Most patients will have only one transplant during their lifetime. We all hope that this one transplant is all that the person will need, and that it will work very well for as long as possible. In fact, many patients live long, normal lives after their transplant and will never need another one. However, the transplant sometimes fails and the patient then needs to go back on dialysis. The question then arises: can one have another transplant? Having a second, or even a third or fourth kidney transplant is actually not that uncommon. Even if the first transplant did not work very well, a subsequent transplant might in fact work extremely well. However, there are some things to be aware of, when thinking about getting another transplant.