Dear Colleagues,
The Multipurpose Prevention Technologies (MPTs) field is steadily evolving and expanding. Provided below are links to recent publications, media articles, and other resources relevant to MPTs to keep you up-to-date. Please note that contents are neither endorsed by nor necessarily represent the views of the Initiative for Multipurpose Prevention Technologies (IMPT), and that due to publication copyright and permissions restrictions, full-text versions of resources may not be publicly available. If you have a resource to include in our next issue, please send to Vanetta Thomas at vthomas@cami-health.org. Previous issues are available on the IMPT website.
Best,
IMPT Secretariat Staff
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Journal Articles
A First-in-Human Trial of MIV-150 and Zinc Acetate Co-Formulated in a Carrageenan Gel: Safety, Pharmacokinetics, Acceptability, Adherence and Pharmacodynamics
. Friedland, B,A., Hoesley, C.J., Plagianos, M., Hoskin, E., Zhang, S., Teleshova, N., ...Creasy, G. (2016, July). Journal of Acquired Immune Deficiency Syndromes.
A Novel Microbicide/Contraceptive Intravaginal Ring Protects Macaque Genital Mucosa against SHIV-RT Infection Ex Vivo. Villegas, G., Calenda, G., Ugaonkar, S., Zhang, S., Kizima, L, Mizenina, O., ... Zydowsky, T.M. (2016, July). PLOS One.
Abolishing HIV-1 infectivity using a polypurine tract-specific G-quadruplex forming oligonucleotide. Voges, M., Schneider, C., Sinn, M., Hartig, J.S., Reimer, R., Hauber, J., & Moelling, K. (2016, July). BMC Infectious Diseases.
Characteristics of women screened for a contraceptive intravaginal ring study in Kisumu, Kenya, 2014. McLellan-Lemal, E., Gust, D.A., Gvetadze, R., Furtado, M., Otieno, F.O., Desai, M., ...Makanga, E.M. (2016, July). Research Journal of Women's Health.
In vitro exposure to PC-1005 and cervicovaginal lavages from women vaginally administered PC-1005 inhibit HIV-1 and HSV-2 infection in human cervical mucosa. Villegas, G., Calenda, G., Zhang, S., Mizenina, O., Kleinbeck, K., Cooney, M.L., ... Teleshova, N. (2016, July). Antimicrobial Agents and Chemotherapy.
Matrix and reservoir-type multipurpose vaginal rings for controlled release of dapivirine and levonorgestrel. Boyd, P., Fetherston, S.M., McCoy, C.F., Major, I., Murphy, D.J., Kumar, S., Holt, J., ... Malcolm, R.K. (2016, September). International Journal of Pharmaceutics, 511(1), 619-629.
Microbicide vaginal rings: Technological challenges and clinical development
. Malcolm, R.K., Boyd, P.J., McCoy, C.F., Murphy, D.J. (2016, August). Advanced Drug Delivery Reviews, volume 103, 33-56.
Planning for HIV preexposure prophylaxis introduction: lessons learned from contraception. Delany-Moretlwe, S., Mullick, S., Eakle, R., Rees, H. (2016, January). Current Opinion in HIV and AIDS, 11(1), 87-93.
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2016 Pipeline Report. HIV and TB. Drugs, Diagnostics, Vaccines, Preventive Technologies, Research Toward a Cure, and Immune-Based and Gene Therapies in Development. Clayden, P., Collins, S., Frick, M., Harrington, M., Horn, T., Jefferys, R., Lessem, E., & McKenna, L. (2016, July 15).
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