research center dedicated to discovering and sharing knowledge about best practices in pediatric care by facilitating, organizing and centralizing the performance of clinical effectiveness research -- research aimed at understanding the best ways to prevent, diagnose and treat diseases in children. CPCE’s multidisciplinary team conducts research on a diverse range of clinical effectiveness topics grouped within four areas of research: